Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Allison N. Seyfried"'
Autor:
Rachel Grazda, Allison N. Seyfried, Krishna Rao Maddipati, Gabrielle Fredman, Katherine C. MacNamara
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-11 (2024)
Abstract Severe aplastic anemia (SAA) is a rare, fatal disease characterized by severe cytopenias and loss of hematopoietic stem cells (HSCs). Immune-mediated destruction and inflammation are known drivers of SAA, however, the underlying mechanisms d
Externí odkaz:
https://doaj.org/article/a27dbae5c77943b1ad40509dd8e299b8
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The bone marrow contains distinct cell types that work in coordination to generate blood and immune cells, and it is the primary residence of hematopoietic stem cells (HSCs) and more committed multipotent progenitors (MPPs). Even at homeostasis the b
Externí odkaz:
https://doaj.org/article/519e9a22f20245be93ef5bdb4650b85a
Autor:
Rachel Grazda, Allison N. Seyfried, Krishna Rao Maddipatti, Gabrielle Fredman, Katherine C. MacNamara
Severe aplastic anemia (SAA) is an acquired form of bone marrow failure characterized by a profound loss of hematopoietic stem cells and failure to produce blood and immune cells. T cells are well-known drivers of disease, though underlying mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f57a25e90983a05930253d2a8f63247c
https://doi.org/10.1101/2023.02.15.528688
https://doi.org/10.1101/2023.02.15.528688
Autor:
Matthew Spite, Jennifer Howard, Zeinab F. Hosseini, Sudeshna Sadhu, Michael Marinello, Allison N. Seyfried, Masayuki Mori, Aloke V. Finn, John M. Lamar, Gabrielle Fredman, Brian E. Sansbury, David Jourd'heuil, Thilaka Arunachalam, Liang Guo, Christa Decker, Katherine C. MacNamara
Publikováno v:
J Immunol
Radiation is associated with tissue damage and increased risk of atherosclerosis, but there are currently no treatments and a very limited mechanistic understanding of how radiation impacts tissue repair mechanisms. We uncovered that radiation signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96899d040b266eab1f7ceae80b8f11f7
https://europepmc.org/articles/PMC8555670/
https://europepmc.org/articles/PMC8555670/
Autor:
Zeinab F. Hosseini, John M. Lamar, Gabrielle Fredman, Aloke V. Finn, Allison N. Seyfried, Brian E. Sansbury, Matthew Spite, Thilaka Arunachalam, Liang Guo, Masayuki Mori, Sudeshna Sadhu, David Jourd'heuil, Michael Marinello, Jennifer Howard, Christa Decker, Katherine C. MacNamara
Radiation is associated with tissue damage and increased risk of atherosclerosis but there are currently no treatments and a very limited mechanistic understanding of how radiation impacts tissue repair mechanisms. We uncovered that radiation signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3258c147cd64bcce16c136a3b12d87d
https://doi.org/10.1101/2021.05.19.444879
https://doi.org/10.1101/2021.05.19.444879
Autor:
Julianne N.P. Smith, Katherine C. MacNamara, Allison N. Seyfried, Amanda McCabe, Laura M. Calvi
Publikováno v:
Leukemia
Severe aplastic anemia (SAA) is an acquired, T cell-driven bone marrow (BM) failure disease characterized by elevated interferon gamma (IFNγ), loss of hematopoietic stem cells (HSCs), and altered BM microenvironment, including dysfunctional macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fbc879864bce056e34b3572b654dd3
https://pubmed.ncbi.nlm.nih.gov/33744909
https://pubmed.ncbi.nlm.nih.gov/33744909
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
The bone marrow contains distinct cell types that work in coordination to generate blood and immune cells, and it is the primary residence of hematopoietic stem cells (HSCs) and more committed multipotent progenitors (MPPs). Even at homeostasis the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceecc328367108c37890297d3a071874
https://www.frontiersin.org/article/10.3389/fimmu.2020.01499/full
https://www.frontiersin.org/article/10.3389/fimmu.2020.01499/full
Autor:
Julianne N.P. Smith, Amanda McCabe, Allison N. Seyfried, Katherine C. MacNamara, Laura M. Calvi
Publikováno v:
Experimental Hematology. 88:S45
Severe aplastic anemia (SAA) is an acquired bone marrow failure disease associated with elevated interferon-gamma (IFNγ) and hematopoietic stem cells (HSC) loss. Treatment for SAA includes immunosuppressive therapy (IST) or HSC transplant, though th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca38f0611a7fa5aa11efb344801d855d
https://doi.org/10.1016/j.exphem.2020.09.044
https://doi.org/10.1016/j.exphem.2020.09.044
Autor:
Grazda, Rachel, Seyfried, Allison N., Maddipati, Krishna Rao, Fredman, Gabrielle, MacNamara, Katherine C.
Publikováno v:
Cell Death & Disease; May2024, Vol. 15 Issue 5, p1-11, 11p
Publikováno v:
Blood Weekly; 5/30/2024, p125-125, 1p