Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Allison Loehr"'
Autor:
Paul Au, Raymond S. Yeung, G. Scott Herron, Cynthia Cohen, David E. Fisher, David H. Gutmann, Sharon W. Weiss, Jiwei Yang, Mahul B. Amin, David A. Frank, Ian J. Davis, Allison Loehr, Sudipta Mahajan, Zoya K. Arbiser, Jack L. Arbiser, Hiroki Onda, Erik J. Uhlmann, Hope Northrup, Xianhe Bai, Hailei Zhang
Publikováno v:
The American Journal of Pathology. 159:483-491
Angiomyolipomas are benign tumors of the kidney derived from putative perivascular epithelioid cells, that may undergo differentiation into cells with features of melanocytes, smooth muscle, and fat. To gain further insight into angiomyolipomas, we h
Autor:
Allison Loehr, Luba Roncari, Patrick Shannon, David H. Gutmann, Abhijit Guha, Nelson Lau, Matthias M. Feldkamp
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 59:759-767
Neurofibromatosis 1 (NF1) is a common autosomal dominant cancer predisposition syndrome, in which 15% to 20% of affected individuals develop astrocytomas. Neurofibromin, the protein product of the NF1 gene, functions as a tumor suppressor, largely by
Publikováno v:
Oncogene. 18(31)
Individuals affected with neurofibromatosis 1 (NF1) harbor increased numbers of GFAP-immunoreactive cerebral astrocytes and develop astrocytomas that can lead to blindness and death. Mice heterozygous for a targeted Nf1 mutation (Nf1+/-) were employe