Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Allison Noe"'
Autor:
Hetty E. Carraway, Cassandra M Kerr, Hassan Awada, Allison Noe, Yuriy Fedorov, Steffan T. Nawrocki, Daniel J. Lindner, Heesun J. Rogers, Bartlomiej P Przychodzen, Anjali S. Advani, Yvonne Parker, Kevin R. Kelly, James G. Phillips, Vera Adema, Rachel Toth, Valeria Visconte, Drew J. Adams, Anand D. Tiwari, Jennifer S. Carew, Mikkael A. Sekeres, Christina Snider, Jaroslaw P. Maciejewski
Publikováno v:
Blood. 134:564-564
SF3B1 mutations disrupt normal pre-mRNA splicing to cause disease. Drugs inhibiting the interaction between the SF3b complex and RNA or agents degrading auxiliary splicing factors are being tested as new avenues for targeted therapy in myeloid neopla
Autor:
Hetty E. Carraway, Allison Noe, Vera Adema, Drew J. Adams, Bartlomiej P Przychodzen, Yvonne Parker, Daniel J. Lindner, Steffan T. Nawrocki, Tomas Radivoyevitch, Kevin R. Kelly, Mikkael A. Sekeres, Yuriy Fedorov, Richard A. Padgett, Hassan Awada, Cassandra M. Hirsch, Rachel Toth, Jaroslaw P. Maciejewski, Valeria Visconte, James G. Phillips, Heesun J. Rogers, Amy C Graham, Anjali S. Advani, Christina Snider, Jennifer S. Carew
Publikováno v:
Blood. 132:211-211
SF3B1 is a splicing factor gene whose mutations are pathognomonic of MDS with ring sideroblasts. Because of the ubiquitous importance of splicing, a major barrier in targeting cells with spliceosomal mutations is the discovery of agents decreasing th