Oxidative Stress in the Pathogenesis of Ovarian Cancer

Autor: S. Winkins Santosh, Allen J. Freddy, Daphne Winkins

Publikováno v: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811654213
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea713ab7cec8097d1a2d4d4739660cb
https://doi.org/10.1007/978-981-16-5422-0_226

SARS-CoV-2/human interactome reveals ACE2 locus crosstalk with the immune regulatory network in the host

Autor: Christy Lite, Melita Juliet, Allen J. Freddy, Shiek S. S. J. Ahmed

Publikováno v: Pathogens and Disease

Severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2), remains to be a threat across the globe. SARS-CoV-2 entry into the host is mediated by binding of viral spike protein to the Human angiotensin-converting enzyme 2 (ACE2) receptor. ACE2 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c338dd958cfcf22af63a46310654e41
https://doi.org/10.1093/femspd/ftab005

Chronic intake of 4-Methylimidazole induces Hyperinsulinemia and Hypoglycaemia via Pancreatic Beta Cell Hyperplasia and Glucose Dyshomeostasis

Autor: Tharmarajan Ramprasath, Prerna Kulshrestha, Allen J. Freddy, Shanmugarajan Suresh, Ganesan Velmurugan, Subbiah Ramasamy, Govindan Sadasivam Selvam, Karuppusamy V. Karthik, Gilles Mithieux, Alexander R. Lyon, Balakrishnan Rekha, Sivakumar Anusha

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.17037. ⟨10.1038/s41598-018-35071-6⟩

Caramel colours are the preferential food colouring agent globally, reaches wide age groups through eatables. Colas, a sweetened carbonated drink are most common caramel coloured beverage and its consumption is linked with diabetes, obesity, pancreat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61a37f5880fa822a68f31c5382f7e76
http://europepmc.org/articles/PMC6242838

Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis

Autor: Yacob Jenifer Christy, Leishman John Thumburaj, Ayothi Parthasarathy, Jeyaprakash Rajendhran, Albert Abhishek, Boominathan Meganathan, Varadaraj Vasudevan, Shanavas Syed Mohamed Puhari, D.D. Venkatesh Babu, Muthuirulan Pushpanathan, Gilles Mithieux, Allen J. Freddy, Kannan Suganya, Tharmarajan Ramprasath, Rajamani Koushick Rajmohan, Sivakumar Anusha, Vasudevan Dinakaran, Kumaravel Velayutham, Ganesan Divya, Eldho Paul, Alexander R. Lyon, Kamaraj Raju, Ganesan Velmurugan, Subbiah Ramasamy, Krishnan Swaminathan, Balakrishnan Rekha, Maruthan Karthik, Narayanan Kalyanaraman, Mani Dhivakar, Balakrishnan Jeyakumar

Publikováno v: Genome Biology
Genome Biology, BioMed Central, 2017, 18 (1), ⟨10.1186/s13059-016-1134-6⟩

Background Organophosphates are the most frequently and largely applied insecticide in the world due to their biodegradable nature. Gut microbes were shown to degrade organophosphates and cause intestinal dysfunction. The diabetogenic nature of organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa8875659c0a6c86da44b93e21169a4
https://pubmed.ncbi.nlm.nih.gov/28115022

PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

Autor: Gopeshwar, Narayan, Dongxu, Xie, Allen J, Freddy, Ganchimeg, Ishdorj, Catherine, Do, Prakash, Satwani, Hema, Liyanage, Lorraine, Clark, Sergey, Kisselev, Subhadra V, Nandula, Luigi, Scotto, Bachir, Alobeid, David, Savage, Benjamin, Tycko, Owen A, O'Connor, Govind, Bhagat, Vundavalli V, Murty

Publikováno v: Genes, chromosomescancer. 52(11)

PCDH10 is epigenetically inactivated in multiple tumor types; however, studies in mature lymphoid malignancies are limited. Here, we have investigated the presence of promoter hypermethylation of the PCDH10 gene in a large cohort of well-characterize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::388ab39f2a593522faa477c933eecc01
https://pubmed.ncbi.nlm.nih.gov/23929756