Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Allen M Vong"'
Autor:
Priyadharshini eDevarajan, Bianca eBautista, Allen M Vong, Karl Kai McKinstry, Tara Marlene Strutt, Susan L Swain
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Influenza viral evolution presents a formidable challenge to vaccination due to the virus’ ability to rapidly mutate to evade immune responses. Live influenza infections generate large and diverse CD4 effector T cell responses that yield highly pro
Externí odkaz:
https://doaj.org/article/d44f19d5082545b8bbc4d1d9ba1089e3
Autor:
Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Noah J. Silverstein, Olivia Kugler-Umana, Bianca L. Bautista, Karen A. Kelly, Jeremy Luban, Susan L. Swain
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113429- (2023)
Externí odkaz:
https://doaj.org/article/370f4f484e794576b3fda940ba2c76b5
Autor:
Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Olivia Kugler-Umana, Bianca L. Bautista, Michael C. Jones, Karen A. Kelly, Jingya Xia, Susan L. Swain
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Influenza infection elicits strong, long-lived protective antibodies, but most current influenza vaccines give weaker, short-lived protection. We noted that live virus is still replicating, making antigen and causing inflammation at 7 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6efbd2657f17da35c340071eadb01eb2
https://doi.org/10.1073/pnas.2111064119
https://doi.org/10.1073/pnas.2111064119
Autor:
Priyadharshini, Devarajan, Allen M, Vong, Catherine H, Castonguay, Olivia, Kugler-Umana, Bianca L, Bautista, Michael C, Jones, Karen A, Kelly, Jingya, Xia, Susan L, Swain
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(8)
While influenza infection induces robust, long-lasting, antibody responses and protection, including the T follicular helper cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e0d7c17a85bdf2fea44d0c68de3ee2e
https://pubmed.ncbi.nlm.nih.gov/35177472
https://pubmed.ncbi.nlm.nih.gov/35177472
Autor:
Priyadharshini Devarajan, Yi Kuang, Wenliang Zhang, Allen M. Vong, Susan L. Swain, Jingya Xia, Vinayak Brahmakshatriya
Publikováno v:
The Journal of Immunology. 198:2819-2833
Naive CD4 T cell responses, especially their ability to help B cell responses, become compromised with aging. We find that using APC pretreated ex vivo with TLR agonists, polyinosinic-polycytidylic acid and CpG, to prime naive CD4 T cells in vivo, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f179e425c6ccfdd0356f7bff95d1c560
https://doi.org/10.4049/jimmunol.1601119
https://doi.org/10.4049/jimmunol.1601119
Autor:
Leslie J. Berg, Yi Kuang, Catherine H. Castonguay, Matthew D. Brauner, Ribhu Nayar, Priyadharshini Devarajan, Nikki B. Marshall, Allen M. Vong, Susan L. Swain, Stephen L. Nutt, Elizabeth Schutten
Publikováno v:
The Journal of Immunology. 198:1142-1155
CD4 T cells can differentiate into multiple effector subsets, including ThCTL that mediate MHC class II–restricted cytotoxicity. Although CD4 T cell–mediated cytotoxicity has been reported in multiple viral infections, their characteristics and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df18d5f78aed64a481b7883528585b1
https://doi.org/10.4049/jimmunol.1601297
https://doi.org/10.4049/jimmunol.1601297
Autor:
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Bianca L Bautista, Michael C Jones, Olivia Kugler-Umana, Susan L Swain
Publikováno v:
The Journal of Immunology. 206:103.11-103.11
Functionally specialized, tissue-restricted CD4 effector subsets such as T helper cytotoxic cells (ThCTL) in the infected tissue and T follicular helper cells (TFH) in secondary lymphoid organs develop after Th1 and other effectors. Following influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c83c4f2d74fbe4ec9122971896ceb2f
https://doi.org/10.4049/jimmunol.206.supp.103.11
https://doi.org/10.4049/jimmunol.206.supp.103.11
Autor:
Yi Kuang, Bianca Bautista, Michael C. Jones, Tara M. Strutt, Daniel Mott, Priyadharshini Devarajan, Susan L. Swain, Allen M. Vong, K. Kai McKinstry
Publikováno v:
The Journal of Immunology. 197:3936-3949
Although memory CD4 T cells are critical for effective immunity to pathogens, the mechanisms underlying their generation are still poorly defined. We find that following murine influenza infection, most effector CD4 T cells undergo apoptosis unless t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae075f96a385f7c321928da8a5ef1044
https://doi.org/10.4049/jimmunol.1600838
https://doi.org/10.4049/jimmunol.1600838
Autor:
Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Bianca L Bautista, Susan L Swain
Publikováno v:
The Journal of Immunology. 202:140.10-140.10
Key specialized tissue-restricted CD4 effector subsets such as T helper cytotoxic cells (ThCTL) in the infected tissue and T follicular helper cells (TFH) in secondary lymphoid organs arise after other CD4 effectors (Th1, Th17) peak. In an influenza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94123baf0901ff6d31f2b645d66745f9
https://doi.org/10.4049/jimmunol.202.supp.140.10
https://doi.org/10.4049/jimmunol.202.supp.140.10
Publikováno v:
Molecular Immunology. 52:9-18
Nonobese diabetic (NOD) mice develop spontaneous autoimmune Type 1 diabetes (T1D) that results from the destruction of insulin secreting β cells by diabetogenic T cells. The activation of autoreactive T cells occurs in the pancreatic lymph nodes (PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c67ddab93167e974608d10eaaf97a8
https://doi.org/10.1016/j.molimm.2012.04.004
https://doi.org/10.1016/j.molimm.2012.04.004