Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Allyn M. Lambertz"'
Autor:
Katherine N. Gibson-Corley, Alexander W. Boyden, Mariah R. Leidinger, Allyn M. Lambertz, Georgina Ofori-Amanfo, Paul W. Naumann, J. Adam Goeken, Nitin J. Karandikar
Publikováno v:
PeerJ, Vol 4, p e1600 (2016)
Experimental autoimmune encephalomyelitis (EAE) is a well-established mouse model for multiple sclerosis and is characterized by infiltration of mononuclear cells and demyelination within the central nervous system along with the clinical symptoms of
Externí odkaz:
https://doaj.org/article/5a0113dc28dc4e178e8a0709e9a78f2e
Autor:
Chandni Desai, Jon Thomason, Qining Qian, Sarah L. Hall, Benjamin W. Darbro, Colleen Fullenkamp, Munir R. Tanas, Adam J. Dupuy, Nicole Merritt, Allyn M. Lambertz
Publikováno v:
Oncotarget
TAZ and YAP are transcriptional coactivators negatively regulated by the Hippo pathway that have emerged as key oncoproteins in several cancers including sarcomas. We hypothesized that loss of expression of the Hippo kinases might be a mechanism of a
Autor:
Allyn M. Lambertz, Katherine N. Gibson-Corley, Jeremy A. Sandgren, Benjamin J. Weidemann, Nicole A Pearson, Nicole K. Littlejohn, Colin M.L. Burnett, Kristin E. Claflin, Donald A. Morgan, Kamal Rahmouni, Justin L. Grobe
Publikováno v:
Journal of Clinical Investigation. 127:1414-1424
Leptin contributes to the control of resting metabolic rate (RMR) and blood pressure (BP) through its actions in the arcuate nucleus (ARC). The renin-angiotensin system (RAS) and angiotensin AT1 receptors within the brain are also involved in the con
Autor:
Chen Zhao, Mariah R. Leidinger, Katherine N. Gibson-Corley, Allyn M. Lambertz, Yan Xiu, Wingel Y. Xue
Publikováno v:
Stem Cells. 35:777-786
Previously we have shown that loss of non-canonical NF-κB signaling impairs self-renewal of hematopoietic stem/progenitor cells (HSPCs). This prompted us to investigate whether persistent activation of the non-canonical NF-κB signaling will have su
Autor:
Benjamin J. Miller, Georgina K. Ofori-Amanfo, Mohammed M. Milhem, Johanna Savage, Colleen Fullenkamp, Erica C. Savage, Munir R. Tanas, Christopher S. Stipp, Stephanie D. Ivins, Omar I. Jaber, Brittany L. Pakalniskis, Sarah L. Hall, Allyn M. Lambertz
Publikováno v:
Oncotarget
TAZ (WWTR1) and YAP are transcriptional coactivators and oncoproteins inhibited by the Hippo pathway. Herein we evaluate 159 sarcomas representing the most prevalent sarcoma types by immunohistochemistry for expression and activation (nuclear localiz
Publikováno v:
The American Journal of Pathology
Dipeptidyl peptidase 4 (DPP4, CD26), a type II transmembrane ectopeptidase, is the receptor for the Middle Eastern respiratory syndrome coronavirus (MERS-CoV). MERS emerged in 2012 and has a high mortality associated with severe lung disease. A lack
Autor:
J. Adam Goeken, Allyn M. Lambertz, Paul W. Naumann, Nitin J. Karandikar, Mariah R. Leidinger, Katherine N. Gibson-Corley, Georgina K. Ofori-Amanfo, Alexander W. Boyden
Publikováno v:
PeerJ
PeerJ, Vol 4, p e1600 (2016)
PeerJ, Vol 4, p e1600 (2016)
Experimental autoimmune encephalomyelitis (EAE) is a well-established mouse model for multiple sclerosis and is characterized by infiltration of mononuclear cells and demyelination within the central nervous system along with the clinical symptoms of
Autor:
Allyn M. Lambertz, Paul B. McCray, Michael J. Welsh, Leah R. Reznikov, Phil Karp, David A. Stoltz, Georgina K. Ofori-Amanfo, David K. Meyerholz
Genetically engineered pigs are increasingly recognized as valuable models for the study of human disease. Immunohistochemical study of cellular markers of disease is an important tool for the investigation of these novel models so as to evaluate gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68aa4957c8025f83dd78b8ab6058ead2
https://europepmc.org/articles/PMC4805467/
https://europepmc.org/articles/PMC4805467/
Publikováno v:
The American journal of pathology. 186(1)
Dipeptidyl peptidase 4 (DPP4, CD26), a type II transmembrane ectopeptidase, is the receptor for the Middle Eastern respiratory syndrome coronavirus (MERS-CoV). MERS emerged in 2012 and has a high mortality associated with severe lung disease. A lack
Autor:
Katherine A. White, David A. Pearce, Xiao-Jun Wang, Constantin Trantzas, Jason T. Struzynski, Christopher S. Rogers, Bryan T. Davis, Allyn M. Lambertz, Richard Van Rheeden, Brian A. Dacken, David K. Meyerholz, Krystal L. Weber, Benjamin W. Darbro, Frank Rohret, Judy A. Rohret, Chun-Hung Chan, Attila D. Kovács, Michael C. Kruer, Rosanna Beraldi, Jill M. Weimer
Publikováno v:
Human molecular genetics. 24(22)
Ataxia telangiectasia (AT) is a progressive multisystem disorder caused by mutations in the AT-mutated (ATM) gene. AT is a neurodegenerative disease primarily characterized by cerebellar degeneration in children leading to motor impairment. The disea