Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Allison, Blackorby"'
Autor:
Iain C. Macdougall, Amy Mewborn Meadowcroft, Allison Blackorby, BORUT Cizman, Alexander R Cobitz, Sergio Godoy, Vivekanand Jha, Kirsten L. Johansen, Gearoid McMahon, Gregorio T. Obrador, Muh Geot Wong, Ajay K. Singh
Publikováno v:
American Journal of Nephrology.
Introduction: Hyporesponsiveness to erythropoiesis-stimulating agents (ESAs) affects 10–15% of the chronic dialysis population. We explored baseline characteristics and predictors of ESA hyporesponsiveness in a global randomized cardiovascular outc
Autor:
Vlado Perkovic, Allison Blackorby, Borut Cizman, Kevin Carroll, Alexander R Cobitz, Rich Davies, Tara L DiMino, Vivekanand Jha, Kirsten L Johansen, Renato D Lopes, Lata Kler, Iain C Macdougall, John J V McMurray, Amy M Meadowcroft, Gregorio T Obrador, Scott Solomon, Lin Taft, Christoph Wanner, Sushrut S Waikar, David C Wheeler, Andrzej Wiecek, Ajay K Singh
Publikováno v:
Nephrology Dialysis Transplantation. 37:2157-2170
Background Anaemia is common in chronic kidney disease (CKD) and assessment of the risks and benefits of new therapies is important. Methods The Anaemia Study in CKD: Erythropoiesis via a Novel prolyl hydroxylase inhibitor Daprodustat-Non-Dialysis (A
Autor:
Ajay K Singh, Finnian R Mc Causland, Brian L Claggett, Christoph Wanner, Andrzej Wiecek, Michael B Atkins, Kevin Carroll, Vlado Perkovic, John J V McMurray, Janet Wittes, Steven Snapinn, Allison Blackorby, Amy Meadowcroft, Tara Barker, Tara DiMino, Stephen Mallett, Alexander R Cobitz, Scott D Solomon
Publikováno v:
Nephrology Dialysis Transplantation.
Background The prespecified on-treatment analysis of ASCEND-ND (NCT02876835) raised concerns about a higher relative risk of cancer-related adverse events (AEs) with daprodustat vs darbepoetin in patients with anaemia of CKD. This concern was not obs
Autor:
Christoph Wanner, Gregorio T. Obrador, Sushrut S. Waikar, Kevin Carroll, Iain C. Macdougall, Rich Davies, Borut Cizman, Scott D. Solomon, David C. Wheeler, Alexander R. Cobitz, Andrzej Wiecek, Vivekanand Jha, Kirsten L. Johansen, Lata Kler, Allison Blackorby, Vlado Perkovic, Ajay K. Singh, Renato D. Lopes, John J.V. McMurray, Amy Meadowcroft
Publikováno v:
Nephrology Dialysis Transplantation. 37:960-972
Background The Anemia Studies in chronic kidney disease (CKD): Erythropoiesis via a Novel prolyl hydroxylase inhibitor Daprodustat-Dialysis (ASCEND-D) trial will test the hypothesis that daprodustat is noninferior to comparator epoetin alfa or darbep
Autor:
Ajay K. Singh, Christoph Wanner, Andrzej Jan Wiecek, Allison Blackorby, Tara Barker, Amy Meadowcroft, Alexander Cobitz
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Increased HIF-1 levels are associated with mortality in some cancer patients, and levels of HIF-1 may also impact response to cancer treatments. Use of recombinant human erythropoietin or its analogs [erythropoiesis-stimulating ag
Autor:
Ajay K. Singh, Borut Cizman, Kevin Carroll, John J. V. McMurray, Vlado Perkovic, Vivekanand Jha, Kirsten L. Johansen, Renato D. Lopes, Iain C. Macdougall, Gregorio T. Obrador, Sushrut S. Waikar, Christoph Wanner, David C. Wheeler, Andrzej Wiecek, Nicole Stankus, Frank Strutz, Allison Blackorby, Alexander R. Cobitz, Amy M. Meadowcroft, Gitanjali Paul, Prerna Ranganathan, Sangeeta Sedani, Scott Solomon
Publikováno v:
JAMA internal medicine. 182(6)
Daprodustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, is being evaluated as an oral alternative to conventional erythropoiesis-stimulating agent (ESA) therapy. Few studies of anemia treatment in an incident dialysis (ID) population ha
Autor:
Ajay K, Singh, Kevin, Carroll, Vlado, Perkovic, Scott, Solomon, Vivekanand, Jha, Kirsten L, Johansen, Renato D, Lopes, Iain C, Macdougall, Gregorio T, Obrador, Sushrut S, Waikar, Christoph, Wanner, David C, Wheeler, Andrzej, Więcek, Allison, Blackorby, Borut, Cizman, Alexander R, Cobitz, Rich, Davies, Jo, Dole, Lata, Kler, Amy M, Meadowcroft, Xinyi, Zhu, John J V, McMurray, Jorge, Posada
Publikováno v:
The New England journal of medicine. 385(25)
Background: \ud Among patients with chronic kidney disease (CKD), the use of recombinant human erythropoietin and its derivatives for the treatment of anemia has been linked to a possibly increased risk of stroke, myocardial infarction, and other adv
Autor:
Christoph Wanner, Kirsten L. Johansen, Borut Cizman, Andrzej Wiecek, Tara L DiMino, David C. Wheeler, Richard Davies, Ajay K. Singh, Allison Blackorby, Lin Taft, Iain C. Macdougall, Kevin Carroll, Scott D. Solomon, John J.V. McMurray, Vlado Perkovic, Lata Kler, Gregorio T. Obrador, Sushrut S. Waikar, Amy Meadowcroft, Alexander R. Cobitz, Renato D. Lopes, Vivekanand Jha
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The Anemia Study in Chronic kidney disease (CKD): Erythropoiesis via a Novel prolyl hydroxylase inhibitor (PHI) Daprodustat-Non-Dialysis (ASCEND-ND; NCT02876835) trial is evaluating the efficacy and safety of daprodustat when comp