Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Allison L Boyd"'
Autor:
Deanna P. Porras, Jennifer C. Reid, Borko Tanasijevic, Diana Golubeva, Allison L. Boyd, Mickie Bhatia
Publikováno v:
Cells, Vol 11, Iss 12, p 1915 (2022)
The generation of human hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) represents a major goal in regenerative medicine and is believed would follow principles of early development. HSCs arise from a type of endothelial cel
Externí odkaz:
https://doaj.org/article/19f4c3de54d34c008ebcff23688ec3d4
Autor:
Luca Orlando, Borko Tanasijevic, Mio Nakanishi, Jennifer C. Reid, Juan L. García-Rodríguez, Kapil Dev Chauhan, Deanna P. Porras, Lili Aslostovar, Justin D. Lu, Zoya Shapovalova, Ryan R. Mitchell, Allison L. Boyd, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108818- (2021)
Summary: Histone variants (HVs) are a subfamily of epigenetic regulators implicated in embryonic development, but their role in human stem cell fate remains unclear. Here, we reveal that the phosphorylation state of the HV H2A.X (γH2A.X) regulates s
Externí odkaz:
https://doaj.org/article/4557e53b20234f89a0c512ca3d13ed30
Autor:
Lili Aslostovar, Allison L. Boyd, Mohammed Almakadi, Tony J. Collins, Darryl P. Leong, Rommel G. Tirona, Richard B. Kim, Jim A. Julian, Anargyros Xenocostas, Brian Leber, Mark N. Levine, Ronan Foley, Mickie Bhatia
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1935-1945 (2018)
Abstract: We completed a phase 1 dose-escalation trial to evaluate the safety of a dopamine receptor D2 (DRD2) antagonist thioridazine (TDZ), in combination with cytarabine. Thirteen patients 55 years and older with relapsed or refractory acute myelo
Externí odkaz:
https://doaj.org/article/65462c7955b0444b8aa80b9a26bdee79
Autor:
Jennifer C. Reid, Borko Tanasijevic, Diana Golubeva, Allison L. Boyd, Deanna P. Porras, Tony J. Collins, Mickie Bhatia
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Summary: Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs ha
Externí odkaz:
https://doaj.org/article/ccabb1b5765542a4a5b34f9e544c110d
Autor:
Diana Golubeva, Deanna P Porras, Meaghan Doyle, Jennifer C Reid, Borko Tanasijevic, Allison L Boyd, Kinga Vojnits, Amro Elrafie, Amy Qiao, Mickie Bhatia
Publikováno v:
Stem Cells Translational Medicine.
Screening of primary patient acute myeloid leukemia (AML) cells is challenging based on intrinsic characteristics of human AML disease and patient-specific conditions required to sustain AML cells in culture. This is further complicated by inter- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42462bcbf8c7948f2d7cb845916aab1f
https://doi.org/10.1093/stcltm/szad022
https://doi.org/10.1093/stcltm/szad022
Perspective on This Article from Neonatal Experiences Differentially Influence Mammary Gland Morphology, Estrogen Receptor α Protein Levels, and Carcinogenesis in BALB/c Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f5e7c5167d9d0474c0a0d1356747e9
https://doi.org/10.1158/1940-6207.22524635.v1
https://doi.org/10.1158/1940-6207.22524635.v1
Supplementary Materials from Neonatal Experiences Differentially Influence Mammary Gland Morphology, Estrogen Receptor α Protein Levels, and Carcinogenesis in BALB/c Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672773500881f33d820ac0987b650f9c
https://doi.org/10.1158/1940-6207.22524632
https://doi.org/10.1158/1940-6207.22524632
Autor:
Antonino Neri, Fortunato Morabito, Jennifer C. Reid, Luca Orlando, Giovanna Cutrona, Andrew Leber, Mickie Bhatia, Massimo Gentile, Charisa Henly, Cameron G. Hollands, Josée Hébert, Diana Golubeva, Luca Agnelli, Brian Leber, Allison L. Boyd, Manlio Ferrarini
Publikováno v:
Cell reports. 34(11)
Identifying precise targets of individual cancers remains challenging. Chronic lymphocytic leukemia (CLL) represents the most common adult hematologic malignancy, and trisomy 12 (tri12) represents a quarter of CLL patients. We report that tri12 human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77c5874cf9c16d23c80369598322ba7
https://pubmed.ncbi.nlm.nih.gov/33730576
https://pubmed.ncbi.nlm.nih.gov/33730576
Autor:
Ronan Foley, Mickie Bhatia, Mark Levine, Darryl P. Leong, Brian Leber, Richard B. Kim, Mohammed Almakadi, Rommel G. Tirona, Anargyros Xenocostas, Jim A. Julian, Allison L. Boyd, Tony J. Collins, Lili Aslostovar
Publikováno v:
Paediatrics Publications
We completed a phase 1 dose-escalation trial to evaluate the safety of a dopamine receptor D2 (DRD2) antagonist thioridazine (TDZ), in combination with cytarabine. Thirteen patients 55 years and older with relapsed or refractory acute myeloid leukemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ff7b9ad8173ddf9b836387dcfa4ecb
https://doi.org/10.1182/bloodadvances.2018015677
https://doi.org/10.1182/bloodadvances.2018015677
Autor:
Mickie Bhatia, Allison L. Boyd, Jennifer C. Reid, Tony J. Collins, Deanna P. Porras, Borko Tanasijevic, Diana Golubeva
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Summary Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc539a3ba59823159b53dc7e37570e8
http://europepmc.org/articles/PMC5995456
http://europepmc.org/articles/PMC5995456