Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Allison E, Norlander"'
Autor:
Ela W. Contreras-Panta, Su-Hyung Lee, Yoonkyung Won, Allison E. Norlander, Alan J. Simmons, R. Stokes Peebles, Jr., Ken S. Lau, Eunyoung Choi, James R. Goldenring
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 3, Pp 101366- (2024)
Background & Aims: Type 2 innate lymphoid cells (ILC2s) and interleukin-13 (IL-13) promote the onset of spasmolytic polypeptide-expressing metaplasia (SPEM) cells. However, little is known about molecular effects of IL-13 in SPEM cells. We now sought
Externí odkaz:
https://doaj.org/article/3f940af3bdcd40e5b822af7b7b0a90b6
Autor:
Vivek D. Gandhi, Jacqueline-Yvonne Cephus, Allison E. Norlander, Nowrin U. Chowdhury, Jian Zhang, Zachary J. Ceneviva, Elie Tannous, Vasiliy V. Polosukhin, Nathan D. Putz, Nancy Wickersham, Amrit Singh, Lorraine B. Ware, Julie A. Bastarache, Ciara M. Shaver, Hong Wei Chu, R. Stokes Peebles Jr., Dawn C. Newcomb
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 4 (2022)
Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and IL-13 production and eosinophil infiltration. Foxp3+ Tregs suppress an
Externí odkaz:
https://doaj.org/article/61b7abbe00a848c7a388570da40f9c5b
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 606-616 (2016)
Inflammatory cytokines play a major role in the pathophysiology of hypertension. The authors previously showed that genetic deletion of interleukin (IL)-17A results in blunted hypertension and reduced renal/vascular dysfunction. With the emergence of
Externí odkaz:
https://doaj.org/article/be475722346349c18ade279e5f13cb6e
Cystic Fibrosis Reprograms Airway Epithelial IL-33 Release and Licenses IL-33 Dependent Inflammation
Autor:
Daniel P. Cook, Christopher M Thomas, Ashley Y Wu, Mark Rusznak, Jian Zhang, Weisong Zhou, Jacqueline-Yvonne Cephus, Katherine N Gibson-Corley, Vasiliy V Polosukhin, Allison E Norlander, Dawn C Newcomb, David A Stoltz, R. Stokes Peebles
Publikováno v:
American Journal of Respiratory and Critical Care Medicine.
Publikováno v:
Viruses, Vol 12, Iss 5, p 521 (2020)
Respiratory syncytial virus (RSV) is a common and contagious virus that results in acute respiratory tract infections in infants. In many cases, the symptoms of RSV remain mild, however, a subset of individuals develop severe RSV-associated bronchiol
Externí odkaz:
https://doaj.org/article/cf373f5aab084a78b4e4df833c793a7d
Publikováno v:
DNA and Cell Biology. 40:1231-1234
T regulatory cells (Tregs) are an important member of the adaptive immune system and function to reduce and resolve inflammation. Prostaglandin I2 (PGI2) is a lipid mediator that has potent anti-in...
Autor:
Tianxiao Huan, Qingying Meng, Mohamed A Saleh, Allison E Norlander, Roby Joehanes, Jun Zhu, Brian H Chen, Bin Zhang, Andrew D Johnson, Saixia Ying, Paul Courchesne, Nalini Raghavachari, Richard Wang, Poching Liu, The International Consortium for Blood Pressure GWAS (ICBP), Christopher J O'Donnell, Ramachandran Vasan, Peter J Munson, Meena S Madhur, David G Harrison, Xia Yang, Daniel Levy
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 4, Pp 1-15 (2015)
Abstract Genome‐wide association studies (GWAS) have identified numerous loci associated with blood pressure (BP). The molecular mechanisms underlying BP regulation, however, remain unclear. We investigated BP‐associated molecular mechanisms by i
Externí odkaz:
https://doaj.org/article/fc9baddf1ae04a2bb009fde78b416935
Publikováno v:
Hypertension. 79
In recent years, inflammation was determined to play a causal role in hypertension. Interestingly, evidence suggests that long-lasting use of cyclooxygenase inhibitors, which prevent metabolism of arachidonic acid (AA) to prostaglandins and thromboxa
Autor:
Kelli L. Boyd, Kasia Goleniewska, Weisong Zhou, Shinji Toki, Dawn C. Newcomb, Pingsheng Wu, Hirohito Kita, R. Stokes Peebles, Jian Zhang, Allison E. Norlander
Publikováno v:
The Journal of Immunology. 205:1157-1166
The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens, such as Alternaria alternata, is not fully defined
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623633
Methods Mol Biol
Methods Mol Biol
Respiratory syncytial virus (RSV) infection causes considerable mortality and morbidity in infants and young children. RSV infection appears to elicit a mixed immune response characterized by both Th1-type cells and Th2-type cells. This immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c665a91d9dad669110e0bdbbc6c13e
https://doi.org/10.1007/978-1-0716-2364-0_2
https://doi.org/10.1007/978-1-0716-2364-0_2