Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Allison K. Guitor"'
Autor:
Allison K. Guitor, Efrah I. Yousuf, Amogelang R. Raphenya, Eileen K. Hutton, Katherine M. Morrison, Andrew G. McArthur, Gerard D. Wright, Jennifer C. Stearns
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Probiotic use in preterm infants can mitigate the impact of antibiotic exposure and reduce rates of certain illnesses; however, the benefit on the gut resistome, the collection of antibiotic resistance genes, requires further inve
Externí odkaz:
https://doaj.org/article/aa90c63dd09342948c00878ee8e8ab7e
Autor:
Min Xu, Wenliang Wang, Nicholas Waglechner, Elizabeth J. Culp, Allison K. Guitor, Gerard D. Wright
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Expansion of the chemical diversity of glycopeptide antibiotics (GPAs) to deal with the emergence and spread of GPA resistance is challenging. Here, the authors report a GPA synthetic biology platform in Streptomyces coelicolor for Type IV–V glycop
Externí odkaz:
https://doaj.org/article/ab52388badb54b27817cdc937f1fa5d5
Autor:
Min Xu, Wenliang Wang, Nicholas Waglechner, Elizabeth J. Culp, Allison K. Guitor, Gerard D. Wright
Publikováno v:
ACS Central Science. 8:615-626
The rise and dissemination of glycopeptide antibiotic (GPA)-resistant pathogens in healthcare settings fuel efforts to discover GPAs that can overcome resistance. Members of the type V subclass of GPAs can evade common GPA resistance mechanisms and o
Autor:
Elizabeth J. Culp, Gerard D. Wright, Min Xu, Allison K. Guitor, Nicholas Waglechner, Wenliang Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Glycopeptide antibiotics (GPAs) are essential for the treatment of severe infectious diseases caused by Gram-positive bacteria. The emergence and spread of GPA resistance have propelled the search for more effective GPAs. Given their structural compl
Autor:
Andreea A. Gheorghita, Francis Wolfram, Gregory B. Whitfield, Holly M. Jacobs, Roland Pfoh, Steven S.Y. Wong, Allison K. Guitor, Mara C. Goodyear, Alison M. Berezuk, Cezar M. Khursigara, Matthew R. Parsek, P. Lynne Howell
Publikováno v:
The Journal of biological chemistry. 298(2)
Pseudomonas aeruginosa is an opportunistic human pathogen and a leading cause of chronic infection in the lungs of individuals with cystic fibrosis. After colonization, P. aeruginosa often undergoes a phenotypic conversion to mucoidy, characterized b
Publikováno v:
ACS infectious diseases. 7(6)
Increasing multidrug resistance in Neisseria gonorrheae is a growing public health crisis. Resistance to the last line therapies, cephalosporins and azithromycin, are of particular concern, fueling the need to discover new treatments. Here, we identi
Autor:
Hendrik N. Poinar, Andrew G. McArthur, Michael G. Surette, Melanie Kuch, Allison K. Guitor, Jennifer Klunk, Brian Alcock, Amogelang R. Raphenya, Gerard D. Wright
Publikováno v:
Antimicrobial Agents and Chemotherapy
Identification of the nucleotide sequences encoding antibiotic resistance elements and determination of their association with antibiotic resistance are critical to improve surveillance and monitor trends in antibiotic resistance. Current methods to
Autor:
Gerard D. Wright, Allison K. Guitor
Publikováno v:
Chest. 154(5)
Since their introduction into health care and clinical practice in the early 20th century, antibiotics have revolutionized medicine. Alarmingly, these drugs are increasingly threatened by bacteria that have developed a broad diversity of resistance m