Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers

Autor: Eric D. Laing, Carol D. Weiss, Emily C. Samuels, Si’Ana A. Coggins, Wei Wang, Richard Wang, Russell Vassell, Spencer L. Sterling, Marana S. Tso, Tonia Conner, Emilie Goguet, Matthew Moser, Belinda M. Jackson-Thompson, Luca Illinik, Julian Davies, Orlando Ortega, Edward Parmelee, Monique Hollis-Perry, Santina E. Maiolatesi, Gregory Wang, Kathleen F. Ramsey, Anatalio E. Reyes, Yolanda Alcorta, Mimi A. Wong, Alyssa R. Lindrose, Christopher A. Duplessis, David R. Tribble, Allison M.W. Malloy, Timothy H. Burgess, Simon D. Pollett, Cara H. Olsen, Christopher C. Broder, Edward Mitre

Publikováno v: Emerging Infectious Diseases, Vol 28, Iss 4, Pp 828-832 (2022)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 ex

Externí odkaz: https://doaj.org/article/1cd8ef6923d34344817f8a6b6fe3a799

1056. Correlates of Omicron SARS-CoV-2 viral load: diagnostic and clinical implications

Autor: Simon Pollett, Stephanie A Richard, Anthony C Fries, Allison M Malloy, Anuradha Ganesan, Jeffrey Livezey, David Saunders, Nikhil Huprikar, Rupal Mody, Katrin Mende, David A Lindholm, Catherine M Berjohn, Julia S Rozman, Milissa Jones, Christopher Colombo, Rhonda E Colombo, David Tribble, Mark P Simons, Brian Agan, Timothy Burgess

Publikováno v: Open Forum Infectious Diseases. 9

Background Omicron SARS-CoV-2 infections are associated with less frequent olfactory sensory loss and a predominance of pharyngitis symptoms compared to prior variants, with proposed diagnostic implications. We examined whether such symptomology pred

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd8b4442441a89dac7110421fa6fd969
https://doi.org/10.1093/ofid/ofac492.897

Distinct innate signaling and activation of dendritic cells during the neonatal period determines their functional response to respiratory syncytial virus infection

Autor: Annie W Lau-Kilby, Margaret Kehl, Allison MW Malloy

Publikováno v: The Journal of Immunology. 198:203.4-203.4

Dendritic cells (DCs) are among the first to respond to infection, providing the critical link between innate and adaptive immunity. Neonates often have weak innate immune responses that can limit adaptive immunity and contribute to increased suscept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07eb86637be20db27864383f8bf3ca1f
https://doi.org/10.4049/jimmunol.198.supp.203.4

High baseline frequencies of natural killer cells are associated with asymptomatic SARS-CoV-2 infection

Autor: Elizabeth K. Graydon, Allison M.W. Malloy, Kawthar Machmach, Peifang Sun, Dominic Paquin-Proulx, Stephen Lizewski, Rhonda Lizewski, Dawn L. Weir, Carl W. Goforth, Stephen K. Anderson, Andrew G. Letizia, Edward Mitre

Publikováno v: Current Research in Immunology, Vol 4, Iss , Pp 100064- (2023)

This study tested the hypothesis that high frequencies of natural killer (NK) cells are protective against symptomatic SARS-CoV-2 infection. Samples were utilized from the COVID-19 Health Action Response for Marines study, a prospective, observationa

Externí odkaz: https://doaj.org/article/4bfc31955d084980a10a82d06946100c

Precision symptom phenotyping identifies early clinical and proteomic predictors of distinct COVID-19 sequelae.

Autor: Epsi NJ; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Chenoweth JG; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Blair PW; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.; Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Lindholm DA; Brooke Army Medical Center, San Antonio, TX, USA.; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Ganesan A; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.; Walter Reed National Military Medical Center, Bethesda, MD, USA., Lalani T; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.; Naval Medical Center Portsmouth, Portsmouth, VA, USA., Smith A; Naval Medical Center Portsmouth, Portsmouth, VA, USA., Mody RM; William Beaumont Army Medical Center, El Paso, TX, USA., Jones MU; Tripler Army Medical Center, Honolulu, HI, USA., Colombo RE; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Madigan Army Medical Center, Tacoma, WA, USA., Colombo CJ; Madigan Army Medical Center, Tacoma, WA, USA., Schofield C; Madigan Army Medical Center, Tacoma, WA, USA., Ewers EC; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Tripler Army Medical Center, Honolulu, HI, USA.; Alexander T. Augusta Military Medical Center, VA, USA., Larson DT; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Alexander T. Augusta Military Medical Center, VA, USA.; Naval Medical Center San Diego, San Diego, CA, USA., Berjohn CM; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Naval Medical Center San Diego, San Diego, CA, USA., Maves RC; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Wake Forest University School of Medicine, Winston-Salem, NC, USA., Fries AC; U.S. Air Force School of Aerospace Medicine, Dayton, OH, USA., Chang D; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Alexander T. Augusta Military Medical Center, VA, USA., Wyatt A; Landstuhl Regional Medical Center, Landstuhl, Germany., Scher AI; Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Byrne C; Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Rusiecki J; Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Saunders DL; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Livezey J; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Malloy A; Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Bazan S; Carl R. Darnall Army Medical Center, Fort Cavazos, TX, USA., Maldonado C; Womack Army Medical Center, Fort Liberty, NC, USA., Edwards MS; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Mende K; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.; Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Simons MP; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., O'Connell RJ; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Tribble DR; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Agan BK; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Burgess TH; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Pollett SD; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Richard SA; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.