Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Allison L. Arai"'
Autor:
Andrew E. Arai, Allison L. Arai
Publikováno v:
JACC: Cardiovascular Imaging.
Autor:
Dudley K. Strickland, David Peeney, William G. Stetler-Stevenson, Allison L. Arai, Selen C. Muratoglu, Mary Migliorini, Elizabeth Hahn-Dantona, Dianaly T. Au
Publikováno v:
Biochemistry
Matrix metalloprotease (MMP) activation contributes to the degradation of the extracellular matrix (ECM), resulting in a multitude of pathologies. Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifaceted endocytic and signaling rec
Autor:
Brajesh K. Lal, Jackie Zhang, Vicki L. Gray, Areck A. Ucuzian, Dudley K. Strickland, Brittany O. Aicher, Rebeca Galisteo, Selen C. Muratoglu, Allison L. Arai
Publikováno v:
Am J Physiol Heart Circ Physiol
Thoracic aortic aneurysm and dissection (TAAD) is a deadly disease characterized by intimal disruption induced by hemodynamic forces of the circulation. The effect of exercise in patients with TAAD is largely unknown. β-Aminopropionitrile (BAPN) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbf76766a400ed847d4f69faca86283
https://europepmc.org/articles/PMC8163659/
https://europepmc.org/articles/PMC8163659/
Autor:
Joanna M. Cooper, Bradley T. Hyman, Dudley K. Strickland, Selen C. Muratoglu, Allison L. Arai, Mary Migliorini
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Simon Dujardin, Dudley K. Strickland, Allison L. Arai, Molly Migliorini, Mashhood Wani, B. T. Hyman, Joanna M. Cooper, Aurélien Lathuilière, Selen C. Muratoglu
The identification of the apoE receptor, LRP1, as an endocytic receptor for tau raises several questions about LRP1s’ role in tauopathies. Is internalized tau, like other LRP1 ligands, delivered to lysosomes for degradation? Does LRP1 internalize p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dcf8436a7f69e8019c2890b7cfc4ff3
https://doi.org/10.1101/2020.11.17.386581
https://doi.org/10.1101/2020.11.17.386581
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30437 (2012)
P-element vectors are commonly used to make transgenic Drosophila and generally insert in the genome in a nonselective manner. However, when specific fragments of regulatory DNA from a few Drosophila genes are incorporated into P-transposons, they ca
Externí odkaz:
https://doaj.org/article/3fdc49d8bdb54bdf950b664a24466efa
Publikováno v:
Current Drug Targets. 19:1276-1288
Aortic aneurysms represent a significant clinical problem as they largely go undetected until a rupture occurs. Currently, an understanding of mechanisms leading to aneurysm formation is limited. Numerous studies clearly indicate that vascular smooth
Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke
Autor:
Afonso C. Silva, Cecil Chern-Chyi Yen, Byeong-Teck Kang, John M. Hallenbeck, Allison L. Arai, Yongshan Mou, Sang-Ho Choi
Publikováno v:
Stroke. 49:718-726
Background and Purpose— MAGL (monoacylglycerol lipase) is an enzyme that hydrolyzes the endocannabinoid 2-arachidonoylglycerol and regulates the production of arachidonic acid and prostaglandins—substances that mediate tissue inflammatory respons
Autor:
Mashhood Wani, Mary Migliorini, Dudley K. Strickland, Allison L. Arai, Bradley T. Hyman, Aurélien Lathuilière, Simon Dujardin, Selen C. Muratoglu, Joanna M. Cooper
Publikováno v:
Journal of Biological Chemistry
The Journal of Biological Chemistry
Journal of Biological Chemistry, Vol. 296 (2021) P. 100715
The Journal of Biological Chemistry
Journal of Biological Chemistry, Vol. 296 (2021) P. 100715
In Alzheimer's disease (AD), pathological forms of tau are transferred from cell to cell and "seed" aggregation of cytoplasmic tau. Phosphorylation of tau plays a key role in neurodegenerative tauopathies. In addition, apolipoprotein E (apoE), a majo
Autor:
Steven Warach, Erica C Henning, Renata F Leoni, Allison L Arai, Lawrence L Latour, Afonso C Silva
Publikováno v:
Stroke. 43
Introduction. Early blood-CSF barrier opening imaged as gadolinium enhancement of CSF on FLAIR MRI, the Hyperintense Acute Reperfusion Marker (HARM), has been associated with increased plasma MMP-9 in both clinical and experimental stroke [ 1 - 2 ].