Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Allen J. Gies"'
Autor:
Valentina K. Todorova, Stephanie D. Byrum, Allen J. Gies, Cade Haynie, Hunter Smith, Nathan S. Reyna, Issam Makhoul
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 613-630 (2022)
Background: Neoadjuvant chemotherapy (NACT) is an increasingly used approach for treatment of breast cancer. The pathological complete response (pCR) is considered a good predictor of disease-specific survival. This study investigated whether circula
Externí odkaz:
https://doaj.org/article/a9de7a58d45b4367965c9fe7e29d3893
Autor:
Valentina K. Todorova, Stephanie D. Byrum, Samuel G. Mackintosh, Azemat Jamshidi-Parsian, Allen J. Gies, Charity L. Washam, Samir V. Jenkins, Timothy Spiva, Emily Bowman, Nathan S. Reyna, Robert J. Griffin, Issam Makhoul
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13098 (2023)
Infection with hepatitis B virus (HBV) is a main risk factor for hepatocellular carcinoma (HCC). Extracellular vesicles, such as exosomes, play an important role in tumor development and metastasis, including regulation of HBV-related HCC. In this st
Externí odkaz:
https://doaj.org/article/3b02270626c0415bbc26294adef43c6e
Autor:
Ishan Barman, Narasimhan Rajaram, Alan J. Tackett, Stephanie D. Byrum, Charles M. Quick, Allen J. Gies, Nathan L. Avaritt, David E. Lee, Jesse D. Ivers, Paola Monterroso Diaz, Piyush Raj, Joel Rodriguez Troncoso, Santosh Kumar Paidi
Cancer immunotherapy provides durable clinical benefit in only a small fraction of patients, and identifying these patients is difficult due to a lack of reliable biomarkers for prediction and evaluation of treatment response. Here, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624098e667551aa0c755db084de732d1
https://doi.org/10.1158/0008-5472.c.6513670
https://doi.org/10.1158/0008-5472.c.6513670
Autor:
Alan J. Tackett, Gang Greg Wang, Thomas F. Gajewski, Nukhet Aykin-Burns, Rick D. Edmondson, Samuel G. Mackintosh, Tung-Chin Chiang, Kimberly J. Krager, Jason B. Williams, Hidetaka Uryu, Jeong Hyun Ahn, Samrat Roy Choudhury, Charity L. Washam, Allen J. Gies, Stephanie D. Byrum, Aaron J. Storey, Erin M. Taylor, Bradley D. Shields, Brian Koss
T-cell exhaustion in cancer is linked to poor clinical outcomes, where evidence suggests T-cell metabolic changes precede functional exhaustion. Direct competition between tumor-infiltrating lymphocytes (TIL) and cancer cells for metabolic resources
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2aed658cb8479aa41c12a11abbf7a0
https://doi.org/10.1158/0008-5472.c.6512143.v1
https://doi.org/10.1158/0008-5472.c.6512143.v1
Autor:
Ishan Barman, Narasimhan Rajaram, Alan J. Tackett, Stephanie D. Byrum, Charles M. Quick, Allen J. Gies, Nathan L. Avaritt, David E. Lee, Jesse D. Ivers, Paola Monterroso Diaz, Piyush Raj, Joel Rodriguez Troncoso, Santosh Kumar Paidi
Supplementary figures S1 and S2 and supplementary tables ST1 and ST2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6ded52a84d28c4bcdcc53106ee3456
https://doi.org/10.1158/0008-5472.22430638
https://doi.org/10.1158/0008-5472.22430638
Autor:
Alan J. Tackett, Gang Greg Wang, Thomas F. Gajewski, Nukhet Aykin-Burns, Rick D. Edmondson, Samuel G. Mackintosh, Tung-Chin Chiang, Kimberly J. Krager, Jason B. Williams, Hidetaka Uryu, Jeong Hyun Ahn, Samrat Roy Choudhury, Charity L. Washam, Allen J. Gies, Stephanie D. Byrum, Aaron J. Storey, Erin M. Taylor, Bradley D. Shields, Brian Koss
Figure S1-7. Figure S1: Assessing the effect of EZH2i on in vitro T cell cytotoxic function. Figure S2: Systems approach uncovers drivers of T cell exhaustion resulting from EZH2-inhibtion. Figure S3: Loss of EZH2 function leads to metabolic exhausti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7199995713bf285261746195a1b94520
https://doi.org/10.1158/0008-5472.22425820
https://doi.org/10.1158/0008-5472.22425820
Autor:
Narasimhan Rajaram, Piyush Raj, Charles M. Quick, Jesse D. Ivers, Nathan L. Avaritt, Ishan Barman, Alan J. Tackett, David E. Lee, Paola Monterroso Diaz, Allen J. Gies, Santosh Kumar Paidi, Joel Rodriguez Troncoso, Stephanie D. Byrum
Publikováno v:
Cancer Res
Cancer immunotherapy provides durable clinical benefit in only a small fraction of patients, and identifying these patients is difficult due to a lack of reliable biomarkers for prediction and evaluation of treatment response. Here, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fe0b77404f9c0e8c484337a02c972c
https://europepmc.org/articles/PMC8841097/
https://europepmc.org/articles/PMC8841097/
Autor:
Brian, Koss, Bradley D, Shields, Erin M, Taylor, Aaron J, Storey, Stephanie D, Byrum, Allen J, Gies, Charity L, Washam, Samrat Roy, Choudhury, Jeong, Hyun Ahn, Hidetaka, Uryu, Jason B, Williams, Kimberly J, Krager, Tung-Chin, Chiang, Samuel G, Mackintosh, Rick D, Edmondson, Nukhet, Aykin-Burns, Thomas F, Gajewski, Gang Greg, Wang, Alan J, Tackett
Publikováno v:
Cancer Res
T cell exhaustion in cancer is linked to poor clinical outcomes, where evidence suggests T cell metabolic changes precede functional exhaustion. Direct competition between tumor-infiltrating lymphocytes (TIL) and cancer cells for metabolic resources
Publikováno v:
Applied and Environmental Microbiology. 63:4185-4190
The bacteriocin BacR1 was purified from culture supernatant of Staphylococcus aureus UT0007 by sequential ammonium sulfate precipitation, cation-exchange chromatography, and C4 reverse-phase chromatography steps. Mass spectrographic analysis indicate