Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Alloantigen recognition"'
Autor:
Naoya Iwahara, Kiyohiko Hotta, Daiki Iwami, Tatsu Tanabe, Yuka Tanaka, Yoichi M. Ito, Takuya Otsuka, Sachiyo Murai, Yusuke Takada, Haruka Higuchi, Hajime Sasaki, Takayuki Hirose, Hiroshi Harada, Nobuo Shinohara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Donor-specific antibodies (DSAs) are the main cause of graft loss over time. The direct pathway of alloantigen recognition is important in the pathogenesis of acute rejection. Recent studies have suggested that the direct pathway also contributes to
Externí odkaz:
https://doaj.org/article/a1f384890ea3471c82af9657ddfe3c80
Akademický článek
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Publikováno v:
The Journal of Immunology. 201:3167-3174
Early human allograft rejection can be initiated when circulating human host versus graft Ag-specific CD8 and CD4 effector memory T cells directly recognize MHC class I and II, respectively, expressed on the luminal surface by endothelium lining graf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52fa88fdd3716718cbcf09ecaf6c615
https://doi.org/10.4049/jimmunol.1800223
https://doi.org/10.4049/jimmunol.1800223
Autor:
Kikumi S. Ozaki, Donna B. Stolz, Shinichiro Yokota, David A. Geller, Noriko Murase, Shinya Ueki, Shoko Kimura, Matthew Zhang
Publikováno v:
Liver Transplantation. 22:80-90
Hepatic ischemia/reperfusion injury (IRI) remains a major clinical problem and involves the innate immune system's recognition of “nonself.” Considering the efficient nonself recognition by natural killer (NK) cells, we hypothesize in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2a0d225f8d196993a83bfb3a69f8a3
https://doi.org/10.1002/lt.24330
https://doi.org/10.1002/lt.24330
Publikováno v:
Immunobiology. 220:1227-1231
Pattern recognition receptors (PRRs) play an important role in host anti-donor responses to transplanted tissue. A key trigger of the host alloresponse involves recognition of foreign antigen presented on activated antigen presenting cells by the hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8835238f65e1752b27694b7cb10754e0
https://doi.org/10.1016/j.imbio.2015.06.011
https://doi.org/10.1016/j.imbio.2015.06.011
Autor:
Scott McEwen, Qizhi Tang
Receiving a kidney transplant currently requires patients to commit to life-long immunosuppression therapy. The combination of immunosuppressive drugs currently taken by transplant recipients often does achieve the right degree of immunosuppression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ce134eaa8c473c07b57bc72bdd1c42
https://doi.org/10.1016/b978-0-12-801734-0.00023-0
https://doi.org/10.1016/b978-0-12-801734-0.00023-0
Autor:
Jon H. Ritter, Kelsey Toth, Daniel Kreisel, Ryuiji Higashikubo, Hollyce Hartzler, Mikhail Y. Berezin, Alexander S. Krupnick, Wenjun Li, Xue Lin, Bernd H. Zinselmeyer, Mark J. Miller, Steven T. Wang, Andrew E. Gelman
Publikováno v:
Journal of Clinical Investigation. 124:1130-1143
Memory T lymphocytes are commonly viewed as a major barrier for long-term survival of organ allografts and are thought to accelerate rejection responses due to their rapid infiltration into allografts, low threshold for activation, and ability to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1311f1cc2c9fa67b08b59dbcf610083b
https://doi.org/10.1172/jci71359
https://doi.org/10.1172/jci71359
Autor:
Gerald Brandacher, Madeline Fryer, Byoung Chol Oh, W. P. Andrew Lee, Cheng-Hung Lin, Giorgio Raimondi, Johanna Grahammer, Georg J. Furtmüller, Robert Sucher
Publikováno v:
Journal of Visualized Experiments.
In vivo animal model systems, and in particular mouse models, have evolved into powerful and versatile scientific tools indispensable to basic and translational research in the field of transplantation medicine. A vast array of reagents is available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291572bdbb3326e467206f692dcf7505
https://doi.org/10.3791/53483-v
https://doi.org/10.3791/53483-v
Autor:
Igor Tudorache, Gregor Warnecke, Fabio Ius, Jawad Salman, Nathalie Frank, Christine S. Falk, Thierry Siemeni, Danny Jonigk, Murat Avsar, Ulrich A. Maus, Axel Haverich, Katharina Jansson, Wiebke Sommer, Nodir Madrahimov, Ann-Kathrin Knöfel, G. Büchler
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 16(11)
Experimentally, regulatory T cells inhibit rejection. In clinical transplantations, however, it is not known whether T cell regulation is the cause for, or an epiphenomenon of, long-term allograft survival. Here, we study naive and alloantigen-primed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce98a039b074d3010c3f0d7f09733e2
https://pubmed.ncbi.nlm.nih.gov/27273729
https://pubmed.ncbi.nlm.nih.gov/27273729
Publikováno v:
Transplantation Proceedings. 41:4316-4320
Acute allograft rejection (AR) remains a major problem in solid organ transplantation. The pivotal mechanism hinges on alloantigen recognition by recipient T helper (T(h)) cells that differentiate into T(h)1 and T(h)2. This study investigated the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777dfd0a9607f71a558a68abd77f6835
https://doi.org/10.1016/j.transproceed.2009.08.057
https://doi.org/10.1016/j.transproceed.2009.08.057