"Methylene Bridge" to 5‑HT3 Receptor Antagonists: Conformationally Constrained Phenylguanidines.

Autor: Abdelkhalek, Ahmed S., Alley, Genevieve S., Alwassil, Osama I., Khatri, Shailesh, Mosier, Philip D., Nyce, Heather L., White, Michael M., Schulte, Marvin K., Dukat, Małgorzata

Publikováno v: ACS Chemical Neuroscience; Mar2019, Vol. 10 Issue 3, p1380-1389, 10p

"Methylene Bridge" to 5-HT 3 Receptor Antagonists: Conformationally Constrained Phenylguanidines.

Autor: Abdelkhalek AS; Department of Medicinal Chemistry, School of Pharmacy , Virginia Commonwealth University , Richmond , Virginia 23298 , United States., Alley GS; Department of Medicinal Chemistry, School of Pharmacy , Virginia Commonwealth University , Richmond , Virginia 23298 , United States., Alwassil OI; Department of Medicinal Chemistry, School of Pharmacy , Virginia Commonwealth University , Richmond , Virginia 23298 , United States., Khatri S; Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy , University of the Sciences , Philadelphia , Pennsylvania 19104 , United States., Mosier PD; Department of Medicinal Chemistry, School of Pharmacy , Virginia Commonwealth University , Richmond , Virginia 23298 , United States., Nyce HL; Department of Biochemistry and Molecular Biology , College of Medicine, Drexel University , Philadelphia , Pennsylvania 19102 , United States., White MM; Department of Biochemistry and Molecular Biology , College of Medicine, Drexel University , Philadelphia , Pennsylvania 19102 , United States., Schulte MK; Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy , University of the Sciences , Philadelphia , Pennsylvania 19104 , United States., Dukat M; Department of Medicinal Chemistry, School of Pharmacy , Virginia Commonwealth University , Richmond , Virginia 23298 , United States.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2019 Mar 20; Vol. 10 (3), pp. 1380-1389. Date of Electronic Publication: 2018 Nov 08.