Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Allison J. Applegate"'
Autor:
Brent J. Smith Jr, Jennifer D. Hintzsche, Carol M. Amato, Aik-Choon Tan, Keith R. Wells, Allison J. Applegate, Rita T. Gonzalez, Jodie R. Barr, William A. Robinson
Publikováno v:
Marshall Journal of Medicine, Vol 3, Iss 2, Pp 65-73 (2017)
The RET proto-oncogene encodes a receptor tyrosine kinase that is activated by glial cell derived neutrotrophic factor (GDNF). Previous studies have found that a single nucleotide polymorphism (SNP), RETp (G691S), in the juxtamembrane domain enhances
Externí odkaz:
https://doaj.org/article/00d39a5994854d9fa187a0ea659f7133
Autor:
Pratik S. Multani, Danielle Murphy, William A. Robinson, Allison J. Applegate, Anh T. Le, Robert C. Doebele, Matthew J. Rioth, Aik Choon Tan, Theresa Medina, Edna Chow-Maneval, John J. Tentler, Judson Bemis, Jennifer D. Hintzsche, Yiqun G. Shellman, Todd M. Pitts, Keith Wells, Jason Christiansen, Jacqueline A. Turner, Carol M. Amato, Stacey M. Bagby, Kasey L. Couts, Rene Gonzalez
Publikováno v:
Molecular Cancer Therapeutics. 17:222-231
Oncogenic ALK fusions occur in several types of cancer and can be effectively treated with ALK inhibitors; however, ALK fusions and treatment response have not been characterized in malignant melanomas. Recently, a novel isoform of ALK (ALKATI) was r
Autor:
Josianna V. Schwan, Yuchun Luo, Nabanita Mukherjee, Yan Lu, Yiqun G. Shellman, Allison J. Applegate, Katie A. Partyka, Adam R. Almeida, Steven E. Robinson, David A. Norris, William A. Robinson, Madison A. Rogers, Mayumi Fujita, Carol M. Amato, K. Lambert
Publikováno v:
Oncotarget
Major limitations of current melanoma treatments are for instances of relapse and the lack of therapeutic options for BRAF wild-type patients who do not respond to immunotherapy. Many studies therefore focus on killing resistant subpopulations, such
Autor:
Carol M. Amato, Karl D. Lewis, Nicholas T. Gorden, Allison J. Applegate, Jennifer D. Hintzsche, John J. Tentler, Kelsey E. Wuensch, Joshua Wisell, Neil F. Box, Martin D. McCarter, Rene Gonzalez, Theresa Medina, Steven E. Robinson, Kasey L. Couts, Jihye Kim, William A. Robinson, Yiqun G. Shellman, Keith Wells, Aik Choon Tan
Publikováno v:
Melanoma Research
Mucosal melanomas are a rare subtype of melanoma, arising in mucosal tissues, which have a very poor prognosis due to the lack of effective targeted therapies. This study aimed to better understand the molecular landscape of these cancers and find po