Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Allison J, Cowin"'
Autor:
Veronika Bandara, Jade Foeng, Batjargal Gundsambuu, Todd S. Norton, Silvana Napoli, Dylan J. McPeake, Timona S. Tyllis, Elaheh Rohani-Rad, Caitlin Abbott, Stuart J. Mills, Lih Y. Tan, Emma J. Thompson, Vasiliki M. Willet, Victoria J. Nikitaras, Jieren Zheng, Iain Comerford, Adam Johnson, Justin Coombs, Martin K. Oehler, Carmela Ricciardelli, Allison J. Cowin, Claudine S. Bonder, Michael Jensen, Timothy J. Sadlon, Shaun R. McColl, Simon C. Barry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR)-T cell immunotherapy is a novel treatment that genetically modifies the patients’ own T cells to target and kill malignant cells. However, identification of tumour-specific antigens expressed on multiple sol
Externí odkaz:
https://doaj.org/article/a5287b5698b04be1aa66caa9922e1384
Autor:
Tahlia L. Kennewell, Hanif Haidari, Suzanne Mashtoub, Gordon S. Howarth, Catherine Bennett, Clare M. Cooksley, Peter John Wormald, Allison J. Cowin, Sarah Vreugde, Zlatko Kopecki
Publikováno v:
Materials, Vol 17, Iss 4, p 793 (2024)
Pseudomonas aeruginosa is one of the most common pathogens encountered in clinical wound infections. Clinical studies have shown that P. aeruginosa infection results in a larger wound area, inhibiting healing, and a high prevalence of antimicrobial r
Externí odkaz:
https://doaj.org/article/c40e2dbdb2a04446a2dbfb9bf8cf4e7c
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(8)
Wound healing requires a complex cascade of highly controlled and conserved cellular and molecular processes. These involve numerous cell types and extracellular matrix molecules regulated by the actin cytoskeleton. This microscopic network of filame
Autor:
Aswathy Ravindran Girija, Xanthe Strudwick, Sivakumar Balasubramanian, Vivekanandan Palaninathan, Sakthikumar Dasappan Nair, Allison J. Cowin
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 880 (2023)
Background: Electrospun fibers are widely studied in regenerative medicine for their ability to mimic the extracellular matrix (ECM) and provide mechanical support. In vitro studies indicated that cell adhesion and migration is superior on smooth pol
Externí odkaz:
https://doaj.org/article/c75f7567921d488fab118cb3839132be
Publikováno v:
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-10 (2020)
Abstract Healing of the skin and oral mucosa utilises similar mechanisms of tissue repair, however, scarring and the rate of wound closure is vastly superior in the oral cavity suggesting differences between these two environments. One key difference
Externí odkaz:
https://doaj.org/article/f9d3ec5e4f4d4552876c4600af3d1e58
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Surgical repair of tendons is common, but function is often limited due to the formation of flexor tendon adhesions which reduce the mobility and use of the affected digit and hand. The severity of adhesion formation is dependent
Externí odkaz:
https://doaj.org/article/1bd42acf65aa45c5983b52d3ed74d363
Autor:
Parinaz Ahangar, Stuart J. Mills, Louise E. Smith, Xanthe L. Strudwick, Anthony E. Ting, Bart Vaes, Allison J. Cowin
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Stem cell therapies have been widely investigated for their healing effects. However, the translation of these therapies has been hampered by the requirement to deliver live allogeneic or autologous cells directly to the wound in
Externí odkaz:
https://doaj.org/article/ea3486e4d824405bbf0ed521f92e64a6
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Healing of tendons after injury involves the proliferation of tenocytes and the production of extracellular matrix; however, their capacity to heal is limited by poor cell density and limited growth factor activity. Flightless I (
Externí odkaz:
https://doaj.org/article/564e55e2f15f4eb69f4022bb07c9462b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 797 (2023)
Fundamental knowledge about cell–surface interactions can be applied in the development of wound dressings and scaffolds to encourage wounds to heal. As surfaces produced with acid-functionalised monomers encourage keratinocyte adhesion, proliferat
Externí odkaz:
https://doaj.org/article/f8e99cfb2bcf4bf48ef69c6897dacbbb
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/eebfcc7d329e4823b37f6dc12be7f6d7