Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Allison M Dubner"'
Autor:
Allison M. Dubner, Sizhao Lu, Austin J. Jolly, Keith A. Strand, Marie F. Mutryn, Tyler Hinthorn, Tysen Noble, Raphael A. Nemenoff, Karen S. Moulton, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
We previously established that vascular smooth muscle–derived adventitial progenitor cells (AdvSca1-SM) preferentially differentiate into myofibroblasts and contribute to fibrosis in response to acute vascular injury. However, the role of these pro
Externí odkaz:
https://doaj.org/article/457a71ce90e84954826e313a6a63b0aa
Autor:
Austin J. Jolly, Sizhao Lu, Allison M. Dubner, Keith A. Strand, Marie F. Mutryn, Aaron Pilotti-Riley, Etienne P. Danis, Raphael A. Nemenoff, Karen S. Moulton, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Vascular smooth muscle–derived Sca1+ adventitial progenitor (AdvSca1-SM) cells are tissue-resident, multipotent stem cells that contribute to progression of vascular remodeling and fibrosis. Upon acute vascular injury, AdvSca1-SM cells differentiat
Externí odkaz:
https://doaj.org/article/f28d2456ad89429599aa18fbc319991c
Autor:
Sizhao Lu, Austin J. Jolly, Keith A. Strand, Allison M. Dubner, Marie F. Mutryn, Karen S. Moulton, Raphael A. Nemenoff, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
Resident vascular adventitial SCA1+ progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior
Externí odkaz:
https://doaj.org/article/6757c5fc0e5a449ba35f422f50f7244a
Autor:
Marie F Mutryn, Keith A. Strand, Raphael A. Nemenoff, Sizhao Lu, Austin J Jolly, Mary C.M. Weiser-Evans, Allison M. Dubner, Mark W. Majesky, Karen S. Moulton
Publikováno v:
Cardiovasc Res
Cardiovascular diseases are characterized by chronic vascular dysfunction and provoke pathological remodelling events, such as neointima formation, atherosclerotic lesion development, and adventitial fibrosis. While lineage-tracing studies have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d48b60f2adb46b9516c2486d77bc935
https://doi.org/10.1093/cvr/cvab174
https://doi.org/10.1093/cvr/cvab174
Autor:
Sizhao Lu, Austin J Jolly, Allison M Dubner, Marie F Mutryn, Raphael A Nemenoff, Karen S Moulton, Mary C Weiser-Evans
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Activated cardiac myofibroblasts are the major contributors to ECM deposition in pathological cardiovascular fibrosis, which is the characteristic feature of cardiovascular diseases. However, due to potential heterogeneity of myofibroblasts, the orig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c17e607dc7b8a4d43b5640d328b78ba
https://doi.org/10.1161/atvb.42.suppl_1.317
https://doi.org/10.1161/atvb.42.suppl_1.317
Autor:
Allison M Dubner, Sizhao Lu, Marie Mutryn, Austin Jolly, Keith Strand, Natalie Navarro, Karen Moulton, Raphael Nemenoff, Mary C Weiser-Evans
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Purpose: Atherosclerosis is a major cause of morbidity and mortality worldwide, but current therapies fail to adequately meet clinical needs. Emerging evidence implicates the outer layer of the blood vessel, the adventitia, in the pathogenesis of ath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c434df53a89a53ef0ee2bc4fb6b70236
https://doi.org/10.1161/atvb.42.suppl_1.240
https://doi.org/10.1161/atvb.42.suppl_1.240
Autor:
Qiong Zhou, Raphael A. Nemenoff, Mary C.M. Weiser-Evans, Sizhao Lu, Allison M. Dubner, Keith A. Koch, Austin J Jolly, Daniel V. LaBarbera, Blake T. Enyart, Linfeng Li, Keith A. Strand, Karen S. Moulton, Marie F Mutryn
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Our recent work demonstrates that PTEN (phosphatase and tensin homolog) is an important regulator of smooth muscle cell (SMC) phenotype. SMC-specific PTEN deletion promotes spontaneous vascular remodeling and PTEN loss correlates with incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e5542c7d38a639dc7ed07967eae1e9
https://doi.org/10.1161/atvbaha.120.314458
https://doi.org/10.1161/atvbaha.120.314458
Autor:
Mary C.M. Weiser-Evans, Allison M. Dubner, Austin J Jolly, Mark W. Majesky, Raphael A. Nemenoff, Karen S. Moulton, Marie F Mutryn, Keith A. Strand, Sizhao Lu
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
JCI Insight
JCI Insight
Resident vascular adventitial SCA1+ progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66132641d96684b2f64c5d8d7cefc591
https://doaj.org/article/6757c5fc0e5a449ba35f422f50f7244a
https://doaj.org/article/6757c5fc0e5a449ba35f422f50f7244a
Autor:
Marie F Mutryn, Austin J Jolly, Keith A. Strand, Raphael A. Nemenoff, Rebecca M. Tucker, Karen S. Moulton, Allison M. Dubner, Sizhao Lu, Mary C.M. Weiser-Evans
Publikováno v:
Journal of Clinical and Translational Science. 4:102-102
OBJECTIVES/GOALS: Our lab previously identified a population of vascular smooth muscle (SMC)-derived progenitor cells (AdvSca1-SM) which expand robustly in response to disease and can differentiate into multiple cell types. We now aim to define the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa22c15ec5522655d7bb401f74daa016
https://doi.org/10.1017/cts.2020.315
https://doi.org/10.1017/cts.2020.315