Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alloysius Gomez"'
Autor:
Simon Houston, Alloysius Gomez, Andrew Geppert, Azad Eshghi, Derek S. Smith, Sean Waugh, Darryl B. Hardie, David R. Goodlett, Caroline E. Cameron
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum ssp. pallidum, is technically challenging due to high sample complexity, difficulties with obtaining sufficient quantities of bacteria for analysis, and the
Externí odkaz:
https://doaj.org/article/994e5ae992d940738c395daf9c2e6db8
Autor:
Sean Waugh, Akash Ranasinghe, Alloysius Gomez, Simon Houston, Karen V. Lithgow, Azad Eshghi, Jenna Fleetwood, Kate M. E. Conway, Lisa A. Reynolds, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionSyphilis is a chronic, multi-stage infection caused by the extracellular bacterium Treponema pallidum ssp. pallidum. Treponema pallidum widely disseminates through the vasculature, crosses endothelial, blood–brain and placental barriers
Externí odkaz:
https://doaj.org/article/aafce8b765b64c3297f7d1cd1d8d04e1
Autor:
Simon Houston, Ethan Schovanek, Kate M. E. Conway, Sarah Mustafa, Alloysius Gomez, Raghavendran Ramaswamy, Ayman Haimour, Martin J. Boulanger, Lisa A. Reynolds, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The etiological agent of syphilis, Treponema pallidum ssp. pallidum, is a highly invasive “stealth” pathogen that can evade the host immune response and persist within the host for decades. This obligate human pathogen is adept at establishing in
Externí odkaz:
https://doaj.org/article/6d731f08041b463f9a7832f694f354d6
Autor:
Karen V. Lithgow, Emily Tsao, Ethan Schovanek, Alloysius Gomez, Leigh Anne Swayne, Caroline E. Cameron
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the mechanisms associated with T. pallidum traversal of endothelial barriers
Externí odkaz:
https://doaj.org/article/41389e2999cf459f9ab5ccc3962512a1
Autor:
Karen V. Lithgow, Brigette Church, Alloysius Gomez, Emily Tsao, Simon Houston, Leigh Anne Swayne, Caroline E. Cameron
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Treponema pallidum subsp. pallidum is the causative agent of syphilis, a human-specific sexually transmitted infection that causes a multistage disease with diverse clinical manifestations. Treponema pallidum undergoes rapid vascular dissemi
Externí odkaz:
https://doaj.org/article/57571949b48c4a86af8ec569bcdf5b56
Autor:
Sheila A. Lukehart, Barbara Molini, Alloysius Gomez, Charmie Godornes, Rebecca Hof, Mark C. Fernandez, Ragan A. Pitner, Sean A. Gray, Darrick Carter, Lorenzo Giacani, Caroline E. Cameron
Publikováno v:
Vaccine. 40(52)
Syphilis continues to be a significant public health concern worldwide. The disease is endemic in many low- and middle-income countries, and rates have risen sharply in high-income countries over the last decade. The continued prevalence of infectiou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9042880825ce17872ec298d69fbb071
https://pubmed.ncbi.nlm.nih.gov/36376214
https://pubmed.ncbi.nlm.nih.gov/36376214
Autor:
Robert E. W. Hancock, Karen V. Lithgow, Alloysius Gomez, Caroline E. Cameron, Amy S. Lee, K Conway, S Waugh, J Fleetwood, A Eshghi
Publikováno v:
Oral presentations.
Background Treponema pallidum ssp. pallidum (Tp), the causative agent of syphilis, is a highly invasive pathogen that moves throughout the body via the bloodstream and invades organs and tissues to cause the serious sequelae associated with sexually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de32019f0274a8fb5053bc64fb7aeae
https://doi.org/10.1136/sextrans-2021-sti.50
https://doi.org/10.1136/sextrans-2021-sti.50
Autor:
Alloysius Gomez, Martin J. Boulanger, Caroline E. Cameron, A Haimour, Raghavendran Ramaswamy, S Mustafa, E Schovanek, L Reynolds, K Conway, Simon Houston
Publikováno v:
Oral presentations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d3013abc8f188384aa1b485bf7ebb6
https://doi.org/10.1136/sextrans-2021-sti.48
https://doi.org/10.1136/sextrans-2021-sti.48
Autor:
Simon Houston, Alloysius Gomez, Leigh Anne Swayne, Karen V. Lithgow, Brigette Church, Emily Tsao, Caroline E. Cameron
Publikováno v:
mSphere
mSphere, Vol 5, Iss 2 (2020)
mSphere, Vol 5, Iss 2, p e00195-20 (2020)
mSphere, Vol 5, Iss 2 (2020)
mSphere, Vol 5, Iss 2, p e00195-20 (2020)
Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subsp. pallidum. The continued incidence of syphilis demonstrates that screening and treatment strategies are not sufficient to curb this infectious di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ba514e8e9529ed3ca02fb1bb6e674d
http://europepmc.org/articles/PMC7113585
http://europepmc.org/articles/PMC7113585
Autor:
Morteza Razavi, N. Leigh Anderson, Alloysius Gomez, Kara Osbak, Simon Houston, Richard Yip, Christopher J. Kenyon, Terry W. Pearson, Caroline E. Cameron
Publikováno v:
Oral Presentations.
Background Current serology-based, treponemal-specific diagnostic tests detect antibodies reactive against T. pallidum molecules and cannot differentiate between past and current syphilis infections. Further, existing diagnostic tests for syphilis ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0288d4730c95b2e4ebbbcd5ceb285ef5
https://doi.org/10.1136/sextrans-2019-sti.117
https://doi.org/10.1136/sextrans-2019-sti.117