Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Allergic lung disease"'
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Respiratory fungal exposure is known to be associated with various allergic pulmonary disorders. Eosinophils have been implicated in tissue homeostasis of allergic inflammation as both destructive effector cells and immune regulat
Externí odkaz:
https://doaj.org/article/c3e6f64ec4764f419a02708a0f52ca71
Akademický článek
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Autor:
Balbino, Bianca
A tolerância pode ser considerada um dos pilares da imunologia. Sabe-se que a tolerância a um antígeno pode gerar tolerância a outro antígeno não relacionado, fenômeno conhecido como tolerância cruzada. Neste trabalho caracterizamos a tolerâ
Autor:
Timothy S. C. Hinks, Ian D. Pavord, J Melhorn, Sanjay Ramakrishnan, Simon Couillard, Annette Laugerud, M Jabeen
Publikováno v:
Thorax
Reduction of the risk of asthma attacks is a major goal of current asthma management. We propose to derive a risk scale predicting asthma attacks based on the blood eosinophil count and exhaled nitric oxide (FeNO). Biomarker-stratified trial-level at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e906ed79be8ce4873e1bbf928e691ed
https://doi.org/10.1136/thoraxjnl-2021-217325
https://doi.org/10.1136/thoraxjnl-2021-217325
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Respiratory Research
Respiratory Research
Background Respiratory fungal exposure is known to be associated with various allergic pulmonary disorders. Eosinophils have been implicated in tissue homeostasis of allergic inflammation as both destructive effector cells and immune regulators. What
Autor:
David McCoy, Gerome Breen, Sultan Saeed Rajpoot, Bodrul Alam, Jane Symons, Jed Ashman, Sarah El Rifai, Gwyneth A. Davies, Katherine N. Thompson, Paul E Pfeffer, Mohammad Talaei, Olivia Timmis, Chris Griffiths, Molly R. Davies, Katherine S. Young, Graham Lloyd-Jones, Sarah Finer, David A. Jolliffe, Frank Kee, Hayley Holt, Nicholas S Hopkinson, Adrian R. Martineau, Dominik Zenner, Thomas Dietrich, Iain L. C. Chapple, Alec Miners, Seif O. Shaheen, Stamatina Iliodromiti, Philippa J. Lloyd, Ronan A Lyons, Clare Relton, Aziz Sheikh, Matthew Greenig, Ahmed Ali Kayyale
Publikováno v:
Thorax
Holt, H, Talaei, M, Greenig, M, Zenner, D, Symons, J, Relton, C, Young, K S, Davies, M R, Thompson, K N, Ashman, J, Rajpoot, S S, Kayyale, A A, El Rifai, S, Lloyd, P J, Jolliffe, D, Timmis, O, Finer, S, Iliodromiti, S, Miners, A, Hopkinson, N S, Alam, B, Lloyd-Jones, G, Dietrich, T, Chapple, I, Pfeffer, P E, McCoy, D, Davies, G, Lyons, R A, Griffiths, C, Kee, F, Sheikh, A, Breen, G, Shaheen, S O & Martineau, A R 2021, ' Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) ', Thorax . https://doi.org/10.1136/thoraxjnl-2021-217487
Holt, H, Talaei, M, Greenig, M, Zenner, D, Symons, J, Relton, C, Young, K S, Davies, M R, Thompson, K N, Ashman, J, Rajpoot, S S, Ali Kayyale, El Rifai, S, Lloyd, P J L, Jolliffe, D, Timmis, O, Finer, S, Iliodromiti, S, Miners, A, Hopkinson, N S, Alam, B, Lloyd-Jones, G, Dietrich, T, Chapple, I, Pfeffer, P E, McCoy, D, Davies, G, Lyons, R A, Griffiths, C, Kee, F, Sheikh, A, Breen, G, Shaheen, S O & Martineau, A R 2021, ' Risk factors for developing COVID-19 : a population-based longitudinal study (COVIDENCE UK) ', Thorax . https://doi.org/10.1136/thoraxjnl-2021-217487
Holt, H, Talaei, M, Greenig, M, Zenner, D, Symons, J, Relton, C, Young, K S, Davies, M R, Thompson, K N, Ashman, J, Rajpoot, S S, Kayyale, A A, El Rifai, S, Lloyd, P J, Jolliffe, D, Timmis, O, Finer, S, Iliodromiti, S, Miners, A, Hopkinson, N S, Alam, B, Lloyd-Jones, G, Dietrich, T, Chapple, I, Pfeffer, P E, McCoy, D, Davies, G, Lyons, R A, Griffiths, C, Kee, F, Sheikh, A, Breen, G, Shaheen, S O & Martineau, A R 2021, ' Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) ', Thorax . https://doi.org/10.1136/thoraxjnl-2021-217487
Holt, H, Talaei, M, Greenig, M, Zenner, D, Symons, J, Relton, C, Young, K S, Davies, M R, Thompson, K N, Ashman, J, Rajpoot, S S, Ali Kayyale, El Rifai, S, Lloyd, P J L, Jolliffe, D, Timmis, O, Finer, S, Iliodromiti, S, Miners, A, Hopkinson, N S, Alam, B, Lloyd-Jones, G, Dietrich, T, Chapple, I, Pfeffer, P E, McCoy, D, Davies, G, Lyons, R A, Griffiths, C, Kee, F, Sheikh, A, Breen, G, Shaheen, S O & Martineau, A R 2021, ' Risk factors for developing COVID-19 : a population-based longitudinal study (COVIDENCE UK) ', Thorax . https://doi.org/10.1136/thoraxjnl-2021-217487
BackgroundRisk factors for severe COVID-19 include older age, male sex, obesity, black or Asian ethnicity and underlying medical conditions. Whether these factors also influence susceptibility to developing COVID-19 is uncertain.MethodsWe undertook a
Autor:
Jingang Gui, Ian Dransfield, Jürgen Schwarze, Rodger Duffin, Adriano G. Rossi, Philippe M D Potey, Christopher Haslett, Jennifer M Felton, David A. Dorward, Ruth W. Craig, Christopher D. Lucas, Calum T. Robb, Jennifer A Cartwright
Publikováno v:
Felton, J M, Dorward, D A, Cartwright, J, Potey, P M D, Robb, C T, Gui, J, Craig, R W, Schwarze, J, Haslett, C, Duffin, R, Dransfield, I, Lucas, C D & Rossi, A G 2020, ' Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation ', Thorax, vol. 75, no. 7, pp. 600-605 . https://doi.org/10.1136/thoraxjnl-2019-213204
Thorax
Thorax
Eosinophils are key effector cells in allergic diseases. Here we investigated Mcl-1 (an anti-apoptotic protein) in experimental allergic airway inflammation using transgenic overexpressing human Mcl-1 mice (hMcl-1) and reducing Mcl-1 by a cyclin-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5590db05029951e9c4ed70b8e912cdc2
https://hdl.handle.net/20.500.11820/6740e9e8-1b83-4e77-ae17-b57217d8e829
https://hdl.handle.net/20.500.11820/6740e9e8-1b83-4e77-ae17-b57217d8e829
Autor:
Soon Ha Kim, Hyung Jin Kim, Kyung Bae Lee, Hae Jin Park, Yong Chul Lee, Hern-Ku Lee, Dong Im Kim, Narasaiah Kolliputi, Jae Seok Jeong, Seong H. Cho, So Ri Kim
Publikováno v:
Thorax
BackgroundRespiratory fungal exposure is known to be associated with severe allergic lung inflammation. Airway epithelium is an essential controller of allergic inflammation. An innate immune recognition receptor, nucleotide-binding domain, leucine-r