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pro vyhledávání: '"Allison Robyn Pettit"'
Induction of osteoblast apoptosis stimulates macrophage efferocytosis and paradoxical bone formation
Autor:
Lena Batoon, Amy Jean Koh, Susan Marie Millard, Jobanpreet Grewal, Fang Ming Choo, Rahasudha Kannan, Aysia Kinnaird, Megan Avey, Tatyana Teslya, Allison Robyn Pettit, Laurie K. McCauley, Hernan Roca
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Apoptosis is crucial for tissue homeostasis and organ development. In bone, apoptosis is recognized to be a main fate of osteoblasts, yet the relevance of this process remains underexplored. Using our murine model with inducible Caspase 9, t
Externí odkaz:
https://doaj.org/article/abd454a427604aa5b62e4982e2b7c321
Autor:
Lena, Batoon, Susan Marie, Millard, Martin Eduard, Wullschleger, Corina, Preda, Andy Chiu-Ku, Wu, Simranpreet, Kaur, Hsu-Wen, Tseng, David Arthur, Hume, Jean-Pierre, Levesque, Liza Jane, Raggatt, Allison Robyn, Pettit
Publikováno v:
Biomaterials. 196
Osteal macrophages (osteomacs) contribute to bone homeostasis and regeneration. To further distinguish their functions from osteoclasts, which share many markers and growth factor requirements, we developed a rapid, enzyme-free osteomac enrichment pr