Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Allie J. Widman"'
Autor:
Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J. Widman, Robert J. Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Waylin Yu, Thomas L. Kash, Robert W. Gereau, Jose A. Morón
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The hippocampus is pivotal in integrating emotional processing, learning, memory, and reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for episodic, spatial, and associative memory, and has been shown to be nec
Externí odkaz:
https://doaj.org/article/87fdb1df68f64020b4bcdb032e7d7959
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
In the past 20 years, ketamine has become a promising treatment for Major Depressive Disorder (MDD) due to its rapid and sustain antidepressant effects in patients. A single ketamine treatment causes improvement in depressive symptoms within hours an
Externí odkaz:
https://doaj.org/article/966b0a9000fd42f0a9f1487565054832
Autor:
Jiwon Yi, Zachariah Bertels, John Smith Del Rosario, Allie J. Widman, Richard A. Slivicki, Maria Payne, Henry M. Susser, Bryan A. Copits, Robert W. Gereau
Publikováno v:
bioRxiv
Bradykinin is a peptide implicated in inflammatory pain in both humans and rodents. In rodent sensory neurons, activation of B1 and B2 bradykinin receptors induces neuronal hyperexcitability. Recent evidence suggests that human and rodent dorsal root
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055c5691c74fd1c3fcb2b45ec1f1cdd5
https://doi.org/10.1101/2023.03.31.534820
https://doi.org/10.1101/2023.03.31.534820
Autor:
Jiwon Yi, Zachariah Bertels, John Del Rosario, Richard A. Slivicki, Allie J. Widman, Robert W. Gereau
Publikováno v:
The Journal of Pain. 23:14
Autor:
Allie J, Widman, Lori L, McMahon
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 89
A single sub-anesthetic intravascular dose of the use-dependent NMDAR antagonist, ketamine, improves mood in patients with treatment resistant depression within hours that can last for days, creating an entirely new treatment strategy for the most se
Autor:
Allie J. Widman, Lori L. McMahon
A single sub-anesthetic intravascular dose of the use-dependent NMDAR antagonist, ketamine, improves mood in patients with treatment resistant depression within hours that can last for days, creating an entirely new treatment strategy for the most se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dea9c40b4e30a3bdda4dd76c121b805
https://doi.org/10.1016/bs.apha.2020.05.001
https://doi.org/10.1016/bs.apha.2020.05.001
Autor:
Lori L. McMahon, Matthew E. Glover, Joshua L. Cohen, Allie J. Widman, Anas U. Khan, Chelsea R. McCoy, Teruko M. Bredemann, Sarah M. Clinton, Keaton A. Unroe
Publikováno v:
Hippocampus
The hippocampus is essential for learning and memory but also regulates emotional behavior. We previously identified the hippocampus as a major brain region that differs in rats bred for emotionality differences. Rats bred for low novelty response (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc88f38108a258756b0a4186d747d87
https://europepmc.org/articles/PMC7377203/
https://europepmc.org/articles/PMC7377203/
Autor:
Lori L. McMahon, Allie J. Widman
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Low-dose ketamine, an open-channel N-methyl d-aspartate receptor (NMDAR) antagonist, mediates rapid antidepressant effects in humans that are mimicked in preclinical rodent models. Disinhibition of pyramidal cells via decreased output of fast-spiking
Autor:
Dennis R. Sparta, Allie J. Widman, Felipe Espinosa, Mihaela Stavarache, Antonello Bonci, Kay M. Tye, Garret D. Stuber, Craig M. Powell, Luis F. Parada, Scott J. Russo, Michael E. Haws, Michael G. Kaplitt, Thomas C. Jaramillo
Publikováno v:
Journal of Comparative Neurology. 522:1171-1190
Mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) are implicated in neuropsychiatric disorders including autism. Previous studies report that PTEN knockdown in neurons in vivo leads to increased spine density and synaptic ac
Autor:
Haley E. Speed, Jeremy M. Reimers, Natasha Gupta, Muhammad Bangash, Shunan Liu, Bo Xiao, Allie J. Widman, Thomas C. Jaramillo, Paul F. Worley, Colleen M. Dewey, Mehreen Kouser, Craig M. Powell
Publikováno v:
The Journal of Neuroscience. 33:18448-18468
TheShank3gene encodes a scaffolding protein that anchors multiple elements of the postsynaptic density at the synapse. Previous attempts to delete theShank3gene have not resulted in a complete loss of the predominant naturally occurring Shank3 isofor