Výsledky vyhledávání - "Allison M. Adams"

Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

Autor: Jennifer Potter, Allison M. Adams, Kathryn C. Davidson, Circe E. McDonald, Randall T. Moon, Travis L. Biechele, Russell J. Taylor, Jamie M. Goodson, Jason D. Berndt

Publikováno v: Proceedings of the National Academy of Sciences. 109:4485-4490

Signal transduction pathways play diverse, context-dependent roles in vertebrate development. In studies of human embryonic stem cells (hESCs), conflicting reports claim Wnt/β-catenin signaling promotes either self-renewal or differentiation. We use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314fe37d5621246a6116554c970c64ca
https://doi.org/10.1073/pnas.1118777109

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Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cells

Autor: Allison M. Adams, K. G. Silvério, Francisco Humberto Nociti, Randall T. Moon, Kathryn C. Davidson, Richard G. James, Brian L. Foster, Martha J. Somerman

Publikováno v: Journal of Periodontal Research. 47:309-319

Background and Objectives Bmp2-induced osteogenic differentiation has been shown to occur through the canonical Wnt/β-catenin pathway, whereas factors promoting canonical Wnt signaling in cementoblasts inhibited cell differentiation and promoted cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e30baefcb77735b29b9f76589d587a75
https://doi.org/10.1111/j.1600-0765.2011.01433.x

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An SMA Project Report: Neural Cell-Based Assays Derived from Human Embryonic Stem Cells

Autor: Soojung Shin, Patricia G. Wilson, Allison M. Adams, Jianhua Zhou, Steven L. Stice, Shelle Schwamberger, Jonathan J. Cherry

Publikováno v: Stem Cells and Development. 16:1027-1042

Human embryonic stem (ES) cells are promising resources for developing new treatments for neurodegenerative diseases. Spinal muscular atrophy (SMA) is one of the leading causes of childhood paralysis and infant mortality. SMA is caused by inactivatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d49bc0cd7153b44db33f8cb43857a68
https://doi.org/10.1089/scd.2007.0061

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Inactivation of Chibby affects function of motile airway cilia

Autor: Allison M. Adams, Vera Voronina, Barbara R. Grubb, Randall T. Moon, Feng-Qian Li, Ken-Ichi Takemaru, Adeline M. Hajjar, Damon Love, Piper M. Treuting

Publikováno v: The Journal of Cell Biology

Chibby (Cby) is a conserved component of the Wnt-beta-catenin pathway. Cby physically interacts with beta-catenin to repress its activation of transcription. To elucidate the function of Cby in vertebrates, we generated Cby(-/-) mice and found that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ab05e5e85500ce881bed0bf25d2857
https://pubmed.ncbi.nlm.nih.gov/19364920

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Transcription-Based Reporters of Wnt/β-Catenin Signaling

Autor: Allison M. Adams, Randall T. Moon, Travis L. Biechele

Publikováno v: Cold Spring Harbor Protocols. 2009:pdb.prot5223

INTRODUCTIONThe Wnt/β-catenin pathway is the best characterized Wnt pathway largely as a result of powerful assays that allow measurement of in vivo and in vitro pathway activation. Early assays for Wnt/β-catenin signaling included phenotypic assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9c79bbe27a91949e6ebfaaa0a8f7ba
https://doi.org/10.1101/pdb.prot5223

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