Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Allen H. Heller"'
Publikováno v:
Epilepsia
Objective Diazepam buccal film (DBF) is in development for treatment of patients experiencing bouts of increased seizure activity. We assessed safety, tolerability, and usability of self‐ or caregiver‐administered DBF in the outpatient setting. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413e6c48b4d9e8b24c2b3465884c7b1d
https://pubmed.ncbi.nlm.nih.gov/32944970
https://pubmed.ncbi.nlm.nih.gov/32944970
Autor:
Stephen Paul Wargacki, David J. Wyatt, A. Mark Schobel, Allen H. Heller, Buan Carla Valenti, Cassie Jung
Publikováno v:
Epilepsia. 59:2153-2161
Objective Clobazam oral soluble film (COSF) is a novel dosage form under development for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome. The present study was undertaken to assess the pharmacokinetics of clobazam adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64eb05a9c5607ca0b41c04d494f68d18
https://doi.org/10.1111/epi.14581
https://doi.org/10.1111/epi.14581
Autor:
Michael A. Rogawski, Allen H. Heller
Publikováno v:
Epilepsybehavior : EB. 101
Benzodiazepines, including diazepam and midazolam, are the mainstay of treatment for seizure emergencies, including acute repetitive seizures. Nonparenteral dosage forms are used when parenteral (intravenous or intramuscular) dosing is not feasible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2da3813c88a1bb7d20860b0c5a1c05
https://pubmed.ncbi.nlm.nih.gov/31699662
https://pubmed.ncbi.nlm.nih.gov/31699662
Publikováno v:
Clinical Pharmacokinetics. 40:11-18
Moxifloxacin is a new 8-methoxyfluoroquinolone with a broad antibacterial spectrum. The purpose of the present study was to determine the effects of age and gender on pharmacokinetics, surrogate pharmacodynamics, safety and tolerability of a single d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c170a91edf764df12294ba0bfe12849e
https://doi.org/10.2165/00003088-200140001-00002
https://doi.org/10.2165/00003088-200140001-00002
Autor:
Debra S. Israel, William Rock, John T. Lettieri, Charles D. Sintek, John P. Toscano, Catherine Klein, Jennifer L. Stotka, Allen H. Heller, William R. Swaim, Ron E. Polk, Alan K. Kamada, Robert E. Pluhar
Publikováno v:
Clinical Infectious Diseases. 22:251-256
To determine if ciprofloxacin therapy alters the response to warfarin treatment, 36 adult patients attending three university-affiliated outpatient anticoagulation clinics randomly received a 12-day course of ciprofloxacin (750 mg twice daily) and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7793cc31b7ea921e0092f5a4779fae4
https://doi.org/10.1093/clinids/22.2.251
https://doi.org/10.1093/clinids/22.2.251
Autor:
Pavur Sundaresan, John Lettieri, Allen H. Heller, John J. Sramek, Neal R. Cutler, Suzanne Sawin
Publikováno v:
Annals of Pharmacotherapy. 28:1143-1148
OBJECTIVE: To evaluate the safety and tolerance of intravenous nimodipine administered via a peripheral vein in healthy male volunteers. DESIGN: Double-blind, placebo- and vehicle-controlled trial with three fixed-dose panels. SETTING: Inpatient infu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd669fa00b35f0bf4dbb1d23f3bc6eb
https://doi.org/10.1177/106002809402801001
https://doi.org/10.1177/106002809402801001
Publikováno v:
European journal of clinical pharmacology. 56(12)
The pharmacokinetics, safety, and tolerability of cerivastatin, a synthetic HMG-CoA reductase inhibitor were studied in 49 healthy volunteers. In this double-blind, parallel group, multiple-dose study, volunteers were randomized as age-matched, male-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c689d3f89ad43fd365f10f6022b2f8d
https://pubmed.ncbi.nlm.nih.gov/11317478
https://pubmed.ncbi.nlm.nih.gov/11317478
Autor:
Glenn Sipes, Harry Olson, Gerald Kolaja, Bruce Berger, Allen H. Heller, A.M. Monro, Patrick D. Lilly, Graham Betton, Peter Smith, Denise Robinson, Koen Van Deun, Karluss Thomas, Michael A. Dorato, James E. Sanders, William Bracken
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 32(1)
This report summarizes the results of a multinational pharmaceutical company survey and the outcome of an International Life Sciences Institute (ILSI) Workshop (April 1999), which served to better understand concordance of the toxicity of pharmaceuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b7955e2dfd3e43e69348210fe33dc2
https://pubmed.ncbi.nlm.nih.gov/11029269
https://pubmed.ncbi.nlm.nih.gov/11029269
Autor:
Jeffrey A. Stritar, José M. Vega, Jack A. Cook, Man-Wai Lo, Allen H. Heller, Andrew T. Chow, Brian P. Smith, Jeffrey S. Barrett, Scott D. Patterson, A. Lawrence Gould, Névine Zariffa, Vijay Batra
Publikováno v:
Journal of clinical pharmacology. 40(6)
The Food and Drug Administration (FDA) issued a second-draft guidance in August 1999 on the subject of in vivo bioequivalence, which is based on the concepts of individual and population bioequivalence (IBE and PBE, respectively). The intention of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d77972de7bd50d31e0a6a04626fab39
https://pubmed.ncbi.nlm.nih.gov/10868305
https://pubmed.ncbi.nlm.nih.gov/10868305
Autor:
Jeffrey A. Stritar, A. Lawrence Gould, Jack A. Cook, Jeffrey S. Barrett, José M. Vega, Man-Wai Lo, Scott D. Patterson, Névine Zariffa, Allen H. Heller, Vijay Batra, Andrew T. Chow, Brian P. Smith
Publikováno v:
Journal of clinical pharmacology. 40(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5d752d09118e95edf7f40d582b566
https://pubmed.ncbi.nlm.nih.gov/10868306
https://pubmed.ncbi.nlm.nih.gov/10868306