Human neocortical expansion involves glutamatergic neuron diversification

Autor: Tim S. Heistek, Thomas Braun, Natalia A. Goriounova, Michael Tieu, Lindsay Ng, Michael Hawrylycz, Kris Bickley, Anton Arkhipov, Colin Farrell, Trangthanh Pham, Alexandra Glandon, Daniel Park, Gábor Molnár, Herman Tung, Allan R. Jones, Lisa Keene, Gáspár Oláh, Thomas Chartrand, Amy Torkelson, Jae Geun Yoon, Rachel A. Dalley, Aaron Szafer, Nick Dee, Brian E. Kalmbach, Eliza Barkan, Allison Beller, Krissy Brouner, Andrew L. Ko, Alex M. Henry, Viktor Szemenyei, Julie Nyhus, Staci A. Sorensen, Samuel Dingman Lee, Norbert Mihut, Amy Bernard, Lisa Kim, Anatoly Buchin, Melissa Gorham, Lucas T. Graybuck, Lydia Potekhina, Katelyn Ward, Caitlin S. Latimer, Aaron Oldre, Gabe J. Murphy, Boaz P. Levi, Trygve E. Bakken, René Wilbers, Jonathan T. Ting, Kimberly A. Smith, Amanda Gary, Songlin Ding, Alice Mukora, Matthew Kroll, Anoop P. Patel, Wayne Wakeman, Hongkui Zeng, Nadezhda Dotson, Rusty Mann, Victoria Omstead, Leona Mezei, Desiree A. Marshall, Shea Ransford, Lydia Ng, Sara Kebede, Gábor Tamás, Jeffrey G. Ojemann, Stephanie Mok, Nathan Hansen, Christina A. Pom, Brian Lee, Jim Berg, Ramkumar Rajanbabu, John W. Phillips, Philip R. Nicovich, Matthew Mallory, Richard G. Ellenbogen, Rachel Enstrom, Luke Esposito, Tim Jarsky, Di Jon Hill, Idan Segev, Darren Bertagnolli, Agata Budzillo, Sander Idema, Daniel L. Silbergeld, Costas A. Anastassiou, Chris Hill, Michelle Maxwell, Mean Hwan Kim, Charles Cobbs, Delissa McMillen, Bosiljka Tasic, Olivia Fong, Medea McGraw, Hong Gu, Kirsten Crichton, David Reid, Kristen Hadley, Lauren Alfiler, Manuel Ferreira, Elliot R. Thomsen, Kiet Ngo, Josef Sulc, Augustin Ruiz, Katherine Baker, Zizhen Yao, Erica J. Melief, Femke Waleboer, Hanchuan Peng, Grace Williams, Rebecca D. Hodge, Kyla Berry, Katherine E. Link, David Sandman, Tsega Desta, Christine Rimorin, Jeff Goldy, Ryder P. Gwinn, Djai B. Heyer, Changkyu Lee, Jeremy A. Miller, Nathan W. Gouwens, Pál Barzó, Attila Ozsvár, Huibert D. Mansvelder, Sergey L. Gratiy, Rafael Yuste, David Feng, Jessica Trinh, Clare Gamlin, Tamara Casper, C. Dirk Keene, Susan M. Sunkin, Tom Egdorf, Philip C. De Witt Hamer, Rebecca de Frates, Peter Chong, Szabina Furdan, Patrick R. Hof, Jasmine Bomben, Christiaan P. J. de Kock, Eline J. Mertens, Ed S. Lein, Anna A. Galakhova, Florence D’Orazi, Christof Koch, Madie Hupp

Publikováno v: Berg, J, Sorensen, S A, Ting, J T, Miller, J A, Chartrand, T, Buchin, A, Bakken, T E, Budzillo, A, Dee, N, Ding, S L, Gouwens, N W, Hodge, R D, Kalmbach, B, Lee, C, Lee, B R, Alfiler, L, Baker, K, Barkan, E, Beller, A, Berry, K, Bertagnolli, D, Bickley, K, Bomben, J, Braun, T, Brouner, K, Casper, T, Chong, P, Crichton, K, Dalley, R, de Frates, R, Desta, T, Lee, S D, D’Orazi, F, Dotson, N, Egdorf, T, Enstrom, R, Farrell, C, Feng, D, Fong, O, Furdan, S, Galakhova, A A, Gamlin, C, Gary, A, Glandon, A, Goldy, J, Gorham, M, Goriounova, N A, Gratiy, S, Graybuck, L, Gu, H, Hadley, K, Hansen, N, Heistek, T S, Henry, A M, Heyer, D B, Hill, D J, Hill, C, Hupp, M, Jarsky, T, Kebede, S, Keene, L, Kim, L, Kim, M H, Kroll, M, Latimer, C, Levi, B P, Link, K E, Mallory, M, Mann, R, Marshall, D, Maxwell, M, McGraw, M, McMillen, D, Melief, E, Mertens, E J, Mezei, L, Mihut, N, Mok, S, Molnar, G, Mukora, A, Ng, L, Ngo, K, Nicovich, P R, Nyhus, J, Olah, G, Oldre, A, Omstead, V, Ozsvar, A, Park, D, Peng, H, Pham, T, Pom, C A, Potekhina, L, Rajanbabu, R, Ransford, S, Reid, D, Rimorin, C, Ruiz, A, Sandman, D, Sulc, J, Sunkin, S M, Szafer, A, Szemenyei, V, Thomsen, E R, Tieu, M, Torkelson, A, Trinh, J, Tung, H, Wakeman, W, Waleboer, F, Ward, K, Wilbers, R, Williams, G, Yao, Z, Yoon, J G, Anastassiou, C, Arkhipov, A, Barzo, P, Bernard, A, Cobbs, C, de Witt Hamer, P C, Ellenbogen, R G, Esposito, L, Ferreira, M, Gwinn, R P, Hawrylycz, M J, Hof, P R, Idema, S, Jones, A R, Keene, C D, Ko, A L, Murphy, G J, Ng, L, Ojemann, J G, Patel, A P, Phillips, J W, Silbergeld, D L, Smith, K, Tasic, B, Yuste, R, Segev, I, de Kock, C P J, Mansvelder, H D, Tamas, G, Zeng, H, Koch, C & Lein, E S 2021, ' Human neocortical expansion involves glutamatergic neuron diversification ', Nature, vol. 598, no. 7879, pp. 151-158 . https://doi.org/10.1038/s41586-021-03813-8
Nature, 598(7879), 151-158. Nature Publishing Group
Nature
Nature, Vol. 598, No. 7879
Berg, J, Sorensen, S A, Ting, J T, Miller, J A, Chartrand, T, Buchin, A, Bakken, T E, Budzillo, A, Dee, N, Ding, S-L, Gouwens, N W, Hodge, R D, Kalmbach, B, Lee, C, Lee, B R, Alfiler, L, Baker, K, Barkan, E, Beller, A, Berry, K, Bertagnolli, D, Bickley, K, Bomben, J, Braun, T, Brouner, K, Casper, T, Chong, P, Crichton, K, Dalley, R, de Frates, R, Desta, T, Lee, S D, D’Orazi, F, Dotson, N, Egdorf, T, Enstrom, R, Farrell, C, Feng, D, Fong, O, Furdan, S, Galakhova, A A, Gamlin, C, Gary, A, Glandon, A, Goldy, J, Gorham, M, Goriounova, N A, Gratiy, S, Graybuck, L, Gu, H, Hadley, K, Hansen, N, Heistek, T S, Henry, A M, Heyer, D B, Hill, D, Hill, C, Hupp, M, Jarsky, T, Kebede, S, Keene, L, Kim, L, Kim, M-H, Kroll, M, Latimer, C, Levi, B P, Link, K E, Mallory, M, Mann, R, Marshall, D, Maxwell, M, McGraw, M, McMillen, D, Melief, E, Mertens, E J, Mezei, L, Mihut, N, Mok, S, Molnar, G, Mukora, A, Ng, L, Ngo, K, Nicovich, P R, Nyhus, J, Olah, G, Oldre, A, Omstead, V, Ozsvar, A, Park, D, Peng, H, Pham, T, Pom, C A, Potekhina, L, Rajanbabu, R, Ransford, S, Reid, D, Rimorin, C, Ruiz, A, Sandman, D, Sulc, J, Sunkin, S M, Szafer, A, Szemenyei, V, Thomsen, E R, Tieu, M, Torkelson, A, Trinh, J, Tung, H, Wakeman, W, Waleboer, F, Ward, K, Wilbers, R, Williams, G, Yao, Z, Yoon, J-G, Anastassiou, C, Arkhipov, A, Barzo, P, Bernard, A, Cobbs, C, de Witt Hamer, P C, Ellenbogen, R G, Esposito, L, Ferreira, M, Gwinn, R P, Hawrylycz, M J, Hof, P R, Idema, S, Jones, A R, Keene, C D, Ko, A L, Murphy, G J, Ng, L, Ojemann, J G, Patel, A P, Phillips, J W, Silbergeld, D L, Smith, K, Tasic, B, Yuste, R, Segev, I, de Kock, C P J, Mansvelder, H D, Tamas, G, Zeng, H, Koch, C & Lein, E S 2021, ' Human neocortical expansion involves glutamatergic neuron diversification ', Nature, vol. 598, no. 7879, pp. 151-158 . https://doi.org/10.1038/s41586-021-03813-8

The neocortex is disproportionately expanded in human compared with mouse1,2, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons that selectively make connections wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c41f5015a297892f279cb761e2d9f21
https://hdl.handle.net/1871.1/df908a46-b182-41b3-b732-326dddbab23b

Association of traumatic brain injury with late life neuropathological outcomes in a community‐based cohort

Autor: Allison Beller, Caitlin S. Latimer, Rod L. Walker, Erica J. Melief, Raj G. Kumar, Alia E Murphy, C. Dirk Keene, Paul K. Crane, Eric B. Larson, Melinda C. Power, Kristen Dams-O'Connor, Laura E. Gibbons

Publikováno v: Alzheimer's & Dementia. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2845d6941c5f5af213a9844c8e514f14
https://doi.org/10.1002/alz.041939

Human cortical expansion involves diversification and specialization of supragranular intratelencephalic-projecting neurons

Autor: Sergey L. Gratiy, Sara Kebede, Chris Hill, Clare Gamlin, Jeffrey G. Ojemann, Tom Egdorf, Ed S. Lein, Lydia Potekhina, Alice Mukora, Shea Ransford, Matthew Mallory, Tim S. Heistek, Jonathan T. Ting, Gábor Tamás, Philip C. De Witt Hamer, Rebecca de Frates, Medea McGraw, Gábor Molnár, Jim Berg, Szabina Furdan, Patrick R. Hof, Natalia A. Goriounova, David Feng, David Reid, Elliot R. Thomsen, Michael Tieu, Katelyn Ward, C. Dirk Keene, Florence D’Orazi, Mean Hwan Kim, Daniel Park, Amy Torkelson, Agata Budzillo, Katherine Baker, Michael Hawrylycz, Krissy Brouner, Andrew L. Ko, DiJon Hill, Kyla Berry, Peter Chong, Jessica Trinh, Desiree A. Marshall, Katherine E. Link, Brian Lee, Jasmine Bomben, Aaron Szafer, Gabe J. Murphy, Viktor Szemenyei, Madie Hupp, Lauren Alfiler, Nick Dee, Zizhen Yao, Luke Esposito, Tamara Casper, Erica J. Melief, Susan M. Sunkin, Lindsay Ng, Hongkui Zeng, Pál Barzó, Allison Beller, Lydia Ng, Charles Cobbs, Darren Bertagnolli, Kiet Ngo, Bosiljka Tasic, John W. Phillips, Christine Rimorin, Alex M. Henry, Aaron Oldre, Michelle Maxwell, Wayne Wakeman, Delissa McMillen, Amanda Gary, Tsega Desta, Nathan Hansen, Hong Gu, Julie Nyhus, Staci A. Sorensen, Gáspár Oláh, Thomas Chartrand, Kirsten Crichton, Matthew Kroll, Josef Sulc, Jeremy A. Miller, Amy Bernard, Lisa Kim, Herman Tung, Idan Segev, Kristen Hadley, David Sandman, Anoop P. Patel, Colin Farrell, Allan R. Jones, Lisa Keene, Sander Idema, Changkyu Lee, Stephanie Mok, Augustin Ruiz, Caitlin S. Latimer, Tim Jarsky, Kris Bickley, Anton Arkhipov, Ramkumar Rajanbabu, Thomas Braun, Costas A. Anastassiou, Anatoly Buchin, Nathan W. Gouwens, Philip R. Nicovich, Richard G. Ellenbogen, Olivia Fong, Grace Williams, Rachel Enstrom, Rachel A. Dalley, Daniel L. Silbergeld, Attila Ozsvár, Kimberly A. Smith, Ryder P. Gwinn, Songlin Ding, Rafael Yuste, Manuel Ferreira, Victoria Omstead, Samuel Dingman Lee, Norbert Mihut, Hanchuan Peng, Brian E. Kalmbach, Eliza Barkan, Melissa Gorham, Boaz P. Levi, Trygve E. Bakken, Jeff Goldy, Djai B. Heyer, Nadezhda Dotson, Rusty Mann, Rebecca D. Hodge, Christof Koch, René Wilbers, Leona Mezei, Eline J. Mertens, Jae-Geun Yoon, Anna A. Galakhova, Christina A. Pom, Trangthanh Pham, Alexandra Glandon, Christiaan P. J. de Kock, Lucas T. Graybuck, Huibert D. Mansvelder

The neocortex is disproportionately expanded in human compared to mouse, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers that selectively make connections within the cortex and other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b6d63820fb05a354d1dab2b84fb32f

Conserved cell types with divergent features in human versus mouse cortex

Autor: Elliot R. Thomsen, Ahmed Mahfouz, Saroja Somasundaram, Aaron Oldre, Bosiljka Tasic, Songlin Ding, Richard H. Scheuermann, Daniel Hirschstein, Thomas Höllt, Christine Rimorin, Thuc Nghi Nguyen, Jennie L. Close, John W. Phillips, Lydia Ng, Jeff Goldy, Darren Bertagnolli, Amy Bernard, Zizhen Yao, Boaz P. Levi, Trygve E. Bakken, Soraya I. Shehata, Susan M. Sunkin, Osnat Penn, Michael Tieu, Allison Beller, Boudewijn P. F. Lelieveldt, Jeffrey G. Ojemann, Shannon Reynolds, Michael Hawrylycz, Jeroen Eggermont, Medea McGraw, Ryder P. Gwinn, Sheana Parry, Kimberly A. Smith, Brian Long, Olivia Fong, Zoe Maltzer, Rafael Yuste, David Feng, Julie Nyhus, Rebecca D. Hodge, Ed Lein, Jeremy A. Miller, Brian D. Aevermann, Gerald Quon, Emma Garren, Christof Koch, Aaron Szafer, Nick Dee, Nadiya V. Shapovalova, Rachel A. Dalley, Tamara Casper, Mohamed Keshk, Nelson Johansen, Krissy Brouner, Andrew L. Ko, Allan R. Jones, Eliza Barkan, Hongkui Zeng, Richard G. Ellenbogen, C. Dirk Keene, Kanan Lathia, Lucas T. Graybuck, Charles Cobbs

Publikováno v: Nature, vol 573, iss 7772
Nature, 573(7772), 61

Elucidating the cellular architecture of the human cerebral cortex is central to understanding our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-sequencing analysis to perform a comprehensive study of cell types i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cb2e1e03c5b89538fe61c3d31c48fc
https://doi.org/10.1038/s41586-019-1506-7

Selectively Impaired Vasodilation of Human White Matter Penetrating Cerebral Arterioles in Microvascular Brain Injury and Alzheimer's disease

Autor: Thuan D. Ngyuen, Allison Beller, Thomas J. Montine, David Fulton, C. Dirk Keene, Eric Larson, Dieter D. Brander, Phuong D. Le, David D. McNeal, Zsolt Bagi, Stephen D. Back, Huijuan Dou, Xi D. Gong

Publikováno v: The FASEB Journal. 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::882b69c332affe90e962c59ca51c6309
https://doi.org/10.1096/fasebj.2018.32.1_supplement.711.15