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pro vyhledávání: '"Allgeier Matthew Carl"'
Autor:
Phenil J. Patel, Christopher Breslin, Michael Koenig, Aaron Zettler, Jon Hilden, Aktham Aburub, Allgeier Matthew Carl, Biplob Mitra
Publikováno v:
Journal of Pharmaceutical Innovation. 11:189-199
In pharmaceutical development, powder flow characteristics are notoriously difficult to predict. Although tests exist that aim to determine the flowability of powders, many have not been definitively correlated with a powder’s performance in downst
Autor:
Jeremy Hinds, David Michael Remick, Matthew H. Yates, Jared L. Piper, Kevin J. Kolodsick, Bruce Shaw, Mehuli R. Kulkarni, Allgeier Matthew Carl, Richard H. Meury
Publikováno v:
Journal of pharmaceutical sciences. 105(10)
Control and optimization of the physical properties of a drug substance (DS) are critical to the development of robust drug product manufacturing processes and performance. A lack of isolatable, for example, crystalline, DS solid forms can present ch
Autor:
J. Hofer, Allgeier Matthew Carl, Nick Toltl, S. Peoples, B. Bustard, Timothy L. Shelbourn, M. Foubert, Xia Dong, Ronald G. Iacocca
Publikováno v:
AAPS PharmSciTech. 11:1340-1349
Delamination, or the generation of glass flakes in vials used to contain parenteral drug products, continues to be a persistent problem in the pharmaceutical industry. To understand all of the factors that might contribute to delamination, a statisti
Publikováno v:
Journal of Materials Science. 42:801-811
Glass delamination, or the generation of glass flakes, continues to be an unwanted occurrence in the manufacture of parenteral (injectable) solutions and suspensions. In this root cause analysis study, advanced analytical tools including atomic force
Publikováno v:
Science. 279:545-548
The dynamics of dangling bond (DB) diffusion was studied after deuterium desorption from the silicon (100)-2×1 surface. At elevated temperatures, paired DB sites produced after desorption unpaired as deuterium atoms hopped from adjacent dimers. Belo