Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer

Autor: Esmeralda C. Marginean, Joanna Gotfrit, Horia Marginean, Daniel W. Yokom, Justin J. Bateman, Manijeh Daneshmand, Shelly Sud, Allen M. Gown, Derek Jonker, Timothy Asmis, Rachel A. Goodwin

Publikováno v: Translational Oncology, Vol 14, Iss 2, Pp 100996- (2021)

Background: Signal Transducer and Activator of Transcription-3 (STAT3) mediates cellular functions. We assessed the IHC expression of phosphorylated STAT3 (pSTAT3) in paired primary tumors and liver metastases in patients with advanced stage colorect

Externí odkaz: https://doaj.org/article/f0006ae798894edfa766a8a21f95b1c6

Commentary on Lehr, Hans-Anton, et al. (1997)

Autor: Allen M, Gown

Publikováno v: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::535309f12b6ad48ec6c5977a93cfe7bb
https://pubmed.ncbi.nlm.nih.gov/36546603

Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study

Autor: Balazs Acs, Samuel C.Y. Leung, Kelley M. Kidwell, Indu Arun, Renaldas Augulis, Sunil S. Badve, Yalai Bai, Anita L. Bane, John M.S. Bartlett, Jane Bayani, Gilbert Bigras, Annika Blank, Henk Buikema, Martin C. Chang, Robin L. Dietz, Andrew Dodson, Susan Fineberg, Cornelia M. Focke, Dongxia Gao, Allen M. Gown, Carolina Gutierrez, Johan Hartman, Zuzana Kos, Anne-Vibeke Lænkholm, Arvydas Laurinavicius, Richard M. Levenson, Rustin Mahboubi-Ardakani, Mauro G. Mastropasqua, Sharon Nofech-Mozes, C. Kent Osborne, Frédérique M. Penault-Llorca, Tammy Piper, Mary Anne Quintayo, Tilman T. Rau, Stefan Reinhard, Stephanie Robertson, Roberto Salgado, Tomoharu Sugie, Bert van der Vegt, Giuseppe Viale, Lila A. Zabaglo, Daniel F. Hayes, Mitch Dowsett, Torsten O. Nielsen, David L. Rimm, Lisa M. McShane, Torsten Nielsen, Samuel Leung, Signe Borgquist, Angela Chan, Carsten Denkert, Anna Ehinger, Matthew Ellis, Margaret Flowers, Chad Galderisi, Abhi Gholap, Douglas J. Hartman, Judith C. Hugh, Anagha Jadhav, Elizabeth N. Kornaga, Hans Kreipe, Richard Levenson, Mauro Mastropasqua, Takuya Moriya, Hongchao Pan, Liron Pantanowitz, Ernesta Paola Neri, Mei-Yin Polley, Jason Ruan, Takashi Sakatani, Lois Shepherd, Ian Smith, Joseph Sparano, Melanie Spears, Malini Srinivasan, Jane Starczynski, Austin Todd, Shakeel Virk, Yihong Wang, Hua Yang, Zhiwei Zhang, Inti Zlobec

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, vol 35, iss 10
Acs, Balazs; Leung, Samuel C Y; Kidwell, Kelley M; Arun, Indu; Augulis, Renaldas; Badve, Sunil S; Bai, Yalai; Bane, Anita L; Bartlett, John M S; Bayani, Jane; Bigras, Gilbert; Blank, Annika; Buikema, Henk; Chang, Martin C; Dietz, Robin L; Dodson, Andrew; Fineberg, Susan; Focke, Cornelia M; Gao, Dongxia; Gown, Allen M; ... (2022). Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study. Modern pathology, 35(10), pp. 1362-1369. Springer Nature 10.1038/s41379-022-01104-9
Modern Pathology
Modern Pathology, 2022, 35 (10), pp.1362-1369. ⟨10.1038/s41379-022-01104-9⟩
Acs, B & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2022, ' Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer : a multi-operator and multi-institutional study ', Modern Pathology, vol. 35, no. 10, pp. 1362-1369 . https://doi.org/10.1038/s41379-022-01104-9
Modern pathology, London : Springer Science and Business Media LLC, 2022, vol. 35, p. 1362-1369
on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2022, ' Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer : a multi-operator and multi-institutional study ', Modern Pathology, vol. 35, no. 10, pp. 1362-1369 . https://doi.org/10.1038/s41379-022-01104-9
Modern Pathology, Nature Publishing Group: Open Access Hybrid Model Option B, In press, ⟨10.1038/s41379-022-01104-9⟩
Modern Pathology. Nature Publishing Group

International audience; Abstract Ki67 has potential clinical importance in breast cancer but has yet to see broad acceptance due to inter-laboratory variability. Here we tested an open source and calibrated automated digital image analysis (DIA) plat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bf7cdeab8408b5113eef8d7ac1df1e
https://escholarship.org/uc/item/8h49n0kx

A Pilot Validation Study Comparing FIBI, a Slide-Free Imaging Method, with Standard FFPE H&E Tissue Section Histology for Primary Surgical Pathology Diagnosis

Autor: Alexander D. Borowsky, Richard M. Levenson, Allen M. Gown, Taryn Morningstar, Thomas A. Fleury, Gregory Henderson, Kurt Schaberg, Amelia B. Sybenga, Eric. F. Glassy, Sandra L. Taylor, Farzad Fereidouni

IntroductionDigital pathology whole slide images (WSI) have been recently approved by the FDA for primary diagnosis in clinical surgical pathology practices. These WSI are generated by digitally scanning standard formalin-fixed and paraffin-embedded

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a753c819a67bab6ee41cc105ce24bbea
https://doi.org/10.1101/2022.03.10.22272226

Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections

Autor: Giuseppe Viale, Zuzana Kos, Allen M Gown, John M. S. Bartlett, Samuel C Y Leung, Andrew Dodson, Dongxia Gao, Frédérique Penault-Llorca, Jane Starczynski, Roberto Salgado, Mauro G. Mastropasqua, Sharon Nofech-Mozes, C. Kent Osborne, Signe Borgquist, Mitch Dowsett, Bert van der Vegt, Torsten O. Nielsen, Takuya Moriya, Takashi Sakatani, Tammy Piper, Carolina Gutierrez, Tomoharu Sugie, Anita Bane, Martin C. Chang, Susan Fineberg, Cornelia M Focke, Lila Zabaglo, Anna Ehinger, Lisa M. McShane, Sunil Badve, Daniel F. Hayes, Judith Hugh, Anne-Vibeke Lænkholm, Indu Arun

Publikováno v: Histopathology, 75(2), 225-235. Wiley
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A, Mastropasqua, M G, Moriya, T, Nofech-mozes, S, Osborne, C K, Penault-llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, Vegt, B, Viale, G, Hayes, D F, Mcshane, L M & Dowsett, M 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration ', Histopathology . https://doi.org/10.1111/his.13880
Leung, S C Y, Nielsen, T O, Zabaglo, L A, Arun, I, Badve, S S, Bane, A L, Bartlett, J M S, Borgquist, S, Chang, M C, Dodson, A, Ehinger, A, Fineberg, S, Focke, C M, Gao, D, Gown, A M, Gutierrez, C, Hugh, J C, Kos, Z, Lænkholm, A V, Mastropasqua, M G, Moriya, T, Nofech-Mozes, S, Osborne, C K, Penault-Llorca, F M, Piper, T, Sakatani, T, Salgado, R, Starczynski, J, Sugie, T, van der Vegt, B, Viale, G, Hayes, D F, McShane, L M, Dowsett, M & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG) 2019, ' Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections : an international multicentre collaboration ', Histopathology, vol. 75, no. 2, pp. 225-235 . https://doi.org/10.1111/his.13880

Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b17a84211148464ea55a0e4b7f71b32
https://research.rug.nl/en/publications/6062a661-6dbf-465f-a0f6-083331084619