Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Allie C Obermeyer"'
Autor:
So Yeon Ahn, Allie C. Obermeyer
Publikováno v:
JACS Au, Vol 4, Iss 10, Pp 3800-3812 (2024)
Externí odkaz:
https://doaj.org/article/a15d4a6dc7c04f1ab7545132bdc5cfc4
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100678 (2014)
Thrombosis is the cause of many cardiovascular syndromes and is a significant contributor to life-threatening diseases, such as myocardial infarction and stroke. Thrombus targeted imaging agents have the capability to provide molecular information ab
Externí odkaz:
https://doaj.org/article/e3afe9dfda6248c7b5f455ba607a03a1
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Phase separation provides intracellular organisation via membraneless entities called biomolecular condensates. Here, the authors show that short, cationic peptide tags can drive biomolecular condensation of engineered proteins in E. coli through ass
Externí odkaz:
https://doaj.org/article/66304a03ea624f1f9a0cac7576142e6e
Publikováno v:
ACS Central Science, Vol 6, Iss 12, Pp 2301-2310 (2020)
Externí odkaz:
https://doaj.org/article/fa45f0c884814b8d96a4e61d06e7a125
Publikováno v:
Journal of the American Chemical Society. 145:6554-6561
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84b32f25e304f366e39d339f54d973f
https://doi.org/10.1021/jacs.3c00883
https://doi.org/10.1021/jacs.3c00883
Autor:
Nisha Modi, Siwei Chen, Imelda N. A. Adjei, Briana L. Franco, Kyle J. M. Bishop, Allie C. Obermeyer
Publikováno v:
Chemical Science. 14:4735-4744
Two-way coupling between pH-responsive phase separation of enzyme-polymer mixtures and reaction-induced pH changes creates negative feedback in these active coacervates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df522e236ca61744f150f53c522b63aa
https://doi.org/10.1039/d2sc03838b
https://doi.org/10.1039/d2sc03838b
Publikováno v:
Soft matter. 18(31)
Intrinsically disordered polypeptides are a versatile class of materials, combining the biocompatibility of peptides with the disordered structure and diverse phase behaviors of synthetic polymers. Synthetic polyelectrolytes are capable of complex ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52073a49e357d4f16c12aac2a50a8590
https://pubmed.ncbi.nlm.nih.gov/35912826
https://pubmed.ncbi.nlm.nih.gov/35912826
Autor:
Nicholas Zervoudis, Allie C. Obermeyer
Publikováno v:
Soft Matter. 17:6637-6645
The complex coacervation of proteins with other macromolecules has applications in protein encapsulation and delivery and for determining the function of cellular coacervates. Theoretical or empirical predictions for protein coacervates would enable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676dc4c3f301dc74d60ed7ff7975b345
https://doi.org/10.1039/d1sm00543j
https://doi.org/10.1039/d1sm00543j
Publikováno v:
ACS Central Science
ACS Central Science, Vol 6, Iss 12, Pp 2301-2310 (2020)
ACS Central Science, Vol 6, Iss 12, Pp 2301-2310 (2020)
While eukaryotic cells have a myriad of membrane-bound organelles enabling the isolation of different chemical environments, prokaryotic cells lack these defined reaction vessels. Biomolecular condensates—organelles that lack a membrane—provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdc0a6ff7e5866f12315178006c920d
https://doi.org/10.1021/acscentsci.0c01146
https://doi.org/10.1021/acscentsci.0c01146
Publikováno v:
Chemical science. 13(48)
Proteins are an important class of biologics, but there are several recurring challenges to address when designing protein-based therapeutics. These challenges include: the propensity of proteins to aggregate during formulation, relatively low loadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5c2472d76222e0753dc09f03b16d65
https://pubmed.ncbi.nlm.nih.gov/36545145
https://pubmed.ncbi.nlm.nih.gov/36545145