Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Allison, Doyle"'
Autor:
Allison Doyle Brackley, Ruben Gomez, Kristi A. Guerrero, Armen N. Akopian, Marc J. Glucksman, Junhui Du, Susan M. Carlton, Nathaniel A. Jeske
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Mechanical pain serves as a base clinical symptom for many of the world’s most debilitating syndromes. Ion channels expressed by peripheral sensory neurons largely contribute to mechanical hypersensitivity. Transient Receptor Potential A 1
Externí odkaz:
https://doaj.org/article/78d62c56f9cc4d618d2eefe60eaa2041
Publikováno v:
Journal of Neurochemistry. 162:156-165
Inflammatory hyperalgesia represents a nociceptive phenotype that can become persistent in nature through dynamic protein modifications. However, a large gap in knowledge exists concerning how the integration of intracellular signaling molecules coor
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2686-2698 (2016)
Opioids remain the standard for analgesic care; however, adverse effects of systemic treatments contraindicate long-term administration. While most clinical opioids target mu opioid receptors (MOR), those that target the delta class (DOR) also demons
Externí odkaz:
https://doaj.org/article/69b6dfbb4b994fe0a7a7f55e19607177
Autor:
Sakaorat Lertjuthaporn, Claudia Cicala, Donald Van Ryk, Matthew Liu, Jason Yolitz, Danlan Wei, Fatima Nawaz, Allison Doyle, Brooke Horowitch, Chung Park, Shan Lu, Yang Lou, Shixia Wang, Ruimin Pan, Xunqing Jiang, Francois Villinger, Siddappa N Byrareddy, Philip J Santangelo, Lynn Morris, Constantinos Kurt Wibmer, Kristin Biris, Rosemarie D Mason, Jason Gorman, Joseph Hiatt, Elena Martinelli, Mario Roederer, Dai Fujikawa, Giacomo Gorini, Genoveffa Franchini, Anush Arakelyan, Aftab A Ansari, Kovit Pattanapanyasat, Xiang-Peng Kong, Anthony S Fauci, James Arthos
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007278 (2018)
The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synth
Externí odkaz:
https://doaj.org/article/1d27a974a42f4d20a2e0217100ce0387
Autor:
Elaine D Por, Melody L Sandoval, Chiquita Thomas-Benson, Teresa A Burke, Allison Doyle Brackley, Nathaniel A Jeske, Jeffery M Cleland, Brian J Lund
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182102 (2017)
Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor po
Externí odkaz:
https://doaj.org/article/69724b78f4d5470f9fec116a82b2d094
Autor:
Allison Doyle Brackley, Glenn M. Toney
Publikováno v:
J Pharmacol Exp Ther
Opioid overdose intervention by naloxone, a high affinity receptor antagonist, reverses opioid-induced respiratory depression (OIRD) and analgesia by displacing opioids. Systemic naloxone stimulates release of the hypothalamic neuropeptide oxytocin,
Autor:
Allison Doyle, Lakshmi Goparaju, Mary Ann Dutton, Katherine G. Michel, Mikayla Cochrane, Anjali Kikkisetti, Daniel Merenstein, Seble Kassaye, Amanda B. Spence, Katheryn Bell, Lucile L. Adams-Campbell, Kathryn A. Lee, Cuiwei Wang
Publikováno v:
AIDS Patient Care STDS
The goal of HIV treatment is viral suppression as it is linked with improved health outcomes and decreased risk of viral transmission. We assessed the sociodemographic, behavioral, and patient-provider interaction associations with viral suppression
Akademický článek
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Autor:
Sophie, Yang, Amy, Geller, Alina, Baciu, Alex, Akman, Melissa, Aune, Rachel, Bailey, Jennifer, Breau, Eric, Cal, Mc Millan, Ching, Emanuel, Demissie, Allison, Doyle, Dominique, Earland, Calie, Edmonds, Ngozi, Elobuike, Garrett, Forrester, Hallie, Fox, Ikwo, Frank, George, Gilliam, Lcdr Shawna, Grover, An, Harmanli, Christine, Hill, Lt Breda, Jenkins, Guzal, Khayrullina, Caroline, King, Lt Vidya, Lala, Ens Michelle, Mandeville, Noah, Martin, Paige, Miles, Alexander, Murray, Chigoziem, Oguh, Elizabeth, Pham, Tim, Putnam, Maya, Rashad, Emily, Shaffer, Maj Tonya, Spencer, Ben, Szulanczyk, Elizabeth, Taormina, Erin, Teigen, Tisa, Thomas, Adrienne, Thomas, Kimberly, Vilmenay
Publikováno v:
NAM Perspect
Publikováno v:
eNeuro.
There are currently no Food and Drug Administration (FDA)-approved δ-opioid receptor (DOR)-selective agonists, despite having fewer side effects in rodents and nonhuman primates compared with traditional μ-opioid receptor (MOR) therapeutics (Vander