Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Allison J Bardin"'
Autor:
Maheva Andriatsilavo, Marine Stefanutti, Katarzyna Siudeja, Carolina N Perdigoto, Benjamin Boumard, Louis Gervais, Alexandre Gillet-Markowska, Lara Al Zouabi, François Schweisguth, Allison J Bardin
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007773 (2018)
Precise regulation of stem cell self-renewal and differentiation properties is essential for tissue homeostasis. Using the adult Drosophila intestine to study molecular mechanisms controlling stem cell properties, we identify the gene split-ends (spe
Externí odkaz:
https://doaj.org/article/9428ca82e28e405e89d8c734572a0c90
Autor:
Mélanie Gracia, Bénédicte M. Lefèvre, Raquel Güell Alonso, Victoire Cachoux, Maria Balakireva, Boris Guirao, Damien Cuvelier, Allison J. Bardin, Yohanns Bellaïche
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102851- (2024)
Summary: Applying mechanical forces to tissues helps to understand morphogenesis and homeostasis. Additionally, recording the dynamics of living tissues under mechanical constraints is needed to explore tissue biomechanics. Here, we present a protoco
Externí odkaz:
https://doaj.org/article/1b218b5a0e8b4a8584235fea7dc36a11
Autor:
Lara Al Zouabi, Marine Stefanutti, Spyridon Roumeliotis, Gwenn Le Meur, Benjamin Boumard, Nick Riddiford, Natalia Rubanova, Mylène Bohec, Louis Gervais, Nicolas Servant, Allison J. Bardin
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113485- (2023)
Summary: During development and aging, genome mutation leading to loss of heterozygosity (LOH) can uncover recessive phenotypes within tissue compartments. This phenomenon occurs in normal human tissues and is prevalent in pathological genetic condit
Externí odkaz:
https://doaj.org/article/bc7cd3a3c8c7477faf2b30300a471dba
Autor:
Katarzyna Siudeja, Allison J. Bardin
Publikováno v:
Fly, Vol 11, Iss 2, Pp 121-128 (2017)
Somatic recombination is essential to protect genomes of somatic cells from DNA damage but it also has important clinical implications, as it is a driving force of tumorigenesis leading to inactivation of tumor suppressor genes. Despite this importan
Externí odkaz:
https://doaj.org/article/272c5e05560c49c89f76b21fd2d22bcc
Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells
Publikováno v:
Genome Res
Spontaneous mutations can alter tissue dynamics and lead to cancer initiation. While large-scale sequencing projects have illustrated processes that influence somatic mutation and subsequent tumour evolution, the mutational dynamics operating in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358b8f01f345fd643f34b8baf796c4db
https://doi.org/10.1101/gr.268441.120
https://doi.org/10.1101/gr.268441.120
Autor:
Alix Goupil, Jan Peter Heinen, Riham Salame, Fabrizio Rossi, Jose Reina, Carole Pennetier, Anthony Simon, Patricia Skorski, Anxela Louzao, Allison J. Bardin, Renata Basto, Cayetano Gonzalez
Publikováno v:
Development (Cambridge, England). 149(22)
While testing for genome instability in Drosophila as reported by unscheduled upregulation of UAS-GFP in cells that co-express GAL80 and GAL4, we noticed that, as expected, background levels were low in most developing tissues. However, GFP-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce013e94d674c5eb29fdb415deb40b6
https://pubmed.ncbi.nlm.nih.gov/36399062
https://pubmed.ncbi.nlm.nih.gov/36399062
Autor:
Allison J. Bardin, Benjamin Boumard
Publikováno v:
Current Opinion in Cell Biology
Current Opinion in Cell Biology, 2021, 73, pp.58-68. ⟨10.1016/j.ceb.2021.05.007⟩
Current Opinion in Cell Biology, Elsevier, 2021, 73, pp.58-68. ⟨10.1016/j.ceb.2021.05.007⟩
Current Opinion in Cell Biology, 2021, 73, pp.58-68. ⟨10.1016/j.ceb.2021.05.007⟩
Current Opinion in Cell Biology, Elsevier, 2021, 73, pp.58-68. ⟨10.1016/j.ceb.2021.05.007⟩
International audience; Stem cells have essential functions in the development and maintenance of our organs. Improper regulation of adult stem cells and tissue homeostasis can result in cancers and agedependent decline. Therefore, understanding how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1280cf88d13a2658a8d1dc6b6cfb5c
https://hal.science/hal-03442869
https://hal.science/hal-03442869
Autor:
van den Beek M, Wurmser A, Benjamin Boumard, Sonia Lameiras, Nick Riddiford, Katarzyna Siudeja, Allison J. Bardin, Marine Stefanutti
Transposable elements (TEs) play a significant role in evolution by contributing to genetic variation through germline insertional activity. However, how TEs act in somatic cells and tissues is not well understood. Here, we address the prevalence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdd1cde86ae5b7069184a44c93dbb17
https://hal.archives-ouvertes.fr/hal-03442848
https://hal.archives-ouvertes.fr/hal-03442848
Autor:
Benjamin Boumard, Allison J. Bardin
Publikováno v:
Current Opinion in Cell Biology. 76:102078
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a8104f1a8261490e2b117ee3ee5d27
https://doi.org/10.1016/j.ceb.2022.102078
https://doi.org/10.1016/j.ceb.2022.102078
Autor:
Louis, Gervais, Allison J, Bardin
Publikováno v:
Nat Cell Biol
The Drosophila trachea, as the functional equivalent of mammalian blood vessels, senses hypoxia and oxygenates the body. We show that the adult intestinal tracheae are dynamic and respond to enteric infection, oxidative agents, and tumors with increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3805c45c8b0e989583ec2d9bb631e1be
https://pubmed.ncbi.nlm.nih.gov/33972730
https://pubmed.ncbi.nlm.nih.gov/33972730