Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Allison Simpson"'
Publikováno v:
Journal of Mental Health Research in Intellectual Disabilities. 15:253-262
Autor:
John R. MacDougall, Raymond Mak, John Bradley, Allison Simpson, Claire May, Lan Wei, Kendra Ouellette, Marty Olbrot, Jimmy Blair, Neil Dhawan, Wei Chen
Publikováno v:
Cancer Research. 83:2249-2249
TOS-358 is a first-in-class covalent inhibitor of PI3Kα and is currently in clinical development in a variety of solid malignancies. We have developed a fit-for-purpose pharmacodynamic assay to evaluate the target occupancy of TOS-358 in in vitro an
Publikováno v:
Nutrition and Health. :026010602211490
Low-carbohydrate, high-fat (LCHF) nutrition therapy is characterized by carbohydrates comprising
Autor:
Jennifer A. Dumont, Gaurav Manohar Rajani, Joe Salas, Robert T. Peters, Kate Henry, Allison Simpson, Katalin Kis-Toth, Christine Loh
Publikováno v:
Blood Advances. 2:2904-2916
The main complication of replacement therapy with factor in hemophilia A (HemA) is the formation of inhibitors (neutralizing anti–factor VIII [FVIII] antibodies) in ∼30% of severe HemA patients. Because these inhibitors render replacement FVIII t
Autor:
Nicole Danek, Ashish Kalra, Stefan Wawersik, Ryan R. Faucette, Gregory J. Carven, Constance Martin, Alan Buckler, Anastasia Nikiforov, Frederick C. Streich, Christopher Brueckner, Pichai Raman, Lin Susan, Kevin B. Dagbay, Christopher Littlefield, Justin W. Jackson, Christopher Chapron, Francis T. Danehy, Thomas Schurpf, Christopher Boston, Allison Simpson, Abhishek Datta, Capili Allan
Publikováno v:
Science Translational Medicine. 12
Despite breakthroughs achieved with cancer checkpoint blockade therapy (CBT), many patients do not respond to anti-programmed cell death-1 (PD-1) due to primary or acquired resistance. Human tumor profiling and preclinical studies in tumor models hav
Autor:
Sara K. Mamo, Olivia Nirmalasari, Carrie L. Nieman, Allison Simpson, Matthew K. McNabney, Frank R. Lin, Esther S. Oh
Publikováno v:
The American Journal of Geriatric Psychiatry. 25:91-101
Objective Hearing loss is a commonly unmet need among adults with dementia that may exacerbate common dementia-related behavioral symptoms. Accessing traditional audiology services for hearing loss is a challenge because of high cost and time commitm
Autor:
Allison Simpson, Jessica Zimmerman, Sara K. Mamo, Esther S. Oh, Carrie L. Nieman, Olivia Nirmalasari, Milap A. Nowrangi, Frank R. Lin
Publikováno v:
International Psychogeriatrics. 29:115-121
Background:Hearing loss can impair effective communication between caregivers and individuals with cognitive impairment. However, hearing loss is not often measured or addressed in care plans for these individuals. The aim of this study is to measure
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Autor:
Maurice Hains, Kimberly Holte, Amit Choudhury, Daniel Ortiz, Christopher Beneduce, Jonathan C. Lansing, Thomas Prod’homme, Steven Tyler, Robert Prenovitz, Lynn Markowitz, Elma Kurtagic, Allison Simpson, Laura I. Rutitzky, Julia Brown, Leona E. Ling, Stephanie Nguyen, Birgit Schultes, Ishan Capila, Anthony M. Manning, Robin Meccariello, Inessa Schwab, Nathaniel Washburn, Carlos J. Bosques, Matthew A. Child, Radouane Zouaoui, Jason Killough, Falk Nimmerjahn, Jing Wang, Naveen Bhatnagar
Publikováno v:
Science Translational Medicine. 8
Autoantibody immune complex (IC) activation of Fcγ receptors (FcγRs) is a common pathogenic hallmark of multiple autoimmune diseases. Given that the IC structural features that elicit FcγR activation are poorly understood and the FcγR system is h
Autor:
Christopher Littlefield, Ashish Kalra, Anastasia Nikiforov, Christopher Boston, Allison Simpson, Constance Martin, Stefan Wawersik, Abhishek Datta, Christopher Chapron, Francis T. Danehy, Thomas Schurpf, Gregory J. Carven, Lin Susan, Justin W. Jackson, Alan Buckler
Publikováno v:
Cancer Research. 79:4090-4090
Despite the clinical breakthroughs achieved by checkpoint blockade therapy (CBT), a majority of patients treated with PD-(L)1 inhibitors fail to respond due to primary or acquired resistance. TGFβ signaling has recently been implicated as a mechanis