Stereoselective synthesis of S-norvaline and related amino acids through a common intermediate.

Autor: Espinoza-Hicks JC; Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico., Chavez-Flores D; Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico., Zaragoza-Galan G; Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico., Camacho-Davila AA; Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico. acamach@uach.mx.

Publikováno v: Amino acids [Amino Acids] 2023 Jul; Vol. 55 (7), pp. 939-946. Date of Electronic Publication: 2023 Jun 09.

Substrate-Triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate.

Autor: McBride MJ; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Nair MA; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Sil D; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Slater JW; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Neugebauer ME; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, California 94720, United States., Chang MCY; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, California 94720, United States.; Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, and Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States., Boal AK; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Krebs C; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States., Bollinger JM Jr; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.

Publikováno v: Biochemistry [Biochemistry] 2022 Apr 19; Vol. 61 (8), pp. 689-702. Date of Electronic Publication: 2022 Apr 05.

Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.

Autor: Leclercq K; Neuroscience TA, UCB Biopharma, Braine-l'Alleud, Belgium., Afrikanova T; Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium., Langlois M; Luxembourg Center for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., De Prins A; Center for Neurosciences, C4N, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium., Buenafe OE; Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium., Rospo CC; Neuroscience TA, UCB Biopharma, Braine-l'Alleud, Belgium., Van Eeckhaut A; Luxembourg Center for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., de Witte PA; Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium., Crawford AD; Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium; Luxembourg Center for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Smolders I; Center for Neurosciences, C4N, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium., Esguerra CV; Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium; Chemical Neuroscience Group, Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway. Electronic address: c.v.esguerra@biotek.uio.no., Kaminski RM; Neuroscience TA, UCB Biopharma, Braine-l'Alleud, Belgium. Electronic address: rafal.kaminski@ucb.com.

Publikováno v: Epilepsy & behavior : E&B [Epilepsy Behav] 2015 Apr; Vol. 45, pp. 53-63. Date of Electronic Publication: 2015 Apr 03.

ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.

Autor: Tumurkhuu G; Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Koide N, Hiwasa T, Ookoshi M, Dagvadorj J, Abu Shadat Mohammod Noman, Iftakhar-E-Khuda I, Naiki Y, Komatsu T, Yoshida T, Yokochi T

Publikováno v: Innate immunity [Innate Immun] 2011 Feb; Vol. 17 (1), pp. 97-105. Date of Electronic Publication: 2009 Dec 18.

Zn-catalyzed asymmetric allylation for the synthesis of optically active allylglycine derivatives. Regio- and stereoselective formal alpha-addition of allylboronates to hydrazono esters.

Autor: Fujita M; Department of Chemistry, School of Science and Graduate School of Pharmaceutical Sciences, The University of Tokyo, The HFRE Division, ERATO, Japan Science Technology Agency, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Nagano T, Schneider U, Hamada T, Ogawa C, Kobayashi S

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2008 Mar 12; Vol. 130 (10), pp. 2914-5. Date of Electronic Publication: 2008 Feb 16.