Comprehensive molecular and morphological resolution of blubber stratification in a deep-diving, fasting-adapted seal

Autor: Khudyakov, JI, Allen, KN, Crocker, DE, Trost, NS, Roberts, AH, Pirard, L, Debier, C, Piotrowski, ER, Vázquez-Medina, JP

Publikováno v: Frontiers in Physiology, Vol. 13, no.1, p. 1 (2022)

Blubber is a modified subcutaneous adipose tissue in marine mammals that provides energy storage, thermoregulation, hydrodynamic locomotion, and buoyancy. Blubber displays vertical stratification by lipid content, fatty acid composition, and vascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dff62057088be903a9208c88fc04af
https://hdl.handle.net/2078.1/272428

Evaluating atezolizumab in patients with urinary tract squamous cell carcinoma (AURORA): study protocol for a single arm, open-label, multicentre, phase II clinical trial

Autor: Simon Crabb, Robin Wickens, Sarah Jane-Bibby, Denise Dunkley, Megan Lawrence, Allen Knight, Robert Jones, Alison Birtle, Robert Huddart, Mark Linch, Jonathan Martin, Adam Coleman, Konstantinos Boukas, Hannah Markham, Gareth Griffiths

Publikováno v: BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Background Bladder and urinary tract cancers account for approximately 21,000 new diagnoses and 5,000 deaths annually in the UK. Approximately 90% are transitional cell carcinomas where advanced disease is treated with platinum based chemoth

Externí odkaz: https://doaj.org/article/883dd092ab0e4728b9ca62b8a51e9be0

Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases

Autor: Shoichet, Brian, Babbitt, Patricia, London, N, Farelli, JD, Brown, SD, Liu, C, Huang, H, Korczynska, M, Al-Obaidi, NF, Babbitt, PC, Almo, SC, Allen, KN

Publikováno v: Shoichet, Brian; Babbitt, Patricia; London, N; Farelli, JD; Brown, SD; Liu, C; et al.(2015). Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/06x13945

© 2014 American Chemical Society.Enzyme function prediction remains an important open problem. Though structure-based modeling, such as metabolite docking, can identify substrates of some enzymes, it is ill-suited to reactions that progress through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4dcd99b491d85352d1b4df77517b50d1
http://www.escholarship.org/uc/item/06x13945

The associations between diet and physical activity with body composition and walking a timed distance in adults with Prader–Willi syndrome

Autor: Susan G. Woods, Allen Knehans, Sandra Arnold, Carol Dionne, Leah Hoffman, Peggy Turner, Jonathan Baldwin

Publikováno v: Food & Nutrition Research, Vol 62, Iss 0, Pp 1-11 (2018)

Background: Research on aging in Prader–Willi syndrome (PWS) is limited, although people with PWS are living longer. Individuals with PWS present with high fat mass, low lean mass, and low levels of physical activity (PA). Previous reports in child

Externí odkaz: https://doaj.org/article/525b4bb3d87f44e995fe835235e6df53

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