Molecular modeling and synthesis of novel benzimidazole-derived thiazolidinone bearing chalcone derivatives: a promising approach to develop potential anti-diabetic agents.

Autor: Abbasi SA; Department of Chemistry, Hazara University, Mansehra, 21120, Pakistan., Rehman W; Department of Chemistry, Hazara University, Mansehra, 21120, Pakistan., Rahim F; Department of Chemistry, Hazara University, Mansehra, 21120, Pakistan., Hussain R; Department of Chemistry, Hazara University, Mansehra, 21120, Pakistan., Hawsawi MB; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, 21955, Saudi Arabia., Alluhaibi MS; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, 21955, Saudi Arabia., Alharbi M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia., Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, P.O. Box 19823 1441, Saudi Arabia., Khan S; Department of Chemistry, Abbottabad University of Science and Technology (AUST), Abbottabad, Pakistan., Rasheed L; Henan International Joint Laboratory of Nano-Photoelectric Magnetic Material, School of Material Science and Engineering, Henan University of Technology, Zhengzhou, 450001, Henan, China., Wadood A; Department of Biochemistry, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan., Ali Shah SA; Atta-Ur-Rahman Institute for Natural Product Discovery (AuRIns), Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam, Selangor, 42300, Malaysia.; Faculty of Pharmacy, Universiti Teknologi MARA Cawangan Selangor Kampus Puncak Alam, Bandar Puncak Alam, Selangor, 42300, Malaysia.

Publikováno v: Zeitschrift fur Naturforschung. C, Journal of biosciences [Z Naturforsch C J Biosci] 2024 Nov 20. Date of Electronic Publication: 2024 Nov 20.

Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.

Autor: Mughal EU; Department of Chemistry, University of Gujrat, Gujrat, 50700, Pakistan. Electronic address: ehsan.ullah@uog.edu.pk., Hawsawi MB; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, 21955, Saudi Arabia., Naeem N; Department of Chemistry, University of Gujrat, Gujrat, 50700, Pakistan., Hassan A; Department of Chemistry, University of Gujrat, Gujrat, 50700, Pakistan., Alluhaibi MS; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, 21955, Saudi Arabia., Ali Shah SW; Department of Pharmacy, University of Malakand, Chakdara, Dir, 18800, Khyber Pakhtunkhwa, Pakistan., Nazir Y; Department of Chemistry, University of Sialkot, 51300, Pakistan., Sadiq A; Department of Chemistry, Govt. College Women University, Sialkot, 51300, Pakistan., Alrafai HA; Department of Chemistry, Faculty of Science, King Khalid University, PO Box 9004, Abha, 61413, Saudi Arabia., Ahmed SA; Department of Chemistry, Faculty of Science, Umm Al-Qura University, Makkah, 21955, Saudi Arabia; Department of Chemistry, Faculty of Science, Assiut University, 71516, Assiut, Egypt. Electronic address: saahmed@uqu.edu.sa.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jul 05; Vol. 273, pp. 116523. Date of Electronic Publication: 2024 May 21.