Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Allison K. Martin"'
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
CD4+ T cells drive the immunopathogenesis of chronic beryllium disease (CBD), and their recruitment to the lung heralds the onset of granulomatous inflammation. We have shown that CD4+ Tregs control granuloma formation in an HLA-DP2 Tg model of CBD.
Externí odkaz:
https://doaj.org/article/ccc2e836cc5f4fc9804c94a8f540850d
Autor:
Eric C. Logue, Allison K. Martin, C. Preston Neff, James C. Lavelle, Suzanne Fiorillo, Andrew P. Fontenot, Douglas G. Mack, R. William Vandivier, Thomas B. Campbell, Brent E. Palmer
Publikováno v:
The Journal of Immunology. 202:1363-1372
Recent studies suggest that HIV infection is an independent risk factor for the development of chronic obstructive pulmonary disease (COPD). We hypothesized that HIV infection and cigarette smoking synergize to alter the function of alveolar macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff5442e0eccb8708bcd37eb71cbaf6b
https://doi.org/10.4049/jimmunol.1801105
https://doi.org/10.4049/jimmunol.1801105
Autor:
Alex N. Tinega, Allison K. Martin, John W. Kappler, Douglas G. Mack, Lisa A. Maier, Michael T. Falta, Clemencia Pinilla, Frances Crawford, Jeremy Chase Crawford, Li Li, Paul G. Thomas, Shaikh M. Atif, Radleigh Santos, Laurie G. Landry, Maki Nakayama, Andrew P. Fontenot
Publikováno v:
J Clin Invest
Discovering dominant epitopes for T cells, particularly CD4+ T cells, in human immune-mediated diseases remains a significant challenge. Here, we used bronchoalveolar lavage (BAL) cells from HLA-DP2-expressing patients with chronic beryllium disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfdd75031b04936ec9af30746ce26ea
https://pubmed.ncbi.nlm.nih.gov/33938450
https://pubmed.ncbi.nlm.nih.gov/33938450
Autor:
Allison K. Martin, Charles A. Dinarello, Morgan K. Collins, Amy S. McKee, Andrew P. Fontenot, Denay J.K. Richards, Morgan F. Wade, Douglas G. Mack
Publikováno v:
The Journal of Immunology. 201:2232-2243
Metal-induced hypersensitivity is driven by dendritic cells (DCs) that migrate from the site of exposure to the lymph nodes, upregulate costimulatory molecules, and initiate metal-specific CD4+ T cell responses. Chronic beryllium disease (CBD), a lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cab3baebb0d347505251516f91c318
https://doi.org/10.4049/jimmunol.1800303
https://doi.org/10.4049/jimmunol.1800303
Autor:
Javier Rangel-Moreno, Rubin M. Tuder, Lisa A. Maier, Andrew P. Fontenot, Amy S. McKee, Allison K. Martin, Shaikh M. Atif, Douglas G. Mack, Andrew Getahun, John C. Cambier
Publikováno v:
JCI Insight. 4
Susceptibility to chronic beryllium (Be) disease (CBD) is linked to HLA-DP molecules possessing a glutamic acid at the 69th position of the β-chain (βGlu69), with the most prevalent βGlu69-containing molecule being HLA-DP2. We have previously show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e3bf8059de0256c38153f2f5ded1ba
https://doi.org/10.1172/jci.insight.125494
https://doi.org/10.1172/jci.insight.125494
Autor:
Claudia Chalk, Michael T. Aubrey, Andrew P. Fontenot, Allison K. Martin, Marchele Nowell-Bostic, Bruce C. Trapnell, Kirsten M. Anderson, Christina L. Roark, Brenna Carey, Brian M. Freed
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213179 (2019)
PLoS ONE
PLoS ONE
Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by the accumulation of pulmonary surfactant in alveolar macrophages and alveoli, resulting in respiratory impairment and an increased risk of opportunistic infections. Autoimmu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9563ccf80e5509368b22211fdb9b4a
https://doaj.org/article/87ed814ea9de47d2bf0509a8c337b269
https://doaj.org/article/87ed814ea9de47d2bf0509a8c337b269
Autor:
Sonia C. Flores, Andrew P. Fontenot, Thomas B. Campbell, Allison K. Martin, Brent E. Palmer, C. Preston Neff, Samantha MaWhinney, Derek J. Linderman, Jennifer L. Chain
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:464-473
Lymphocytic alveolitis in HIV-1-infected individuals is associated with multiple pulmonary complications and a poor prognosis. Although lymphocytic alveolitis has been associated with viremia and an increased number of CD8(+) T cells in the lung, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c83d6d0ea87b6200470a4d9b0f4d3c
https://doi.org/10.1164/rccm.201408-1521oc
https://doi.org/10.1164/rccm.201408-1521oc
Autor:
Frances Crawford, Douglas G. Mack, John W. Kappler, Terry Gordon, Allison K. Martin, Philip L. Simonian, Andrew P. Fontenot, Robert R. Mercer, Rubin M. Tuder, Amy S. McKee, Michael T. Falta, Mark D. Hoover, Philippa Marrack
Publikováno v:
Proceedings of the National Academy of Sciences. 111:8553-8558
Susceptibility to chronic beryllium disease (CBD) is linked to certain HLA-DP molecules, including HLA-DP2. To elucidate the molecular basis of this association, we exposed mice transgenic (Tg) for HLA-DP2 to beryllium oxide (BeO) via oropharyngeal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0351477d8ebf5691f3a0be2bd754a0ef
https://doi.org/10.1073/pnas.1408048111
https://doi.org/10.1073/pnas.1408048111
Autor:
Shaikh M Atif, Douglas Mack, Amy S McKee, Javier Rangel-Moreno, Allison K Martin, Andrew Getahun, Lisa A Maier, John C Cambier, Rubin M Tuder, Andrew P Fontenot
Publikováno v:
The Journal of Immunology. 202:182.68-182.68
Susceptibility to chronic beryllium disease (CBD)is linked to HLA-DP molecules possessing a glutamic acid at the 69thposition of the β-chain (βGlu69), with the most prevalent βGlu69-containing molecule being HLA-DP2. We have previously shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3fc5de663d251e7a30225eb31ef6de
https://doi.org/10.4049/jimmunol.202.supp.182.68
https://doi.org/10.4049/jimmunol.202.supp.182.68
Autor:
Allison K. Martin, Jennifer L. Chain, Douglas G. Mack, Andrew P. Fontenot, Lisa A. Maier, Brent E. Palmer
Publikováno v:
The Journal of Immunology. 191:1648-1656
Chronic beryllium disease (CBD) is an occupational lung disorder characterized by granulomatous inflammation and the accumulation of beryllium-responsive CD4+ T cells in the lung. These differentiated effector memory T cells secrete IL-2, IFN-γ, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4437de823f5d5f58f3d5ee9fe79d927
https://doi.org/10.4049/jimmunol.1300282
https://doi.org/10.4049/jimmunol.1300282