Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Allison C. Bain"'
Publikováno v:
Journal of Neurotrauma. 18:499-511
In this investigation, the relationships between stretch and both morphological and electrophysiological signs of axonal injury were examined in the guinea pig optic nerve stretch model. Additionally, the relationship between axonal morphology and el
Autor:
Tracy K. McIntosh, Douglas T. Ross, Thomas A. Gennarelli, Douglas H. Smith, David I. Shreiber, David F. Meaney, Allison C. Bain
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 58:153-164
We used a new approach, termed dynamic cortical deformation (DCD), to study the neuronal, vascular, and glial responses that occur in focal cerebral contusions. DCD produces experimental contusion by rapidly deforming the cerebral cortex with a trans
Autor:
W. T. Adamson, Robert J. Smith, W. Zhang, Mark P. Mantell, Allison C. Bain, Wayne N. Frankel, T. R. Ziegler, J. C. Chow, Jonathan A. Roth, John L. Rombeau
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 269:G974-G980
The effects of exogenous insulin-like growth factor-I (IGF-I) on colonic adaptation were examined in male Sprague-Dawley rats (n = 60, 225-275 mg) after either a 60% small bowel and cecal resection (RX) or mid-small bowel transection with reanastomos
Publikováno v:
Journal of biomechanical engineering. 125(6)
Damage to axons and glial cells in the central nervous system (CNS) white matter is a nearly universal feature of traumatic brain injury, yet it is not clear how the tissue mechanical deformations are transferred to the cellular components of the CNS
Autor:
David F. Meaney, Allison C. Bain
Publikováno v:
Journal of biomechanical engineering. 122(6)
In vivo, tissue-level, mechanical thresholds for axonal injury were determined by comparing morphological injury and electrophysiological impairment to estimated tissue strain in an in vivo model of axonal injury. Axonal injury was produced by dynami
Publikováno v:
Advances in Bioengineering.
A prosthetic disc nucleus device has been designed to replace the degenerated lumbar intervertebral disc (IVD) nucleus. In this study, we measured the creep response of a lumbar motion segment in the intact condition, after a nucleotomy, and after im
Autor:
David F. Meaney, Allison C. Bain
Publikováno v:
SAE Technical Paper Series.
In vivo, tissue-level, mechanical thresholds for axonal injury in the guinea pig optic nerve were determined by comparing morphological injury to estimated in vivo tissue strain. The right optic nerve of adult male guinea pigs was stretched to one of
Autor:
Allison C. Bain, David F. Meaney
Publikováno v:
Advances in Bioengineering.
Diffuse axonal injury (DAI) is the most common form of closed head injury and is responsible for over a third of all head injury deaths. Axons are the primary constituent of the white matter in the brain, and frequently form aligned tracts in the bra
Autor:
David F. Meaney, David I. Shreiber, Allison C. Bain, Reid T. Miller, Douglas H. Smith, Doug T. Ross, Thomas A. Gennarelli
Publikováno v:
Journal of neurotrauma. 12(4)
The purpose of this paper is to present results from methodologies used in our laboratory that are targeted toward identifying specific brain injury thresholds. Results from studying one form of brain injury, diffuse axonal injury, are presented in t
Publikováno v:
The Journal of surgical research. 59(1)
IGF-I, a mitogenic polypeptide hormone, and glutamine (GLN), the preferred enterocyte fuel, singularly improve growth and structure of the small bowel isograft; however, their combined effects on intestinal allografts are unknown. This study examined