Výsledky vyhledávání - "Allen J. Freddy"

Oxidative Stress in the Pathogenesis of Ovarian Cancer

Autor: S. Winkins Santosh, Allen J. Freddy, Daphne Winkins

Publikováno v: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811654213
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea713ab7cec8097d1a2d4d4739660cb
https://doi.org/10.1007/978-981-16-5422-0_226

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SARS-CoV-2/human interactome reveals ACE2 locus crosstalk with the immune regulatory network in the host

Autor: Christy Lite, Melita Juliet, Allen J. Freddy, Shiek S. S. J. Ahmed

Publikováno v: Pathogens and Disease

Severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2), remains to be a threat across the globe. SARS-CoV-2 entry into the host is mediated by binding of viral spike protein to the Human angiotensin-converting enzyme 2 (ACE2) receptor. ACE2 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c338dd958cfcf22af63a46310654e41
https://doi.org/10.1093/femspd/ftab005

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Intracellular ROS scavenging and antioxidant regulation of WL15 from cysteine and glycine-rich protein 2 demonstrated in zebrafish in vivo model

Autor: Allen J. Freddy, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu, Jesu Arockiaraj, Ajay Guru, N.T. Saraswathi, Praveen Kumar Issac, Christy Lite, Aziz Arshad, Mukesh Pasupuleti

Publikováno v: Developmental & Comparative Immunology. 114:103863

Antioxidant peptides are naturally present in food, especially in fishes, and are considered to contain rich source of various bioactive compounds that are structurally heterogeneous. This study aims to identify and characterize the antioxidant prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a213358f611805ddaade0120278ccc4a
https://doi.org/10.1016/j.dci.2020.103863

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Chronic intake of 4-Methylimidazole induces Hyperinsulinemia and Hypoglycaemia via Pancreatic Beta Cell Hyperplasia and Glucose Dyshomeostasis

Autor: Tharmarajan Ramprasath, Prerna Kulshrestha, Allen J. Freddy, Shanmugarajan Suresh, Ganesan Velmurugan, Subbiah Ramasamy, Govindan Sadasivam Selvam, Karuppusamy V. Karthik, Gilles Mithieux, Alexander R. Lyon, Balakrishnan Rekha, Sivakumar Anusha

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.17037. ⟨10.1038/s41598-018-35071-6⟩

Caramel colours are the preferential food colouring agent globally, reaches wide age groups through eatables. Colas, a sweetened carbonated drink are most common caramel coloured beverage and its consumption is linked with diabetes, obesity, pancreat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61a37f5880fa822a68f31c5382f7e76
http://europepmc.org/articles/PMC6242838

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PCDH10promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

Autor: Hema Liyanage, Luigi Scotto, Catherine Do, Benjamin Tycko, Owen A. O'Connor, Vundavalli V. Murty, Gopeshwar Narayan, Sergey Kisselev, Lorraine N. Clark, Allen J. Freddy, Govind Bhagat, Bachir Alobeid, Ganchimeg Ishdorj, Subhadra V. Nandula, Prakash Satwani, Dongxu Xie, David G. Savage

Publikováno v: Genes, Chromosomes and Cancer. 52:1030-1041

PCDH10 is epigenetically inactivated in multiple tumor types; however, studies in mature lymphoid malignancies are limited. Here, we have investigated the presence of promoter hypermethylation of the PCDH10 gene in a large cohort of well-characterize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b7edf2da3b5cf90f287a4856ceeff7a
https://doi.org/10.1002/gcc.22098

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Abundant and Altered Expression of PIWI-Interacting RNAs during Cardiac Hypertrophy

Autor: Pandi Gopal, Y. Christy Jenifer, Allen J. Freddy, Ganesan Velmurugan, Subbiah Ramasamy, K. Shanmugha Rajan, K. Kalpana, D.D. Venkatesh Babu, S. Krithika, Tharmarajan Ramprasath, George William Jn

Publikováno v: Heart, lungcirculation. 25(10)

Background The discovery of PIWI-interacting RNAs (piRNAs) has fundamentally changed our understanding of post transcriptional regulation of transposons and other genes. Unlike miRNA and siRNA, the piRNAs are the most abundant but least studied RNA s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f69e1971f8a6bcc3c6fe3bbd26df88
https://pubmed.ncbi.nlm.nih.gov/27067666

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PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

Autor: Gopeshwar, Narayan, Dongxu, Xie, Allen J, Freddy, Ganchimeg, Ishdorj, Catherine, Do, Prakash, Satwani, Hema, Liyanage, Lorraine, Clark, Sergey, Kisselev, Subhadra V, Nandula, Luigi, Scotto, Bachir, Alobeid, David, Savage, Benjamin, Tycko, Owen A, O'Connor, Govind, Bhagat, Vundavalli V, Murty

Publikováno v: Genes, chromosomescancer. 52(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::388ab39f2a593522faa477c933eecc01
https://pubmed.ncbi.nlm.nih.gov/23929756

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Distinct involvement of 9p21-24 and 13q14.1-14.3 chromosomal regions in raw betel-nut induced esophageal cancers in the state of Meghalaya, India

Autor: Henry B. Nongrum, Atanu Banerjee, Avdhesh Kumar Rai, Mohammad Safiqul Islam, Allen J. Freddy, Anupam Chatterjee, Sillarine Kurkalang, Hughbert Dkhar, Gordon M. Rangad

Publikováno v: Asian Pacific journal of cancer prevention : APJCP. 13(6)

BACKGROUND Raw betel nut (RBN) chewing is an important contributing factor for esophageal squamous cell carcinoma (ESCC), although associated genomic changes remain unclear. One difficulty in assessing the effects of exclusively RBN induced genetic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020485dd9893c1a96609a47419622ffa
https://pubmed.ncbi.nlm.nih.gov/22938432

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Effect of coordinated ligands on antiproliferative activity and DNA cleavage property of three mononuclear Cu(II)-terpyridine complexes

Autor: Thomas Weyhermüller, V. M. Manikandamathavan, Allen J. Freddy, Balachandran Unni Nair, Venkatesan Subramanian, V. Rajapandian

Publikováno v: European journal of medicinal chemistry. 57

Three mononuclear copper(II) complexes, [Cu(tpy)Cl(2)] 1, [Cu(tpy)(NO(3))(2)(H(2)O)] 2 and [Cu(Ptpy)Cl(2)]·H(2)O·HCl 3 have been synthesised and characterized by various spectroscopic techniques and single crystal X-ray diffraction. Complexes 1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f79f65148319b21a4dae170964f9f17
https://pubmed.ncbi.nlm.nih.gov/22846797

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Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance

Autor: Gopeshwar Narayan, David G. Savage, Catherine E. McGuinn, Allen J. Freddy, Subhadra V. Nandula, Vundavalli V. Murty, Bachir Alobeid, Dongxu Xie, Hema Liyanage, Prakash Satwani, Govind Bhagat, Sergey Kisselev, Lorraine N. Clark, Shivakumar Subramaniyam, Ji Un Kang

Publikováno v: Genes, chromosomescancer. 50(12)

PCDH10has been implicated as a tumor suppressor, since epigenetic alterations of this gene have been noted in multiple tumor types. However, to date, studies regarding its role in acute and chronic leukemias are lacking. Here, we have investigated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14c0fac35c20824c4d1349e659153e7
https://pubmed.ncbi.nlm.nih.gov/21960365

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