Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Allen Jankeel"'
Autor:
Suhas Sureshchandra, Michael Z. Zulu, Brianna M. Doratt, Allen Jankeel, Delia Tifrea, Robert Edwards, Monica Rincon, Nicole E. Marshall, Ilhem Messaoudi
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110938- (2022)
Summary: While severe coronavirus 2019 (COVID-19) is associated with immune activation at the maternal-fetal interface, responses to asymptomatic/mild severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy remain unkn
Externí odkaz:
https://doaj.org/article/d5555b8dc8e64730963623c27f78b051
Autor:
Wakako Furuyama, Kyle Shifflett, Amanda N. Pinski, Amanda J. Griffin, Friederike Feldmann, Atsushi Okumura, Tylisha Gourdine, Allen Jankeel, Jamie Lovaglio, Patrick W. Hanley, Tina Thomas, Chad S. Clancy, Ilhem Messaoudi, Kyle L. O’Donnell, Andrea Marzi
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The ongoing pandemic of coronavirus (CoV) disease 2019 (COVID-19) continues to exert a significant burden on health care systems worldwide. With limited treatments available, vaccination remains an effective strategy to counter transmission
Externí odkaz:
https://doaj.org/article/b1453d6466b74f36931bb1ccc3680e0a
Autor:
Suhas Sureshchandra, Sloan A. Lewis, Brianna M. Doratt, Allen Jankeel, Izabela Coimbra Ibraim, Ilhem Messaoudi
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
mRNA vaccines for SARS-CoV-2 have shown exceptional clinical efficacy, providing robust protection against severe disease. However, our understanding of transcriptional and repertoire changes following full vaccination remains incomplete. We used scR
Externí odkaz:
https://doaj.org/article/d65adc9e7479436aa36a09740234a63a
Autor:
Andrea Marzi, Allen Jankeel, Andrea R. Menicucci, Julie Callison, Kyle L. O’Donnell, Friederike Feldmann, Amanda N. Pinski, Patrick W. Hanley, Ilhem Messaoudi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Marburg virus (MARV) is a member of the filovirus family that causes hemorrhagic disease with high case fatality rates. MARV is on the priority list of the World Health Organization for countermeasure development highlighting its potential impact on
Externí odkaz:
https://doaj.org/article/517ce9348a0142e6a98fc9c7faa08a84
Autor:
Suhas Sureshchandra, Nicole E. Marshall, Norma Mendoza, Allen Jankeel, Michael Z. Zulu, Ilhem Messaoudi
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102690- (2021)
Summary: Pregravid obesity is associated with several adverse maternal health outcomes, such as increased risk of infection, suggesting an altered immunological state. However, the mechanisms by which obesity disrupts the pregnancy “immune clock”
Externí odkaz:
https://doaj.org/article/36ca42399393439dba2e6567b132c151
Autor:
Suhas Sureshchandra, Norma Mendoza, Allen Jankeel, Randall M. Wilson, Nicole E. Marshall, Ilhem Messaoudi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pregravid obesity has been shown to disrupt the development of the offspring’s immune system and increase susceptibility to infection. While the mechanisms underlying the impact of maternal obesity on fetal myeloid cells are emerging, the consequen
Externí odkaz:
https://doaj.org/article/89fbc98be8f14a88ba2306d2493fb142
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Toxoplasma gondiiT. gondii
Externí odkaz:
https://doaj.org/article/5398c25f47e342859a96eef453f3646b
Autor:
Armond L. Franklin-Murray, Sharmila Mallya, Allen Jankeel, Suhas Sureshchandra, Ilhem Messaoudi, Melissa B. Lodoen
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Toxoplasma gondii can infect and replicate in vascular endothelial cells prior to entering host tissues. However, little is known about the molecular interactions at the parasite-endothelial cell interface. We demonstrate that T. gondii infe
Externí odkaz:
https://doaj.org/article/0f8bc6049ce545a388eee34906463a26
Autor:
Courtney Woolsey, Andrea R. Menicucci, Robert W. Cross, Priya Luthra, Krystle N. Agans, Viktoriya Borisevich, Joan B. Geisbert, Chad E. Mire, Karla A. Fenton, Allen Jankeel, Sneha Anand, Hideki Ebihara, Thomas W. Geisbert, Ilhem Messaoudi, Christopher F. Basler
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3032-3046.e6 (2019)
Summary: Zaire ebolavirus (EBOV) VP35 protein is a suppressor of type I interferon (IFN) production, an inhibitor of dendritic cell maturation, and a putative virulence determinant. Here, a recombinant EBOV encoding a mutant VP35 virus (VP35m) is dem
Externí odkaz:
https://doaj.org/article/fe494133553a485dafbc2ad2bd373312
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Ebola virus (EBOV) is a single-stranded RNA virus that causes Ebola virus disease (EVD), characterized by excessive inflammation, lymphocyte apoptosis, hemorrhage, and coagulation defects leading to multiorgan failure and shock. Recombinant
Externí odkaz:
https://doaj.org/article/22b8b5e8b08d41a8839aae168a0e384a