Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Allison R. Greenplate"'
Autor:
Guanning Wang, Olga Lyudovyk, Justin Y. Kim, Ya-Hui Lin, Yuval Elhanati, Divij Mathew, E. John Wherry, Ramin S. Herati, Allison R. Greenplate, Benjamin Greenbaum, Santosha A. Vardhana, Alexander C. Huang
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102289- (2023)
Summary: The current abundance of immunotherapy clinical trials presents an opportunity to learn about the underlying mechanisms and pharmacodynamic effects of novel drugs on the human immune system. Here, we present a protocol to study how these imm
Externí odkaz:
https://doaj.org/article/ceb6358ee28f40d0803f2776252de89a
Autor:
Alexandre Nicolas, Gérémy Sannier, Mathieu Dubé, Manon Nayrac, Alexandra Tauzin, Mark M. Painter, Rishi R. Goel, Mélanie Laporte, Gabrielle Gendron-Lepage, Halima Medjahed, Justine C. Williams, Nathalie Brassard, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Cécile Tremblay, Valérie Martel-Laferrière, Andrés Finzi, Allison R. Greenplate, E. John Wherry, Daniel E. Kaufmann
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105904- (2023)
Summary: Spacing the first two doses of SARS-CoV-2 mRNA vaccines beyond 3–4 weeks raised initial concerns about vaccine efficacy. While studies have since shown that long-interval regimens induce robust antibody responses, their impact on B and T c
Externí odkaz:
https://doaj.org/article/cb87a511664f4979acf3c0bb560c1dde
Autor:
Christopher V. Cosgriff, MD, MPH, Todd A. Miano, PhD, PharmD, Divij Mathew, PhD, Alexander C. Huang, MD, PhD, Heather M. Giannini, MD, MS, Leticia Kuri-Cervantes, PhD, M. Betina Pampena, PhD, Caroline A. G. Ittner, PhD, Ariel R. Weisman, MS, Roseline S. Agyekum, BS, Thomas G. Dunn, BS, Oluwatosin Oniyide, BS, Alexandra P. Turner, BS, Kurt D’Andrea, BS, Sharon Adamski, BS, Allison R. Greenplate, PhD, Brian J. Anderson, MD, MSCE, Michael O. Harhay, PhD, Tiffanie K. Jones, MD, MPH, MSCE, John P. Reilly, MD, MSCE, Nilam S. Mangalmurti, MD, Michael G. S. Shashaty, MD, MSCE, Michael R. Betts, PhD, E. John Wherry, PhD, Nuala J. Meyer, MD, MS
Publikováno v:
Critical Care Explorations, Vol 4, Iss 12, p e0800 (2022)
OBJECTIVES:. COVID-19 is a heterogenous disease. Biomarker-based approaches may identify patients at risk for severe disease, who may be more likely to benefit from specific therapies. Our objective was to identify and validate a plasma protein signa
Externí odkaz:
https://doaj.org/article/987a6075e22c4b8b8c873ee3a0bd699e
Autor:
Sokratis A. Apostolidis, Amrita Sarkar, Heather M. Giannini, Rishi R. Goel, Divij Mathew, Aae Suzuki, Amy E. Baxter, Allison R. Greenplate, Cécile Alanio, Mohamed Abdel-Hakeem, Derek A. Oldridge, Josephine R. Giles, Jennifer E. Wu, Zeyu Chen, Yinghui Jane Huang, Jonathan Belman, Ajinkya Pattekar, Sasikanth Manne, Oliva Kuthuru, Jeanette Dougherty, Brittany Weiderhold, Ariel R. Weisman, Caroline A. G. Ittner, Sigrid Gouma, Debora Dunbar, Ian Frank, Alexander C. Huang, Laura A. Vella, The UPenn COVID Processing Unit, John P. Reilly, Scott E. Hensley, Lubica Rauova, Liang Zhao, Nuala J. Meyer, Mortimer Poncz, Charles S. Abrams, E. John Wherry, Sharon Adamski, Zahidul Alam, Mary M. Addison, Katelyn T. Byrne, Aditi Chandra, Hélène C. Descamps, Nicholas Han, Yaroslav Kaminskiy, Shane C. Kammerman, Justin Kim, Jacob T. Hamilton, Nune Markosyan, Julia Han Noll, Dalia K. Omran, Eric Perkey, Elizabeth M. Prager, Dana Pueschl, Austin Rennels, Jennifer B. Shah, Jake S. Shilan, Nils Wilhausen, Ashley N. Vanderbeck
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflamm
Externí odkaz:
https://doaj.org/article/f380b6f884834140a346b9249d88cbb6
Autor:
Benjamin Kahn, BA, Sokratis A. Apostolidis, MD, Vatsal Bhatt, MD, Allison R. Greenplate, PhD, Staci Kallish, DO, Anthony LaCava, MD, Alfredo Lucas, BA, Nuala J. Meyer, MD, MS, Dan Negoianu, MD, Alexis R. Ogdie, MD, MSCE, Michael G. S. Shashaty, MD, MSCE, Patricia A. Takach, MD, Leah Zuroff, MD, MS, E. John Wherry, PhD, George L. Anesi, MD, MSCE, MBE
Publikováno v:
Critical Care Explorations, Vol 3, Iss 11, p e0578 (2021)
BACKGROUND:. The U.S. Food and Drug Administration has to date granted approval or emergency use authorization to three vaccines against severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019. In clinical trials and real-use obs
Externí odkaz:
https://doaj.org/article/2bf181e5ca184060a76eb3a8b345f61c
Autor:
Douglas B. Johnson, Monica V. Estrada, Roberto Salgado, Violeta Sanchez, Deon B. Doxie, Susan R. Opalenik, Anna E. Vilgelm, Emily Feld, Adam S. Johnson, Allison R. Greenplate, Melinda E. Sanders, Christine M. Lovly, Dennie T. Frederick, Mark C. Kelley, Ann Richmond, Jonathan M. Irish, Yu Shyr, Ryan J. Sullivan, Igor Puzanov, Jeffrey A. Sosman, Justin M. Balko
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Immunotherapy is used to treat melanoma, however patient responses vary widely highlighting the need for factors that can predict therapeutic success. Here, the authors show that MHC-II molecules expressed by tumour cells are positively correlated wi
Externí odkaz:
https://doaj.org/article/459810ce61c5459985557e37a55f8eed
Autor:
Nalin Leelatian, Justine Sinnaeve, Akshitkumar M Mistry, Sierra M Barone, Asa A Brockman, Kirsten E Diggins, Allison R Greenplate, Kyle D Weaver, Reid C Thompson, Lola B Chambless, Bret C Mobley, Rebecca A Ihrie, Jonathan M Irish
Publikováno v:
eLife, Vol 9 (2020)
A goal of cancer research is to reveal cell subsets linked to continuous clinical outcomes to generate new therapeutic and biomarker hypotheses. We introduce a machine learning algorithm, Risk Assessment Population IDentification (RAPID), that is uns
Externí odkaz:
https://doaj.org/article/4b0f2febcca2420290d9f64856a5a58a
Autor:
Jonathan M. Irish, P. Brent Ferrell, Igor Puzanov, Jeffrey A. Sosman, Michael R. Savona, Mikael Roussel, Douglas B. Johnson, Allison R. Greenplate
Mass cytometry panel of antibodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fd2719e6a2ee6939160d2eba9cc8b8
https://doi.org/10.1158/2326-6066.22538641.v1
https://doi.org/10.1158/2326-6066.22538641.v1
Autor:
Jonathan M. Irish, Douglas B. Johnson, P. Brent Ferrell, Jeffrey C. Rathmell, Peter J. Siska, Vivian Gama, Mark C. Kelley, Megan L. Rasmussen, Nalin Leelatian, Kirsten E. Diggins, Caroline E. Roe, Deon B. Doxie, Brian K. Oberholtzer, Daniel D. McClanahan, Allison R. Greenplate
Supplementary table containing the mass cytometry staining panels used in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d425210f8898f5f37a5797327495d78
https://doi.org/10.1158/2326-6066.22536506
https://doi.org/10.1158/2326-6066.22536506
Autor:
Jonathan M. Irish, P. Brent Ferrell, Igor Puzanov, Jeffrey A. Sosman, Michael R. Savona, Mikael Roussel, Douglas B. Johnson, Allison R. Greenplate
Antibodies aimed at blocking the interaction between programmed cell death-1 (PD-1) and its ligands have shown impressive efficacy in a variety of malignancies and are generally well tolerated. Research has focused intensely on T cells and their inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501110dc5593f6907b403503cc5aee65
https://doi.org/10.1158/2326-6066.c.6548842.v1
https://doi.org/10.1158/2326-6066.c.6548842.v1