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pro vyhledávání: '"Allison R. Reid"'
Autor:
Jason J. McDougall, Allison R. Reid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Joint pain is a complex phenomenon that involves multiple endogenous mediators and pathophysiological events. In addition to nociceptive and inflammatory pain, some patients report neuropathic-like pain symptoms. Examination of arthritic joints from
Externí odkaz:
https://doaj.org/article/8702464cfd724ac38870566e3107c99b
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1571 (2022)
The voltage gated sodium channels (Nav) 1.7, 1.8, and 1.9 are primarily located on nociceptors where they are involved in signalling neuropathic pain. This study examined the effect of Nav1.7 blockade on joint pain using either the small molecule inh
Externí odkaz:
https://doaj.org/article/db913d02dadc491e9f0a048246c85806
Autor:
Jason J. McDougall, Allison R. Reid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Joint pain is a complex phenomenon that involves multiple endogenous mediators and pathophysiological events. In addition to nociceptive and inflammatory pain, some patients report neuropathic-like pain symptoms. Examination of arthritic joints from
Autor:
Milind M, Muley, Allison R, Reid, Bálint, Botz, Kata, Bölcskei, Zsuzsanna, Helyes, Jason J, McDougall
Publikováno v:
British journal of pharmacology. 173(4)
Neutrophil elastase plays a crucial role in arthritis. Here, its potential in triggering joint inflammation and pain was assessed, and whether these effects were mediated by proteinase-activated receptor-2 (PAR2).Neutrophil elastase (5 μg) was injec
Publikováno v:
European journal of pharmacology. 714(1-3)
Tramadol, an analgesic used alone or combined with acetaminophen, has a complex mechanism of action involving opioid and amine mechanisms. In this study, we explored the involvement of spinal and peripheral adenosine A1 receptors in antinociception b
Autor:
Jana, Sawynok, Allison R, Reid
Publikováno v:
European journal of pharmacology. 674(2-3)
The present study examined effects of caffeine on antinociception by acetaminophen in the formalin test in mice. It demonstrates that caffeine 10mg/kg inhibits antinociception produced by acetaminophen 300 mg/kg i.p. against phase 2 flinches. Chronic