Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Allyn Franklin"'
Autor:
Dianne P. Figlewicz, Elaine R. Peskind, Kim M. Hansen, William A. Banks, Patricia Szot, Allyn Franklin, Kristin M. Bullock, Timothy Petru Beuca, Murray A. Raskind
Publikováno v:
Neuroscience. 355:9-21
Neuroinflammation is proposed to be an important component in the development of several central nervous system (CNS) disorders including depression, Alzheimer's disease, Parkinson's disease, and traumatic brain injury. However, exactly how neuroinfl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8612f10e69594401c8bd50fb7e8718
https://doi.org/10.1016/j.neuroscience.2017.04.028
https://doi.org/10.1016/j.neuroscience.2017.04.028
Autor:
Sylvia S. White, Carl Sikkema, Allyn Franklin, Murray A. Raskind, C.W. Wilkinson, Patricia Szot, S. Foster, L. Knight
Publikováno v:
Neuroscience. 216:143-157
The locus coeruleus (LC) is the major loci of noradrenergic innervation to the forebrain. Due to the extensive central nervous system innervation of the LC noradrenergic system, a reduction in the number of LC neurons could result in significant chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a5057f658bafe7e525de93a3babc03
https://doi.org/10.1016/j.neuroscience.2012.04.046
https://doi.org/10.1016/j.neuroscience.2012.04.046
Autor:
Sylvia S. White, Patricia Szot, J. Lynne Greenup, Murray A. Raskind, James B. Leverenz, Allyn Franklin, Pamela J. McMillan
Publikováno v:
Brain Research. 1373:240-252
In Parkinson's disease (PD), there is a significant loss of noradrenergic neurons in the locus coeruleus (LC) in addition to the loss of dopaminergic neurons in the substantia nigra (SN). The goal of this study was to determine if the surviving LC no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44154b9f5269b5fe896bb0f317960ee6
https://doi.org/10.1016/j.brainres.2010.12.015
https://doi.org/10.1016/j.brainres.2010.12.015
Autor:
Murray A. Raskind, Yangqing Wang, Charles W. Wilkinson, Igor Vidaurrazaga, Patricia Szot, Luisa Ugedo, Allyn Franklin, Cristina Miguelez, Carl Sikkema
Publikováno v:
Neuropharmacology. 101
Depression is a common co-morbid condition most often observed in subjects with mild cognitive impairment (MCI) and during the early stages of Alzheimer's disease (AD). Dysfunction of the central noradrenergic nervous system is an important component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453034801ca7908ca0c786b8247ec745
https://pubmed.ncbi.nlm.nih.gov/26362360
https://pubmed.ncbi.nlm.nih.gov/26362360
Autor:
Ken Mackie, Christian Wade, George Kunos, Nephi Stella, Anke Witting, Lisa Walter, Allyn Franklin, Yiheng Xie
Publikováno v:
ResearcherID
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
During neuroinflammation, activated microglial cells migrate toward dying neurons, where they exacerbate local cell damage. The signaling molecules that trigger microglial cell migration are poorly understood. In this paper, we show that pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409842eae98295b02702164f1392c887
https://doi.org/10.1523/jneurosci.23-04-01398.2003
https://doi.org/10.1523/jneurosci.23-04-01398.2003
Publikováno v:
Journal of Child Neurology. 16:849-853
Neurogenesis and neuronal differentiation are determined by the NeuroD homologues, transcription factors belonging to a family of basic helix-loop-helix proteins. The authors used in situ hybridization with full-length riboprobes for NeuroD1, NeuroD2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762183608c821634022d95905f0062fc
https://doi.org/10.1177/08830738010160111201
https://doi.org/10.1177/08830738010160111201
Publikováno v:
Etiology and Pathophysiology of Parkinson's Disease
1.1 Dopaminergic neuronal loss in Parkinson’s disease Parkinson’s disease (PD) is a neurological disorder that affects approximately 2% of the elderly population, and as our population continues to age, the incidence will only increase (Singh et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394ffb2e5772cc403e229a06f6fdf271
https://doi.org/10.5772/17094
https://doi.org/10.5772/17094
Autor:
Murray A. Raskind, Patricia Szot, Luisa Ugedo, Carl Sikkema, Cristina Miguelez, Allyn Franklin, Charles W. Wilkinson, Sylvia S. White
Degeneration of the noradrenergic neurons in the locus coeruleus (LC) is a major component of Alzheimer's (AD) and Parkinson's disease (PD), but the consequence of noradrenergic neuronal loss has different effects on the surviving neurons in the two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5697f80283bf85d51a7c35f95afe05f7
https://europepmc.org/articles/PMC4060967/
https://europepmc.org/articles/PMC4060967/
Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice
Autor:
Debby Van Dam, Allyn Franklin, Patricia Szot, Matthias Staufenbiel, Peter Paul De Deyn, Sylvia S. White
Publikováno v:
Neuroscience letters
Alzheimer's disease (AD), a neurodegenerative disorder, is characterized by the loss of neurons in specific regions of the CNS including the locus coeruleus (LC), the major noradrenergic locus in the CNS. Several animal models of AD have been develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e3f23adad93a41134cddca05a55a9e
https://pubmed.ncbi.nlm.nih.gov/19631722
https://pubmed.ncbi.nlm.nih.gov/19631722
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Focal cerebral ischemia (FCI) induces rapid neuronal death in the ischemic core, which gradually expands toward the penumbra, partly as the result of a neuroinflammatory response. It is known that propagation of neuroinflammation involves microglial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be585ab3b428ec91d08f32e04539cea3
https://pubmed.ncbi.nlm.nih.gov/12944505
https://pubmed.ncbi.nlm.nih.gov/12944505