Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Allison G, Condie"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0131330 (2015)
DNA damage and repair is a fundamental process that plays an important role in cancer treatment. Base excision repair (BER) is a major repair pathway that often leads to drug resistance in DNA-targeted cancer chemotherapy. In order to measure BER, we
Externí odkaz:
https://doaj.org/article/b5b2733afa784dd693cca428b5e410e6
Autor:
Shriya Srinivasan, Allison G. Condie, Stanton L. Gerson, Yanming Wang, Rajesh Seenivasan, Clemens Burda
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 3, p 471 (2019)
Volume 20
Issue 3
International Journal of Molecular Sciences, Vol 20, Iss 3, p 471 (2019)
Volume 20
Issue 3
Chemotherapeutic dosing, is largely based on the tolerance levels of toxicity today. Molecular imaging strategies can be leveraged to quantify DNA cytotoxicity and thereby serve as a theranostic tool to improve the efficacy of treatments. Methoxyamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7087814e2ee056d1a214b0921d4ca336
https://pubmed.ncbi.nlm.nih.gov/30678294
https://pubmed.ncbi.nlm.nih.gov/30678294
Autor:
Shuming Yang, Allison G. Condie, Xiangzi Han, Yan Xu, Yulan Qing, Yan Yan, Stanton L. Gerson, Shashank Gorityala, Youwei Zhang
Publikováno v:
Oncotarget
// Yan Yan 1 , Xiangzi Han 1 , Yulan Qing 2 , Allison G. Condie 3 , Shashank Gorityala 4 , Shuming Yang 2 , Yan Xu 2, 4 , Youwei Zhang 1 , Stanton L. Gerson 2 1 Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA 2 Departm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32568783a8934112a8850ce8391f2021
https://doi.org/10.18632/oncotarget.11151
https://doi.org/10.18632/oncotarget.11151
Autor:
Changning Wang, Christopher A Flask, Robert H. Miller, Chunying Wu, Junqing Zhu, Eduardo Somoza, Wenxia Zhu, Allison G. Condie, Daniela C. Popescu, Wendy B. Macklin, Yanming Wang
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:8592-8599
C-11-labeled N-methyl-4,4'-diaminostilbene ([(11)C]MeDAS) was synthesized and evaluated as a novel radiotracer for in vivo microPET imaging of myelination. [(11)C]MeDAS exhibits optimal lipophilicity for brain uptake with a logP(oct) value of 2.25. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0364d427e176320cfaa4b08e58c7c475
https://doi.org/10.1016/j.bmc.2010.10.018
https://doi.org/10.1016/j.bmc.2010.10.018
Publikováno v:
The Journal of Organic Chemistry. 74:2527-2532
A new class of polycalix[4]arene hosts has been constructed based on a carbosilane dendrimer architecture, in which each dendritic branch terminates with a calix[4]arene entity. This study reports the synthesis and characterization of the zeroth gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c96762482eda70640d2406195c6f18
https://doi.org/10.1021/jo802714q
https://doi.org/10.1021/jo802714q
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0131330 (2015)
PLoS ONE, Vol 10, Iss 8, p e0131330 (2015)
DNA damage and repair is a fundamental process that plays an important role in cancer treatment. Base excision repair (BER) is a major repair pathway that often leads to drug resistance in DNA-targeted cancer chemotherapy. In order to measure BER, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0163e7b3072f1bfc6d78219061559d99
https://pubmed.ncbi.nlm.nih.gov/26309022
https://pubmed.ncbi.nlm.nih.gov/26309022
Publikováno v:
ChemMedChem. 7(12)
Myelination is a fundamental biological process in the vertebrate nervous system. Damage to or malformation of myelin can lead to various neurological diseases; for example, demyelination in the spinal cord is a major cause of paralysis of patients s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfe623d10ef3bb9eb3fb7e0e2589748
https://pubmed.ncbi.nlm.nih.gov/23136014
https://pubmed.ncbi.nlm.nih.gov/23136014
Autor:
Bryan S, Matsuura, Allison G, Condie, Ian A, McBee, Ryan C, Buff, Gregory J, Karahalis, Corey R J, Stephenson
Publikováno v:
Organic letters. 13(23)
An intramolecular cyclization cascade reaction has been developed utilizing a high valent palladium intermediate that generates a carbon-carbon and carbon-oxygen bond in a single transformation. This method provides rapid access to highly functionali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0318f7986f691ce252d349e4b394845
https://pubmed.ncbi.nlm.nih.gov/22070096
https://pubmed.ncbi.nlm.nih.gov/22070096
Publikováno v:
ChemInform. 41
We report the application of visible-light photoredox catalysis for the formation of C−C bonds between tertiary N-arylamines and nitroalkanes via an oxidative aza-Henry reaction. In the presence of 1 mol % Ir(ppy)2(dtbbpy)PF6, efficient coupling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a650fed2819250990dab848b3227976f
https://doi.org/10.1002/chin.201029167
https://doi.org/10.1002/chin.201029167
Publikováno v:
Journal of the American Chemical Society. 132(5)
We report the application of visible-light photoredox catalysis for the formation of C-C bonds between tertiary N-arylamines and nitroalkanes via an oxidative aza-Henry reaction. In the presence of 1 mol % Ir(ppy)(2)(dtbbpy)PF(6), efficient coupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65463adb5983964a08a8378287482e08
https://pubmed.ncbi.nlm.nih.gov/20070079
https://pubmed.ncbi.nlm.nih.gov/20070079