Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Allison C, Nugent"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The hippocampus and amygdala have been implicated in the pathophysiology and treatment of major depressive disorder (MDD). Preclinical models suggest that stress-related changes in these regions can be reversed by antidepressants, including
Externí odkaz:
https://doaj.org/article/b73ac47a61bd4a40983543de395d3517
Autor:
Allison C. Nugent, Adam G. Thomas, Margaret Mahoney, Alison Gibbons, Jarrod T. Smith, Antoinette J. Charles, Jacob S. Shaw, Jeffrey D. Stout, Anna M. Namyst, Arshitha Basavaraj, Eric Earl, Travis Riddle, Joseph Snow, Shruti Japee, Adriana J. Pavletic, Stephen Sinclair, Vinai Roopchansingh, Peter A. Bandettini, Joyce Chung
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Measurement(s) brain activity • Blood Oxygen Level-Dependent Functional MRI • regional part of brain • cerebral white matter structure • cerebral blood flow Technology Type(s) Magnetoencephalography • Functional Magnetic Resonance Imaging
Externí odkaz:
https://doaj.org/article/ae9bc5ce06d4469faf9474eb06d62b76
Publikováno v:
Neuroimage: Reports, Vol 2, Iss 2, Pp 100093- (2022)
Currently, the gold standard for high-resolution mapping of cortical electrophysiological activity is invasive electrocorticography (ECoG), a procedure that carries with it the risk of serious morbidity and mortality. Due to these risks, the use of E
Externí odkaz:
https://doaj.org/article/ac2aced164c04fd0ab6840c11b01c05d
Publikováno v:
Neuroimage: Reports, Vol 1, Iss 3, Pp 100034- (2021)
The basal ganglia are a crucial component of neural networks underlying reward response and many other behaviors. Magnetoencephalography (MEG) can be used to non-invasively study the spatiotemporal dynamics of activity in neural networks. However, ch
Externí odkaz:
https://doaj.org/article/6140962ee16c49dfa85fd5597796be5a
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The glutamatergic modulator ketamine rapidly reduces depressive symptoms in individuals with treatment-resistant major depressive disorder (TRD) and bipolar disorder. While its underlying mechanism of antidepressant action is not fully understood, mo
Externí odkaz:
https://doaj.org/article/7fd18da8aa5147b88e7cdef797eaefd7
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Despite decades of research, the rate of death from suicide is rising in the United States. Suicide is a complex and multifactorial phenomenon and, to date, no validated biomarkers that predict suicidal behavior have been identifi
Externí odkaz:
https://doaj.org/article/26da532345c144b28af233ce0d3ca8c7
Autor:
Elizabeth D. Ballard, Jessica R. Gilbert, Jessica S. Fields, Allison C. Nugent, Carlos A. Zarate
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Limited knowledge exists regarding the neurobiology of suicidal thoughts, given that there are currently no direct probes of the suicidal state. This pilot study used magnetoencephalography (MEG) to evaluate correlates of the implicit association bet
Externí odkaz:
https://doaj.org/article/c31732c3c98d47f782bde56539ff5f97
Autor:
Allison C. Nugent, Elizabeth D. Ballard, Jessica R. Gilbert, Prejaas K. Tewarie, Matthew J. Brookes, Carlos A. Zarate
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Major depressive disorder (MDD) is highly prevalent and frequently disabling. Only about 30% of patients respond to a first-line antidepressant treatment, and around 30% of patients are classified as “treatment-resistant” after failing to respond
Externí odkaz:
https://doaj.org/article/eae17fea17064317b355d28a4e3da8f0
Autor:
Allison C. Nugent, Elizabeth D. Ballard, Jessica R. Gilbert, Prejaas K. Tewarie, Matthew J. Brookes, Carlos A. Zarate, Jr.
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102378- (2020)
Major depressive disorder (MDD) is highly heterogeneous in its clinical presentation. The present exploratory study used magnetoencephalography (MEG) to investigate electrophysiological intrinsic connectivity differences between healthy volunteers an
Externí odkaz:
https://doaj.org/article/45a3f88203054f8bbdc1cb9318f8986b
Autor:
Jessica L. Reed, Allison C. Nugent, Maura L. Furey, Joanna E. Szczepanik, Jennifer W. Evans, Carlos A. Zarate, Jr
Publikováno v:
NeuroImage: Clinical, Vol 20, Iss , Pp 92-101 (2018)
Background: An urgent need exists for faster-acting pharmacological treatments in major depressive disorder (MDD). The glutamatergic modulator ketamine has been shown to have rapid antidepressant effects, but much remains unknown about its mechanism
Externí odkaz:
https://doaj.org/article/d71702292d144db98c770558ff0162be