Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Allison J Cowin"'
Autor:
Abiodun D Ogunniyi, Zlatko Kopecki, Elizabeth E Hickey, Manouchehr Khazandi, Emma Peel, Katherine Belov, Alexandra Boileau, Sanjay Garg, Henrietta Venter, Wei Yee Chan, Peter B Hill, Stephen W Page, Allison J Cowin, Darren J Trott
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200195 (2018)
There are very few articles in the literature describing continuous models of bacterial infections that mimic disease pathogenesis in humans and animals without using separate cohorts of animals at each stage of disease. In this work, we developed bi
Externí odkaz:
https://doaj.org/article/4632a4228f75497d92cafa7122a9bfbe
Autor:
Clementine Menz, Mahroo K Parsi, Julian R J Adams, Mohamed A Sideek, Zlatko Kopecki, Allison J Cowin, Mark A Gibson
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135577 (2015)
Latent transforming growth factor-beta-1 binding protein-2 (LTBP-2) belongs to the fibrillin-LTBP superfamily of extracellular matrix proteins. LTBPs and fibrillins are involved in the sequestration and storage of latent growth factors, particularly
Externí odkaz:
https://doaj.org/article/8a3280fc95334851b02e0ab9e786e195
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123651 (2015)
Human keratinocytes are difficult to isolate and have a limited lifespan. Traditionally, immortalised keratinocyte cell lines are used in vitro due to their ability to bypass senescence and survive indefinitely. However these cells do not fully retai
Externí odkaz:
https://doaj.org/article/521d93d846ee4fa3824aebbc97d27fe1
Autor:
Veronika Bandara, Jade Foeng, Batjargal Gundsambuu, Todd S. Norton, Silvana Napoli, Dylan J. McPeake, Timona S. Tyllis, Elaheh Rohani-Rad, Caitlin Abbott, Stuart J. Mills, Lih Y. Tan, Emma J. Thompson, Vasiliki M. Willet, Victoria J. Nikitaras, Jieren Zheng, Iain Comerford, Adam Johnson, Justin Coombs, Martin K. Oehler, Carmela Ricciardelli, Allison J. Cowin, Claudine S. Bonder, Michael Jensen, Timothy J. Sadlon, Shaun R. McColl, Simon C. Barry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR)-T cell immunotherapy is a novel treatment that genetically modifies the patients’ own T cells to target and kill malignant cells. However, identification of tumour-specific antigens expressed on multiple sol
Externí odkaz:
https://doaj.org/article/a5287b5698b04be1aa66caa9922e1384
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(8)
Wound healing requires a complex cascade of highly controlled and conserved cellular and molecular processes. These involve numerous cell types and extracellular matrix molecules regulated by the actin cytoskeleton. This microscopic network of filame
Publikováno v:
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-10 (2020)
Abstract Healing of the skin and oral mucosa utilises similar mechanisms of tissue repair, however, scarring and the rate of wound closure is vastly superior in the oral cavity suggesting differences between these two environments. One key difference
Externí odkaz:
https://doaj.org/article/f9d3ec5e4f4d4552876c4600af3d1e58
Autor:
Aswathy Ravindran Girija, Xanthe Strudwick, Sivakumar Balasubramanian, Vivekanandan Palaninathan, Sakthikumar Dasappan Nair, Allison J. Cowin
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 880 (2023)
Background: Electrospun fibers are widely studied in regenerative medicine for their ability to mimic the extracellular matrix (ECM) and provide mechanical support. In vitro studies indicated that cell adhesion and migration is superior on smooth pol
Externí odkaz:
https://doaj.org/article/c75f7567921d488fab118cb3839132be
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/eebfcc7d329e4823b37f6dc12be7f6d7
Autor:
Parinaz Ahangar, Allison J. Cowin
Publikováno v:
Cells, Vol 11, Iss 18, p 2779 (2022)
The restoration of an intact epidermal barrier after wound injury is the culmination of a highly complex and exquisitely regulated physiological process involving multiple cells and tissues, overlapping dynamic events and protein synthesis and regula
Externí odkaz:
https://doaj.org/article/d1a5c04841144fd9b3f4e1a2d4eb2c75
Autor:
Alireza Hassanshahi, Mohammad Moradzad, Saman Ghalamkari, Moosa Fadaei, Allison J. Cowin, Mohammadhossein Hassanshahi
Publikováno v:
Cells, Vol 11, Iss 19, p 2953 (2022)
Macrophages are key immune cells that respond to infections, and modulate pathophysiological conditions such as wound healing. By possessing phagocytic activities and through the secretion of cytokines and growth factors, macrophages are pivotal orch
Externí odkaz:
https://doaj.org/article/28827c51d1a14b75bae3fb4ed829f611