Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Allen W. Chan"'
Autor:
Zijia Yu, Lisa Burback, Olga Winkler, Lujie Xu, Liz Dennett, Eric Vermetten, Andrew Greenshaw, Xin-Min Li, Michaela Milne, Fei Wang, Bo Cao, Ian R. Winship, Yanbo Zhang, Allen W. Chan
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Intense interest surrounds current research on psychedelics, particularly regarding their potential in treating mental health disorders. Various studies suggest a link between the subjective effects produced by psychedelics and their therapeutic effi
Externí odkaz:
https://doaj.org/article/80a659bc5a6741c7a257ea72fab6b96e
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 709 (2024)
Psychosis, defined as a set of symptoms that results in a distorted sense of reality, is observed in several psychiatric disorders in addition to schizophrenia. This paper reviews the literature relevant to the underlying neurobiology of psychosis. T
Externí odkaz:
https://doaj.org/article/15ca02146ff74171b3efbaea600f7648
Autor:
Marja D. Sepers, James P. Mackay, Ellen Koch, Dongsheng Xiao, Majid H. Mohajerani, Allen W. Chan, Amy I. Smith-Dijak, Daniel Ramandi, Timothy H. Murphy, Lynn A. Raymond
Publikováno v:
Neurobiology of Disease, Vol 169, Iss , Pp 105740- (2022)
Huntington disease (HD), a hereditary neurodegenerative disorder, manifests as progressively impaired movement and cognition. Although early abnormalities of neuronal activity in striatum are well established in HD models, there are fewer in vivo stu
Externí odkaz:
https://doaj.org/article/6c6b2a489e66429e9fc1c4156edb5abf
Autor:
Dongsheng Xiao, Matthieu P Vanni, Catalin C Mitelut, Allen W Chan, Jeffrey M LeDue, Yicheng Xie, Andrew CN Chen, Nicholas V Swindale, Timothy H Murphy
Publikováno v:
eLife, Vol 6 (2017)
Understanding the basis of brain function requires knowledge of cortical operations over wide-spatial scales, but also within the context of single neurons. In vivo, wide-field GCaMP imaging and sub-cortical/cortical cellular electrophysiology were u
Externí odkaz:
https://doaj.org/article/9de25531b1aa40acb6408beb0317c071
Autor:
Kenta Funayama, Genki Minamisawa, Nobuyoshi Matsumoto, Hiroshi Ban, Allen W Chan, Norio Matsuki, Timothy H Murphy, Yuji Ikegaya
Publikováno v:
PLoS Biology, Vol 13, Iss 8, p e1002231 (2015)
Animals are constantly exposed to the time-varying visual world. Because visual perception is modulated by immediately prior visual experience, visual cortical neurons may register recent visual history into a specific form of offline activity and li
Externí odkaz:
https://doaj.org/article/ad87428e03a9437489a7ce19dc742b5a
Autor:
Jessica Cait, Kelly M. McNagny, Michael R. Hughes, Diana Canals Hernaez, Matthew R. Zeglinski, Pascal Bernatchez, Allen W. Chan, Calvin D. Roskelley, Sabrina Osterhof, R. Wilder Scott, Timothy H. Murphy, T. Michael Underhill, Alissa Cait, A. Wayne Vogl, David J. Granville
Publikováno v:
Proceedings of the National Academy of Sciences. 116:4518-4527
Podocalyxin (Podxl) is broadly expressed on the luminal face of most blood vessels in adult vertebrates, yet its function on these cells is poorly defined. In the present study, we identified specific functions for Podxl in maintaining endothelial ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6291bdbfa516dfc939cb84c0aaa2c51c
https://doi.org/10.1073/pnas.1814766116
https://doi.org/10.1073/pnas.1814766116
Autor:
Taesup Cho, Jae K Ryu, Changiz Taghibiglou, Yuan Ge, Allen W Chan, Lidong Liu, Jie Lu, James G McLarnon, Yu Tian Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76860 (2013)
Neural stem cell (NSC) replacement therapy is considered a promising cell replacement therapy for various neurodegenerative diseases. However, the low rate of NSC survival and neurogenesis currently limits its clinical potential. Here, we examined if
Externí odkaz:
https://doaj.org/article/5df076a3486949e59135a5ebd52f3169
Autor:
Allen W. Chan, James D. Boyd, Jeffrey M. LeDue, Paul D. Metzak, Alexander McGirr, Timothy H. Murphy
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Medically unexplained symptoms in depression are common. These individual-specific complaints are often considered an ‘idiom of distress’, yet animal studies suggest that cortical sensory representations are flexible and influenced by spontaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf194fd136fea4c47bba1eac38dcd2b
http://europepmc.org/articles/PMC7026117
http://europepmc.org/articles/PMC7026117
Publikováno v:
The Journal of Neuroscience. 37:7513-7533
Connectivity mapping based on resting-state activity in mice has revealed functional motifs of correlated activity. However, the rules by which motifs organize into larger functional modules that lead to hemisphere wide spatial-temporal activity sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df541341253cb0e35d1b091fc7095dc
https://doi.org/10.1523/jneurosci.3560-16.2017
https://doi.org/10.1523/jneurosci.3560-16.2017
Publikováno v:
J Neurophysiol
During slow-wave sleep and anesthesia, mammalian cortex exhibits a synchronized state during which neurons shift from a largely nonfiring to a firing state, known as an Up-state transition. Up-state transitions may constitute the default activity pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea868fc0a1260e63a5a97362123937eb
https://pubmed.ncbi.nlm.nih.gov/31433725
https://pubmed.ncbi.nlm.nih.gov/31433725