Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Allison Sowa"'
Autor:
Brett A. Eyford, Maciej J. Lazarczyk, Kyung Bok Choi, Merina Varghese, Hitesh Arora, Suresh Kari, Lonna Munro, Cheryl G. Pfeifer, Allison Sowa, Daniel R. Dickstein, Dara L. Dickstein, Wilfred A. Jefferies
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The interplay between AMPA-type glutamate receptors (AMPARs) and major histocompatibility complex class I (MHC-I) proteins in regulating synaptic signaling is a crucial aspect of central nervous system (CNS) function. In this study, we inves
Externí odkaz:
https://doaj.org/article/b13129d68b9c4a1ab46349a7afd15b09
Autor:
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, Allison Sowa, Timothy Tetreault, Merina Varghese, David G. Cook, Carolyn W. Zhu, Susan J. Tappan, William G. M. Janssen, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract In the course of military operations in modern war theaters, blast exposures are associated with the development of a variety of mental health disorders associated with a post-traumatic stress disorder-related features, including anxiety, im
Externí odkaz:
https://doaj.org/article/0a667140f9af4965b012a6d8d6b76eae
Autor:
Maciej J. Lazarczyk, Brett A. Eyford, Merina Varghese, Hitesh Arora, Lonna Munro, Tahia Warda, Cheryl G. Pfeifer, Allison Sowa, Daniel R. Dickstein, Timothy Rumbell, Wilfred A. Jefferies, Dara L. Dickstein
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Major histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown. Here we describe the first structural a
Externí odkaz:
https://doaj.org/article/efb7fabefb7e4b9fb5bff7fbd1571479
Autor:
Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Katia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, J. Oriol Narcis, Shilpa Dilip Kumar, William Janssen, Allison Sowa, Giacomo P. Comi, Alessio Di Fonzo, John F. Crary, Steven J. Frucht, Towfique Raj
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Background Genetic mutations in beta-glucocerebrosidase (GBA) represent the major genetic risk factor for Parkinson’s disease (PD). GBA participates in both the endo-lysosomal pathway and the immune response, two important mechanisms invol
Externí odkaz:
https://doaj.org/article/dbe17cf7cdea4ab8b6a5e2418d509f7c
Autor:
Margaret Krassner, Justin Kauffman, Allison Sowa, Katarzyna Cialowicz, Samantha Walsh, Kurt Farrell, John Crary, Andrew McKenzie
Publikováno v:
Free Neuropathology, Vol 4 (2023)
Brain cell structure is a key determinant of neural function that is frequently altered in neurobiological disorders. Following the global loss of blood flow to the brain that initiates the postmortem interval (PMI), cells rapidly become depleted of
Externí odkaz:
https://doaj.org/article/859fafbf717f4509859bc3a94befd4bd
Autor:
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, William G. Janssen, Allison Sowa, Timothy Tetreault, David G. Cook, Susan J. Tappan, Sam Gandy, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-27 (2021)
Abstract Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is primarily the result of blast wave-induced mechanical disruptions within the neurovascular unit. In rodent models of blast-induced traumatic brain injury, c
Externí odkaz:
https://doaj.org/article/ab5d8f1892bb40219c7b39ff4c4f768e
Autor:
Balaji Krishnan, Chandramouli Natarajan, Krystyn Z. Bourne, Leila Alikhani, Juan Wang, Allison Sowa, Katherine Groen, Bayley Perry, Dara L. Dickstein, Janet E. Baulch, Charles L. Limoli, Richard A. Britten
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3668 (2021)
The proposed deep space exploration to the moon and later to Mars will result in astronauts receiving significant chronic exposures to space radiation (SR). SR exposure results in multiple neurocognitive impairments. Recently, our cross-species (mous
Externí odkaz:
https://doaj.org/article/0c06f40d7104429c89de546fdd6dc4c0
Autor:
Brett A. Eyford, Maciej J. Lazarczyk, Merina Varghese, Kyung Bok Choi, Hitesh Arora, Lonna Munro, Cheryl G. Pfeifer, Allison Sowa, Daniel R. Dickstein, Dara L. Dickstein, Wilfred A. Jefferies, Suresh Kari
AMPA-type glutamate receptors (AMPARs) and major histocompatibility complex class I (MHC-I) proteins regulate synaptic signalling. Here we describe the importance of the cytoplasmic tail of MHC-I for its role in the central nervous system (CNS) in sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84d1522dfa80897de7a508a74fb3735
https://doi.org/10.21203/rs.3.rs-2699534/v1
https://doi.org/10.21203/rs.3.rs-2699534/v1
Autor:
Scott Russo, Flurin Cathomas, Hsiao-yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murrough
Psychosocial stress has profound effects on the body, including the peripheral immune system and the brain1,2. Although a large number of pre-clinical and clinical studies have linked peripheral immune system alterations to stress-related disorders s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c4c5f4f941779901d8849faeb60f52
https://doi.org/10.21203/rs.3.rs-1647827/v1
https://doi.org/10.21203/rs.3.rs-1647827/v1
Autor:
Maciej J. Lazarczyk, Brett A. Eyford, Merina Varghese, Hitesh Arora, Lonna Munro, Tahia Warda, Cheryl G. Pfeifer, Allison Sowa, Daniel R. Dickstein, Timothy Rumbell, Wilfred Jefferies, Dara Dickstein
Major histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown. Here we describe the first structural analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6cd3134e7f020bc3498727844cd0078
https://doi.org/10.21203/rs.3.rs-2057879/v1
https://doi.org/10.21203/rs.3.rs-2057879/v1