Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Allen Y. Hong"'
Publikováno v:
Angewandte Chemie (International ed. in English).
We offer a new biogenetic proposal for the origin of the complex alkaloid alstonlarsine A, through rearrangement of the Strychnos alkaloids alstolucines B and F. Further, we provide evidence of the chemical feasibility of this proposal in the facile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3432da40d100da89ad24f233a3fe8b
https://pubmed.ncbi.nlm.nih.gov/36448226
https://pubmed.ncbi.nlm.nih.gov/36448226
Publikováno v:
Journal of the American Chemical Society. 138:5234-5237
A catalytic, enantioselective γ -alkylation of α,β-unsaturated malonates and ketoesters is reported. This strategy entails a highly regio- and enantioselective iridium-catalyzed α-alkylation of an extended enolate, and a subsequent translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb07980c8240c8140b5ae397df2495c1
https://doi.org/10.1021/jacs.6b02153
https://doi.org/10.1021/jacs.6b02153
A Synthesis of Alsmaphorazine B Demonstrates the Chemical Feasibility of a New Biogenetic Hypothesis
Publikováno v:
Journal of the American Chemical Society, vol 137, iss 23
An N-oxide fragmentation/hydroxylamine oxidation/intramolecular 1,3-dipolar cycloaddition cascade efficiently converted an oxidized congener of akuammicine into the complex, hexacyclic architecture of the alsmaphorazine alkaloids. This dramatic struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7bf58f5afdd10b4c5f06251499f550
https://doi.org/10.1021/jacs.5b04686
https://doi.org/10.1021/jacs.5b04686
Autor:
Brian M. Stoltz, Allen Y. Hong
Publikováno v:
Angewandte Chemie. 126:5350-5362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a523012303827cebebfc86a12d5b7e8
https://doi.org/10.1002/ange.201309494
https://doi.org/10.1002/ange.201309494
Autor:
Allen Y. Hong, Brian M. Stoltz
Publikováno v:
European Journal of Organic Chemistry. 2013:2745-2759
All-carbon quaternary stereocenters have posed significant challenges in the synthesis of complex natural products. These important structural motifs have inspired the development of broadly applicable palladium-catalyzed asymmetric allylic alkylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7246cc40c7dcc90f1a90c123e4804078
https://doi.org/10.1002/ejoc.201201761
https://doi.org/10.1002/ejoc.201201761
Driven by a new biogenetic hypothesis, the first total synthesis of alsmaphorazine B and several related indole alkaloids has been achieved. Numerous early approaches proved unsuccessful owing to unproductive side reactivity; nevertheless, they provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e17cf4d76bb2a07d51617cfc0ca0348
https://europepmc.org/articles/PMC5603193/
https://europepmc.org/articles/PMC5603193/
Publikováno v:
ChemInform. 47
A catalytic, enantioselective γ-alkylation of α,β-unsaturated malonates and ketoesters is reported. This strategy entails a highly regio- and enantioselective iridium-catalyzed α-alkylation of an extended enolate, and a subsequent translocation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::045ba50fa33e936e9d346dc76c3ef776
https://doi.org/10.1002/chin.201643165
https://doi.org/10.1002/chin.201643165
Autor:
Allen Y. Hong, Brian M. Stoltz
Publikováno v:
Angewandte Chemie. 124:9812-9816
The first total synthesis of the reported structures of 9-epi-presilphiperfolan-1-ol and presilphiperfolan-1-ol has been achieved. Key steps are a catalytic asymmetric alkylation of a novel diene-containing electrophile followed by a two-carbon ring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224419c819ae6811ad2f8e31e6193dd
https://doi.org/10.1002/ange.201205276
https://doi.org/10.1002/ange.201205276
Autor:
Andrew M. Harned, Allen Y. Hong, Nathan B. Bennett, Michael R. Krout, Brian M. Stoltz, Thomas N. Jensen
Publikováno v:
Angewandte Chemie. 123:2808-2812
A simple protocol for the practical, scalable, catalytic asymmetric synthesis of γ-quaternary acylcyclopentenes in up to 91% overall yield and 92% ee has been developed. The reaction sequence employs a palladium-catalyzed enantioselective alkylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffc542c6f9e743a1ce7547ec5937ff4
https://doi.org/10.1002/ange.201007814
https://doi.org/10.1002/ange.201007814
Autor:
Brian M. Stoltz, Allen Y. Hong
Publikováno v:
ChemInform. 45
Presilphiperfolanols constitute a family of biosynthetically important sesquiterpenes which can rearrange to diverse sesquiterpenoid skeletons. While the origin of these natural products can be traced to simple linear terpene precursors, the details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75013ea31e13201825cb101b3787774b
https://doi.org/10.1002/chin.201428254
https://doi.org/10.1002/chin.201428254