Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Allison S. Landman"'
Autor:
Abraham Acevedo-Arozena, Steve D.M. Brown, Henning Wackerhage, Michelle Simon, Jessica Wettstein, Saumya Kumar, Vassilios N. Kotiadis, Debbie Williams, David C. Rubinsztein, Thomas Agnew, Lee Moir, Allison S. Landman, Michael R. Duchen, Silvia Corrochano, Michelle Stewart, Gonzalo Blanco
Publikováno v:
Journal of Experimental Neuroscience
Human Molecular Genetics
Human Molecular Genetics, 27 (10)
Human Molecular Genetics
Human Molecular Genetics, 27 (10)
Polyglutamine expansions in the huntingtin gene cause Huntington’s disease (HD). Huntingtin is ubiquitously expressed, leading to pathological alterations also in peripheral organs. Variations in the length of the polyglutamine tract explain up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a92b2cf42ea56ab3b1a3a182d491d28
Autor:
Allison S. Landman, Julie C. West, Roderick T. Bronson, Siddhartha Mukherjee, Borel Djouedjong Fonhoue, Alicia M. Caron, Seth D. Berman, Eliezer Calo, Emily S. Miller, Mary L. Bouxsein, Jacqueline A. Lees, Paul S. Danielian
Publikováno v:
Proceedings of the National Academy of Sciences. 105:11851-11856
Mutation of the RB-1 and p53 tumor suppressors is associated with the development of human osteosarcoma. With the goal of generating a mouse model of this disease, we used conditional and transgenic mouse strains to inactivate Rb and/or p53 specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e995e563073a9ad7df56ef7be6360b1
https://doi.org/10.1073/pnas.0805462105
https://doi.org/10.1073/pnas.0805462105
Publikováno v:
Genetics. 179:199-211
In wild-type diploid cells, heteroallelic recombination between his4A and his4C alleles leads mostly to His+ gene conversions that have a parental configuration of flanking markers, but ∼22% of recombinants have associated reciprocal crossovers. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c320e6fb5e93deab1a28c1e76f90390
https://doi.org/10.1534/genetics.108.087189
https://doi.org/10.1534/genetics.108.087189
Publikováno v:
PMC
The pocket proteins pRB, p107 and p130 have established roles in regulating the cell cycle through the control of E2F activity. The pocket proteins regulate differentiation of a number of tissues in both cell cycle-dependent and -independent manners.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bff40367eee9a3b997b75a488b4e40
https://europepmc.org/articles/PMC3931423/
https://europepmc.org/articles/PMC3931423/