Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Allison L Miller"'
Autor:
Leonie M. Hitchman, Allamanda Faatoese, Tony R. Merriman, Allison L. Miller, Yusmiati Liau, Oscar E. E. Graham, Ping Siu Kee, John F. Pearson, Tony Fakahau, Vicky A. Cameron, Martin A. Kennedy, Simran D. S. Maggo
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The enzyme cytochrome P450 2D6 (CYP2D6) metabolises approximately 25% of commonly prescribed drugs, including analgesics, anti-hypertensives, and anti-depressants, among many others. Genetic variation in drug metabolising genes can alter how an indiv
Externí odkaz:
https://doaj.org/article/31bf328d92e841b595815f8222e23b23
Autor:
Cynthia M. Bulik, Laura M. Thornton, Richard Parker, Hannah Kennedy, Jessica H. Baker, Casey MacDermod, Jerry Guintivano, Lana Cleland, Allison L. Miller, Lauren Harper, Janne T. Larsen, Zeynep Yilmaz, Jakob Grove, Patrick F. Sullivan, Liselotte V. Petersen, Jennifer Jordan, Martin A. Kennedy, Nicholas G. Martin
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The Eating Disorders Genetics Initiative (EDGI) is an international investigation exploring the role of genes and environment in anorexia nervosa, bulimia nervosa, and binge-eating disorder. Methods A total of 14,500 individuals w
Externí odkaz:
https://doaj.org/article/0e3bc23d32de45b7a0f64f8d0c26d4ac
Autor:
Ping Siu Kee, Simran D. S. Maggo, Martin A. Kennedy, Murray L. Barclay, Allison L. Miller, Klaus Lehnert, Maurice A. Curtis, Richard L. M. Faull, Remai Parker, Paul K. L. Chin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Omeprazole is extensively used to manage gastroesophageal reflux disease (GERD). It is primarily metabolized by CYP2C19. The CYP2C19*17 (rs12248560) allele and the recently described CYP2C:TG haplotype (rs11188059 and rs2860840) are associated with i
Externí odkaz:
https://doaj.org/article/1a6d85326f064630b4559320e165eea4
Autor:
Annika R. Seddon, Yusmiati Liau, Paul E. Pace, Allison L. Miller, Andrew B. Das, Martin A. Kennedy, Mark B. Hampton, Aaron J. Stevens
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background Environmental factors, such as oxidative stress, have the potential to modify the epigenetic landscape of cells. We have previously shown that DNA methyltransferase (DNMT) activity can be inhibited by sublethal doses of hydrogen p
Externí odkaz:
https://doaj.org/article/76705e9ea37444d39a7a32b5c3689805
Autor:
Simran Maggo, Martin A. Kennedy, Zoe A. Barczyk, Allison L. Miller, Julia J. Rucklidge, Roger T. Mulder, James A. Foulds
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Many patients prescribed an antidepressant stop taking it because of side effects. Genetic factors and psychological factors including state or trait anxiety, may explain variation in side effect outcomes. Our aim was to examine the relative contribu
Externí odkaz:
https://doaj.org/article/a19a26ddaa2040b39adb6212db005d15
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
We describe a case series of 22 individuals who were referred to our laboratory by a pharmacist based in a mental health hospital, for pharmacogenetic analysis due to severe or unexpected adverse drug reactions (ADRs) to psychiatric medication. The p
Externí odkaz:
https://doaj.org/article/835b0d1aaaf54e5ba1b4660b5b7cdad4
Autor:
Germán Pequeño, Stephen M. Coghlan, Ralph T. Lampman, Maria João Lança, Hiroaki Arakawa, Aleksandr Kucheryavyy, Allison L. Miller, C. S. Mateus, Cindy F. Baker, Seiji Yanai, Trent M. Sutton, Benjamin J. Clemens, Hassan Nazari
Publikováno v:
Journal of Great Lakes Research. 47:S129-S146
Ten anadromous lamprey species (Petromyzontiformes) are recognized around the world, including four species in the Southern Hemisphere and six in the Northern Hemisphere. Eleven threats to these anadromous lampreys have been identified: climate chang
Autor:
Martin A. Kennedy, Yusmiati Liau, Patrick Gladding, Simran Maggo, Allison L. Miller, Simone L. Cree, John F. Pearson
Publikováno v:
Pharmacogenetics and Genomics. 29:207-215
AimThe MinION nanopore sequencing device opens the opportunity to cost-effective and point-of-care DNA sequencing. We developed a multiplex assay targeting pharmacogenetic variants related to clopidogrel and warfarin, two commonly used drugs that sho
Autor:
Anna P. Pilbrow, Simon C. Body, Allison L. Miller, Sebastian Schmeier, Martin I. Sigurdsson, Vicky A. Cameron, Josh Gorham, Wendy E. Sweet, Jonathan G. Seidman, Jochen D. Muehlschlegel, John F. Pearson, Arthur Morley-Bunker, Louis A. Saddic, Christine S. Moravec, Sary F. Aranki, Zoe Ward
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11324, p 11324 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
Background: Long noncoding RNAs (lncRNAs) have been implicated in the pathogenesis of cardiovascular diseases. We aimed to identify novel lncRNAs associated with the early response to ischemia in the heart. Methods and Results: RNA sequencing data ga
Autor:
Bo Chen, Allison L Miller, Marlon Rebelatto, Yambasu Brewah, Daniel C Rowe, Lori Clarke, Meggan Czapiga, Kim Rosenthal, Tomozumi Imamichi, Yan Chen, Chew-Shun Chang, Partha S Chowdhury, Brian Naiman, Yue Wang, De Yang, Alison A Humbles, Ronald Herbst, Gary P Sims
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115828 (2015)
Release of endogenous damage associated molecular patterns (DAMPs), including members of the S100 family, are associated with infection, cellular stress, tissue damage and cancer. The extracellular functions of this family of calcium binding proteins
Externí odkaz:
https://doaj.org/article/60f3d5336bb947d188644086d880d193