Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Allen W. Mangel"'
Publikováno v:
Cardiology & Vascular Research. 6
Autor:
Niaz Sahibzada, Allen W Mangel, Jaclyn E Tatge, Kenneth L Dretchen, Michael R Franz, Renu Virmani, Richard A Gillis
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0130255 (2015)
For over a century, the behavior of the aorta and other large arteries has been described as passive elastic tubes in which no active contraction occurs in the smooth muscle wall. In response to pulsatile pressure changes, the vessels undergo a 'pass
Externí odkaz:
https://doaj.org/article/705598c356384089b7d4ceac73bf714a
Autor:
Allen W Mangel, K Lothman
Publikováno v:
Journal of Cardiology and Cardiovascular Medicine. 4:199-200
Autor:
Allen W Mangel
Publikováno v:
Journal of Clinical & Experimental Cardiology.
The prevailing view of the behavior of the smooth muscle wall of large arteries is described by the Windkessel hypothesis, in which the wall does not actively contract in synchrony with the cardiac cycle. This hypothesis has predominated for well ove
Autor:
Allen W Mangel, K Lothman
Publikováno v:
Cardiovascular Pharmacology: Open Access.
Autor:
Allen W. Mangel, Sarah Marion
Publikováno v:
Clinical and Experimental Gastroenterology
For decades, it was believed that the diameter of gastrointestinal smooth muscle cells is sufficiently narrow, and that the diffusion of calcium across the plasma membrane is sufficient, to support contractile activity. Thus, depolarization-triggered
Autor:
Allen W Mangel
Publikováno v:
Clinical Investigation. 3:131-136
Irritable bowel syndrome, one of the most common gastrointestinal disorders, is characterized by abdominal pain/discomfort and disturbances in bowel functions. Choosing the correct primary end point in irritable bowel syndrome clinical trials has a p
Autor:
Allen W. Mangel, Claire Ervin
Publikováno v:
Reviews on Recent Clinical Trials. 8:9-22
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders and it is characterized by episodes of abdominal pain and altered bowel functions. The specific bowel disturbances of diarrhea, constipation or an alternation between
Publikováno v:
Patient preference and adherence
Susan H Boklage,1 Allen W Mangel,2 Varun Ramamohan,2 Deirdre Mladsi,2 Tao Wang1 1Otsuka America Pharmaceutical Inc, Princeton, NJ, 2RTI Health Solutions, Research Triangle Park, NC, USA Objective: Previous US-based economic models of noninvasive test
Autor:
Valerie Sl Williams, Allen W Mangel
Publikováno v:
Expert Opinion on Investigational Drugs. 19:1257-1264
Irritable bowel syndrome (IBS) represents one of the most common gastrointestinal disorders, with the diarrhea-predominant form (D-IBS) representing an area of high unmet medical need. One difficulty in identifying suitable treatments for IBS is that